Antibacterial agent, with a relatively narrow spectrum against bacteria and a very high CC 50 value

Novel specific inhibitor of HA-mediated viral entry, inhibiting HPAI H5N1 virus strain A/Hong Kong/H5N1

Topical nonnucleoside reverse transcriptase inhibitor, partially preventing vaginal RT-SHIV infection of macaques

Potent and HDAC class I-selective inhibitor

Novel potent acetylcholinesterase (AChE) inhibitor

The first inhibitor of forkhead Box Protein C2 (FOXC2)

Novel selective PARP1 inhibitor, inhibitng apoptosis and blocking poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells

Novel hybrid retinoid-HDAC inhibitor

Potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively)

Novel neurotropic agent

Specific and highly fluorescent substrate for caspase-1, also acting as a substrate for caspase-4

Novel selective inhibitor of the Polo-box domain of Polo-like kinase 1 (PLK1)

First-in-class inhibitor of MFS efflux pump CaMdr1p

Novel inverse agonist for the pancreatic-type ATP-sensitive K channel as vascular relaxing agent

Potent and selective inhibitor of NLRP3, reducing interleukin-1β (IL-1β) production in vivo and attenuating the severity of experimental autoimmune encephalomyelitis (EAE)

Albumin-binding prodrug of Doxorubicin

Novel potent F508del-CFTR corrector, modulating poly-ADP ribose polymerase 3 and poly-ADP ribose polymerase 16 activities

Selective NA reuptake inhibitor with 5-HT3 receptor antagonism

Novel inhibitor of p53-MDM2 interaction

Novel potent and selective degrader of Mcl-1

Novel reversible covalent inhibitor for Mcl-1 with improved water solubility than Mcl-1 Inhibitor-5

Novel selective Mcl-1 inhibitor