Promising pro-apoptotic agent, showing activity on various cancer cell lines

Novel MOR agonist

Novel Fluorescent ER-Tracker dye, showing potent cytotoxic activity on several types of cancer cells, being accumulated into the endoplasmic reticulum (ER) as highlighted by its colocalization

The first irreversible covalent MPS1 inhibitor, targeting a poorly conserved cysteine in the kinase's hinge region

Potent, reversible, non-carbonyl inhibitor of fatty acid amide hydrolase (FAAH)

Novel potent and specific RNA-binding ligand, targeting riboswitches and other RNAs at proximal subsites

Selective antagonist of NMDA receptors NR2B subunits

Selective alpha1A/1L-adrenoceptor partial agonist

Potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit

Potent protein kinase C (PKC) inhibitor

ADAM17-selective inhibitor

Competitive AMPA receptor antagonist

Selective, non-competitive Metabotropic_glutamate_receptor>mGlu2 antagonist

Novel NR2B selective, non-competitive, voltage-independent antagonist

NMDA receptor antagonist , specifically suppressing the severe autoimmune phenotypes of chs3-2D (chilling sensitive 3, 2D), including the arrested growth morphology and heightened PR (Pathogenesis Related) gene expression

Potent and selective Candida albicans N-myristoyltransferase (CaNmt) inhibitor

Potent and selective Candida albicans N-myristoyltransferase (CaNmt) inhibitor, exhibiting antifungal activity in vivo

Vitamin D analogue, showing significant in vitro and in vivo antitumor activity.

Novel reversible inhibitor of interleukin-2 (IL-2)

Dual inhibitor of HDAC and MMP

Potent and selective inhibitor of the p38 MAPK catalytic domain

Beta(1) adrenoceptor-selective agonist