MAO-B inhibitor and glycine prodrug, being studied for treatment for the symptoms of Alzheimer's disease

Natural anti-tumor agent, demonstrating with tumor inhibitory efficacy comparable or even superior to the mainstay chemotherapeutics paclitaxel or fluorouracil

First-in-class inhibitor of MYC-induced nuclear antigen (MINA53) with selectivity over NO66 and other JmjC oxygenases

Inhibitor of cholecystokinin B receptors (CCK2)

Novel inhibitor of the prostate-specific membrane antigen (PSMA)

Novel inhibitor of the prostate-specific membrane antigen (PSMA)

Novel long-lasting myostatin inhibitor, significantly increasing muscle mass and hindlimb grip strength in Duchenne muscular dystrophic model mice

Novel photoactivatable allosteric ligand for the M1 muscarinic acetylcholine receptor

Novel selective positive allosteric modulator (PAM) at the M1 muscarinic acetylcholine receptor

Novel thapsigargin-based PSMA-activated prodrug, inhibiting the sarcoplasmic/endoplasmic reticulum calcium adenosine triphosphatase (SERCA) pump protein

Novel specific and efficient inhibitor of miR-21 expression, inducing a 485% increase in the luciferase reporter signal at 10 μM

Novel inhibitor of microRNA-21 (miR-21)

Novel Miro1 degrader, rescuing dopaminergic neurodegeneration and promoting Miro1 degradation in Parkinson’s Disease fibroblasts

Novel degrader of Miro1 (mitochondrial Rho GTPase 1), reducing Miro1 levels in fibroblasts and stress-induced degeneration of dopaminergic neurons derived from Parkinson's disease (PD) patients, as well as age-dependent neuronal loss and prolongs lifespan

Novel inhibitor of AMA1-RON2 interaction, blocking merozoite invasion from schizont-infected RBCs; Antidepressant; Acetylcholinesterase inhibitor

The first small molecule inhibitor of Mitf-E-box DNA binding with depigmenting activity

Sensitive and specific Raman probe for live cell imaging of mitochondria

Fluorescent probe for measuring the activity levels of erasers of S-palmitoylation, acyl-protein thioesterases (APTs), within mitochondria of live cells

Radiation Mitigator, reducing lipid hydroperoxides and preventing apoptotic cell death

Novel mitochondrial-targeted pan-APT inhibitor

Novel potent antiproliferative mitochondria-targeted OXPHOS inhibitor (IC50=38 nM) in MiaPaCa-2 cells, being more effective than other inhibitors of OXPHOS in MiaPaCa-2 and U87MG cells

Novel selective fluorescent H2O2 probe, tracking the mitochondria of live biological specimens and responds to local fluxes of hydrogen peroxide (H2O2) by a turn-on fluorescence enhancement