Inhibitor of the chaperonin activity of HSP60, correlating to LONP and LRP130 aggregation

Bacterial RNA polymerase (RNAP) inhibitor

Novel potent and selective PROTAC degrader of BRD3/4

Competitive inhibitor of both SPHK1 and SPHK2

Glucokinase activator (GKA)

Novel RNA labeling probe through both metabolic and enzyme-assisted manners

Deuterium labeled m6A used in important m6A physiological pathways related studies

Alkylating agent, forming DNA adducts at the C-8 position in guanine, resulting in single strand breaks, demonstrating carcinogenic action

Delta-9-tetrahydrocannabinol (THC)/cannabidiol (CBD) combination for the treatment of multiple sclerosis (MS)-related moderate to severe spasticity

Derivative of loline

Novel antiviral agent against the replication of influenza virus A/H3N2 subtype in Madin-Darby canine kidney (MDCK) cells

Coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage

Electron donor and cofactor for many redox enzymes including nitric oxide synthetase

Partial estrogen antagonist, inhibiting angiogenesis in some tissues by blocking the effects of fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF), inducing oxidative stress, protein kinase C and calcium signaling

Novel potent full agonist for orexin receptor

Novel highly selective antibacterial agent against Propionibacterium acnes

Mixed agonist/antagonist opioid modulator, binding with high affinity to the MOR and KOR, and having relatively low affinity for the DOR

Novel fluorescent probe for detection of endogenously produced Naph-O2˙– in living cells and tissues

Novel repeat-structure-specific DNA ligand, specifically binding slipped-CAG DNA intermediates of expansion mutations

Triple reuptake inhibitor

Novel Gut-Restricted Inhibitor of Intestinal Sodium-Dependent Phosphate Transport Protein 2b (NaPi2b) for the Treatment of Hyperphosphatemia

Antagonist of alpha-2 adrenergic receptors and inhibitor of the neuronal uptake of norepinephrine