Near-infrared cyanine dye, acting as an optical imaging agent

Novel photodynamic antitumor agent

Novel tyrosinase inhibitor, showing concentration-dependent inhibitory effects with no significant cytotoxicity in cell viability assay

Novel potent HDAC inhibitor, possessing potent anticancer activities

Novel potent histone deacetylase (HDAC) inhibitor, inducing apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells

Novel topoisomerase II inhibitor, markedly inducing apoptotic cell death via the mitochondria-mediated intrinsic pathway in LNCaP cells

Novel tyrosinase inhibitor, down-regulating of MITF and tyrosinase through direct tyrosinase inhibition

Novel sensitizer of cancer cells, significantly increasing DNA damage as determined by DNA breakage, levels of damage-responsive proteins, and DNA foci

Novel inducer of G2/M phase arrest in the cell cycle progression, resulting in growth inhibition and induction of apoptosis in a concentration-dependent manner, and inhibition of proliferation in a time-dependent manner

Novel inhibitor of nitric oxide-induced melanogenesis, targeting the NO-induced cGMP signaling pathway

Novel tyrosinase inhibitor, directly inhibiting mushroom tyrosinase

Novel tyrosinase inhibitor, suppressing UVB-induced activation of NF-κB signaling pathway through the downregulation of oxidative stress

Novel Chemically Stable, Potent, and Efficacious MDM2 Inhibitor

Novel inhibitor of TMPRSS2, also strongly preventing SARS-CoV-2 multiplication and CPE in Calu-3 cells in a dose-dependent manner. causing strong inhibition of SARS-CoV-2 replication

Novel MDM2 antagonist, restoring p53 functions and increases the life span of orally treated follicular lymphoma bearing animals

Novel matriptase-1/matriptase-2 (MT-1/2) inhibitor, also inhibiting TMPRSS2, proteolytic activation and multiplication of influenza A virus in Calu-3 cells

Highly Potent and Efficacious MDM2 Inhibitor

Novel inhibitor of microtubule assembly, inducung mitotic arrest and apoptosis of MM cells

Novel Potent MIF Degrader

Immunomodulator, regulating the activation of monocytes and macrophages, upregulating the secretion of pro-inflammatory cytokines such as TNF-alpha, IL-1, IL-8, nitric oxide and prostaglandins E2 and D2

Novel inhibitor of Migration-Inducting Gene 7 (MIG-7) expression, suppressing EOC cell growth and VEGFA expression

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