Novel NF-κB inhibitor and lipopolysaccharide (LPS)-induced nitric oxide production inhibitor

Self-assembling peptide, forming a hydrogel matrix to support growth of cells in the presence of an ionic solution, enhancing chondrogenic differentiation of bone marrow stromal cells (BMSCs)

Novel inhibitor of 70S ribosome by obstructing the peptide exit tunnel

First-in-class inhibitor of Kallikrein-related peptidase 6 (KLK6), promoting the differentiation of OPCs into mature oligodendrocytes in vitro

First-in-class inhibitor of Kallikrein-related peptidase 6 (KLK6), promoting the differentiation of OPCs into mature oligodendrocytes in vitro

Novel antibiotic sensitizer, promoting the rearrangement of the bacterial membrane that enables hydrophobic antibiotics to permeate, strongly sensitizing Gram-negative bacteria to linezolid (Lzd), rifampicin (Rif), or clarithromycin (Clr)

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CDK9 inhibitor, inhibiting transcription of GAPDH

Selective S1P3 agonist

Novel inhibitor of the BfrB-Bfd complex, binding BfrB in the P. aeruginosa cytosol, blocking the BfrB-Bfd interaction and inhibiting iron mobilization from BfrB, resulting in cytosolic iron limitation that is manifested in a pyoverdine hyperproduction phe

Novel inhibitor of the BfrB-Bfd complex, binding BfrB in the P. aeruginosa cytosol, blocking the BfrB-Bfd interaction and inhibiting iron mobilization from BfrB, resulting in cytosolic iron limitation that is manifested in a pyoverdine hyperproduction phe

Novel BACE1 inhibitor with a non-acidic heterocycle at the P1' position

Novel Potent Hematopoietic Prostaglandin D2 Synthase (H-PGDS) Inhibitor

Novel Potent and Selective EP4 Agonist

Novel inhibitor of amyloid-

Novel inhibitor of amyloid-β aggregation, ameliorating the neurodegenerative disorder

Novel enhancer of cGMP activity; Aortic smooth muscle relaxant

Novel enhancer of cGMP activity; Aortic smooth muscle relaxant

Natural anti-TNBC agent, significantly suppressing the triple-negative breast cancer (TNBC) tumor growth without causing side effects

Novel non-chain terminating nucleoside analog anti-HIV inhibitor

Novel selective, orally bioavailable, PAK4 allosteric modulator against triple negative breast cancer

Novel potent antimicrotubule agent, exhibiting potent cytotoxicity against HT-29 cells by strongly binding to tubulin and inducing microtubule depolymn.