Potent and selective inhibitor of ABHD6

TXA2/prostaglandin endoperoxide receptor antagonist

Thyroid hormone receptor β (TRβ) selective agonist

Hypoxic cell radiosensitizer

Novel selective DYRK1A inhibitor

Novel potent and selective inhibitor of Hsp90β

Novel protein farnesyltransferase inhibitor

Potent Kv1.5 inhibitor

Novel neuroprotectant, inhibiting Kv2.1-syntaxin molecular interaction

Novel Preferable Phosphodiesterase 4B (PDE4B) Inhibitor, Decreasing Cocaine-Mediated Reward Properties in Vivo

Ras destabilizer, targeting the Wnt/ß-catenin pathway and inhibiting development of metastatic colorectal cancer

Novel inhibitor of the Wnt/ß-catenin pathway, binding directly to the regulators of G-protein signaling domain of axin, initiating ß-catenin and Ras degradation through enhancement of the ß-catenin destruction complex activating GSK3ß, effectively suppres

Selective T-type Ca(2+) channel blocker with anti-proliferative effects against various cancer cells

Potent inhibitor of LpxC and lipid A biosynthesis

Nonpeptide agonist of angiotensin AT1 receptor

Novel cell-permeable attenuated cationic amphiphilic lytic (ACAL) peptide, efficiently bring immunoglobulin G (IgG) and other functional proteins into cells

Novel Migration Inhibitory Factor (MIF) inhibitor, binding at the allosteric and tautomerase sites, blocking MIF's tautomerase CD74 receptor binding, and pro-inflammatory activities

Novel γ-secretase modulator photoaffinity probe, identifying distinct allosteric binding sites on presenilin that can be exploited to reduce levels of pathogenic Aβ species

Novel inhibitor of α-synuclein amyloid aggregation for the treatment of Parkinson's disease

Novel inhibitor of the TWEAK-Fn14 signaling cascade

Novel potent inhibitor of human pancreatic cancer cells

Potent leukotriene inhibitor