Novel inhibitor of β-catenin signaling, significantly reduced β-catenin activity in hepatoblastoma and several HCC cells

Novel potent irriversible dual inhibitor of tubulin and epidermal growth factor receptor (EGFR), inducing the apoptosis of A549 cells in a dose- and time-dependent manner, along with decrease in mitochondrial membrane potential (MMP), production of ROS an

Novel inhibitor of prenylated methylated protein methyl esterase (PMPMEase), a key enzyme in the reversible methylation/demethylation step in the protein prenylation pathway

Novel inhibitor of prenylated methylated protein methyl esterase (PMPMEase), a key enzyme in the reversible methylation/demethylation step in the protein prenylation pathway

Selective 5-HT1A serotonin receptor antagonist

Cell-permeable analog of pifithrin-α, potently blocking p53-mediated expression of p21/WAF1 and apoptosis

Novel G Protein-Biased Cannabinoid 1 (CB1) Receptor Agonist

Potent inhibitor of CDK2/cyclin A

Allosteric modulator of 5-HT(2C)R with no intrinsic agonist activity

The first small-molecule approach capable of detecting and controlling engineered cell-cell outputs

Novel microtubule destabilizing natural product from the Podophyllum species

Novel RNA polymerase I inhibitor, targeting ribosomal DNA G-quadruplexes, potently and selectively inhibiting cell growth by high-affinity binding to G4s in ribosomal DNA, impairing RNA polymerase I (Pol I) elongation, inducing a rapid inhibition of Pol I

Novel macrocycle antibiotic with selective and potent activity against P. aeruginosa

Novel modulator of protein-protein interactions of the mitotic polo-like kinases, targeting KRAS mutant xenografts, indicate avenues, acting synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells

Pan-Specific Inhibitor of the Polo-Box Domains of Polo-like Kinases Arrests Cancer Cells in Mitosis

Used for the transfection of a broad variety of cell lines; Antimicrobial; Novel binding agent of diffusive gradients in thin-films (DGT) technique (PEI-DGT)

Novel activator of Adenosine monophosphate (AMP)-activated protein kinase (AMPK)

Antibiotic as a last-line therapy to treat infections caused by these life-threatening 'superbugs'

Novel pan-inhibitor of KCa3.1/KCa2 channels

Potent Activator of Vγ9Vδ2 T-Lymphocytes; HMBPP ananlog prodrug

Hypobetalipoproteinemic and Lipid decreasing agent

Novel pan-human EGF receptor (HER) inhibitor