Potent and selective inhibitor for gelatinases, matrix metalloproteinase 2 (MMP2) and matrix metalloproteinase 9 (MPP9)

Inhibitor of Phosphodiesterase (PDE)-2

Precursor for radiolabeled diltiazem

Major metabolite of loperamide, also used as the precusor for radiolabelled loperamide

Novel G4-DNA ligand, promoting transcription in Gram-positive bacteria and repressing transcription in Gram-negatives

Novel Inhibitor of New Delhi Metallo-β-lactamase-1 (NDM-1)

Negative control compound for Necrostatin-1 related assays

Novel necroptosis inhibitor

Novel inhibitor of caspase-independent cell death with necrotic morphol, distinctly different from apoptosis, autophagy, and necroptosis, displaying strong mitochondrial reactive oxygen species and ONOO- scavenging activity

Non-narcotic analgesic for the relief of acute and chronic pain

Novel Inhibitor of DNA Glycosylases, inhibiting NEIL1 activity

Novel ATP-competitive inhibitor of Nek2 and Nek7

Natural inhibitor of tumor metastasis by upregulating the RNA-binding-protein MBNL2, inducing cell cycle arrest through multiple signaling pathways including RNA binding protein CELF6

Inhibitor of the formation of

Potent natural anti-tumor agent against metastatic colorectal cancer, resulting in cell cycle arrest at the G2/M phase and inducing apoptosis through the dysfunction of mitochondria to trigger intrinsic apoptotic pathway by untargeted metabolomic method,

Natural inducer of autophagy and apoptosis, inhibiting glutamate overexcitation and upregulation of the Wnt/β-catenin signaling pathway

Novel AR inhibitor, being selective for the testosterone stimulated AR-dependent prostate cancer cell

The first potent NAD-driven small molecular inhibitor of TcGAPDH (Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase)

Novel non-peptidic, non-covalent cruzain inhibitor

Human B-type natriuretic peptide, facilitating cardiovascular fluid homeostasis through counterregulation of the renin-angiotensin-aldosterone system, stimulating cyclic guanosine monophosphate, leading to smooth muscle cell relaxation

Anti-inflammatory, antibronchospastic agent

Novel dual Rho Kinase and norepinephrine transporter (ROCK/NET) inhibitor