Novel potent dual inhibitor of mTOR and HDAC1

Novel selective inhibitor of mTORC1, yielding potent inhibition of glucose uptake

Novel selective mTORC1 inhibitor, directly targeting class I glucose transporters

Novel mTOR inhibitor, exhibiting potent anticancer activities against four tumor cell lines, including MCF-7, HeLa, MGC-803, and C6, inducing cell death via apoptosis by targeting both mTORC1 and mTORC2 within cells and arrests the cell cycle of HeLa at t

Novel mitochondria-targeted photoactivatable real-time probe, being phototriggered by either UV (one-photon) or NIR (two-photon) light to form a fluorescent coumarin product and facilitate the release of drug payload

Useful probe in the mapping of membrane proteins, such as ion channels and transports proteins, as well as enzymes and receptors.

Useful probe in the mapping of membrane proteins, such as ion channels and transports proteins, as well as enzymes and receptors.

Novel potent multitarget ligand

Novel potent MurA inhibitor

Novel potent and selective MCL-1 inhibitor

Novel potent mutant IDH1 R132H inhibitor

Novel potent and selective cathepsin K (Cat K) inhibitor

CNS-penetrant, selective restorer of injury- or disease-induced overproduction of proinflammatory cytokines towards homeostasis. Selective suppressor of beta amyloid (Aβ)-induced glia proinflammatory cytokine production

Novel GPR119 agonist with Anti-Diabetic Efficacy in db/db Mice

Novel mitophagy activator

Major thiol in most actinomycetes involved in mycothiol biosynthesis and mycothiol-dependent enzymes such as mycothiol-dependent formaldehyde dehydrogenase and mycothione reductase

Novel inhibitor of the protein-protein interactions between the bHLHZip proteins c-Myc and Max

Novel inhibitor of the protein-protein interactions between the bHLHZip proteins c-Myc and Max

Novel inhibitor of zinc finger DHHC domain-containing (zDHHC) enzymes

Myotoxin II fragment

Novel potent, reversible and uncompetitive inhibitor of actin-stimulated ATPase activity of myosin V

Novel inducer of apoptosis in a Myc-dependent manner, inhibiting Myc-driven transformation and disrupting MYC-Max interaction