Novel Peptide Deformylase Inhibitor against Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus

Novel Modulator of autoimmune demyelination

Potent inhibitor of histone deacetylase

Novel, potent and selective CRTh2 antagonist

Natural fungal phytotoxin, activating the plant jasmonic acid pathway

Lipopeptide antibiotic with activity against a range of Gram-positive bacteria including drug-resistant pathogens

Novel dual TRPV1 antagonist and TNF-alpha production inhibitor

Novel adenosine receptor agonist, inducing relaxation of corpus cavernosum; Novel selective phosphodiesterase-​4 (PDE4) inhibitor associated with anti-​TNF-​α properties

Novel Adenosine A2a Receptor Agonist, Attenuating the Progression of Monocrotaline-induced Pulmonary Hypertension

Novel IKK-β inhibitor, reducing the secretion of TNF-α, IL-1β, IL-6, IL-12, IFN-γ and increased secretion of IL-10, protecting gastrointestinal homeostasis

Novel orally active IKK2 inhibitor

Novel Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitor

Natural F508del-CFTR corrector, inhibiting both PARP-3 and -16, regulating the activity of the unfolded protein response activator inositol-requiring enzyme (IRE-1) via modulation of the level of its ribosylation by PARP-16

Natural F508del-CFTR trafficking corrector, targeting poly(ADP-ribose) polymerase (PARP)

Disruptor of microfilament-mediated processes

Microtubule stabilzer, potently inhibiting cellular proliferation in cancer cell lines

Natural antifungal and cytotoxic agent

Natural inhibitor of the proliferation of sensitive and resistant human cancer cell lines and this inhibitory activity is strongly increased in the presence of laxaphycin A

Potent, orally active, selective and direct thrombin inhibitor

Prodrug of LB30870 as potent, orally active, selective and direct thrombin inhibitor

Neurotoxic amino acid

Novel antibiofilm coating, covalently bindng to a titanium implant surface (LC0024-Ti)