Novel inhibitor of human cathepsin L

Novel inducer of differentiation in all six AML cell lines

Novel sulindac derivative; anti-inflammatory and anti-cancer agent

Vasodilator and β-adrenoreceptor agonist

Antagonist of cell-surface heparan sulfate and heparin-protein interactions, reducing tau hyperphosphorylation and mitigating or delaying neuronal defects in tauopathies, including Alzheimer's disease

Synthetic hormone with anabolic and androgenic properties

δ-Opioid receptor agonist

Novel p18(INK4C) inhibitor

Novel INK4C inhibitor, specifically blocking the bioactivity of p18 protein

Novel INK4C inhibitor, specifically blocking the bioactivity of p18 protein

Novel INK4C inhibitor, specifically blocking the bioactivity of p18 protein

Second-generation active site-targeted covalent irreversible inhibitor of USP7

Novel potent inhibitor of mTOR activity, significantly suppressing macroscopic and histologic abnormalities associated with chemically-induced murine ulcerative colitis.

Novel P2Y1 Antagonist

Selective spleen tyrosine kinase (SYK) inhibitor, suppressing leukocyte immune function and inflammation, and leading to a reduction in arthritis score and attenuated histological damage

Novel modulator of p53 activity, arresting at G2/M phase inducing delay of cell cycle progression

Novel reactivator of mutant p53, fuctioning as a zinc metallochaperone (ZMC) with diminished copper binding that functions as a chemotherapy and radiation sensitizer

Novel inhibitor of atherogenesis and diabetes, significantly and specifically inhibiting αD-CEP binding

Novel bFGF antagonist peptide, inhibiting breast cancer cell growth

Neuroprotective agent, protecting ventral horn spinal cord motor neurons from cell death

Novel potent inhibitor of the AAA+ ATPase p97

Novel potent inhibitor of the AAA+ ATPase p97