Inhibitor of the acetylcholinesterase activity from bovine erythrocytes and electric eel

Inhibitor of topoisomerase II, intercalating into DNA and inducing topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity

Potent ligand to target the Y220C pocket, stabilizing Y220C

Novel Protein Kinase C-iota (PKC-ι) Inhibitor, Binding Post-kinase Domain Residues

Novel selective inhibitor of protein kinase Cθ (PKCθ)

Novel highly potent and selective PKM2 inhibitor, blocking PKM2 mitochondrial translocation under nutritional stress and inhibits tumor growth in vivo

Novel potent and specific β5i inhibitor

Potent inhibitor of HipA toxin, inhibiting E. coli persistence

mRNA splicing inhibitor

Antilipidemic and antiplatelet agent

Novel Potent and Specific Inhibitor of Placental Alkaline Phosphatase (PLAP; IC 50 = 32 nM), Targeting Tumor of the Female Reproductive Tract

Novel Potent Activator of the Nonreceptor Protein Tyrosine Phosphatase Shp2

Gastroprotective agent, increasing the prostaglandin production in the gastric mucosa and accelerates ulcer healing

Broad spectrum aminoglycoside antibiotic typically used for moderate-to-severe urinary tract infections or pyelonephritis

Novel inhibitor of phospholipase C (PLC) isozyme

Novel enhancer of Reactive Oxygen Species (ROS), depleting glutathione levels in analogy to piperlongumine but with reduced cell death

Novel activator of AMPK, inducing apoptotic death in prostate cancer cells

Plk1 PBD-specific phosphopeptide inhibitor, effectively inhibiting mitotic progression and cell proliferation

Novel Inhibitor of the Polo-Box Domain of Polo-like Kinase 1 (Plk1 PBD)

Novel polo-like kinase 1 (PLK1) inhibitor

Slightly less potent inhibitor of FMS than PLX647 but has better aqueous solubility

Potent anticancer tetrahydroisoquinoline alkaloid, being able to form a covalent bond with the amino group of a guanine in selected triplets of DNA duplexes and eventually give rise to double-strand breaks