Novel potent SARS-CoV-2 MTase Nsp14 and Nsp16 inhibitor

Selective non-peptide vasopressin V2 receptor antagonist

Selective non-peptide vasopressin V2 receptor antagonist

Novel inhibitor of salmonella serine acetyltransferase (SAT), the enzyme that catalyzes the rate-limiting step of L-cysteine biosynthesis

Inhibitor of H274Y and N294S mutants

Subtype-selective α4β2 nicotinic acetylcholine receptor partial agonist

PPARγ covalent ligand

Novel reversible covalent inhibitor of the cyclin-dependent kinase 5 (Cdk5)-mediated phosphorylation of PPARγ at Ser245, a key factor in the insulin-sensitizing effect of PPARγ-targeted drugs

Novel neuroprotective agent, suppressing abnormal tau protein aggregation

Selective, active-site-directed 14 kDa PLA2 inhibitor, totally inhibiting LT and PAF formation, while prostanoid formation was not altered

Dual ETA and ETB receptor antagonist

Potent, specific inhibitor of human p38 mitogen-activated protein (MAP) kinase

Potent and selective agonist for the human ß3-adrenoceptor

Inhibitor of p38 MAPK

Selective 5-HT2C_receptor>5-HT2C inverse agonist

Selective 5-HT7 receptor antagonist

Novel selective mTOR inhibitor

Nonpeptidic antagonist of alpha(v)beta3 and alpha(v)beta5 integrins, reducing angiogenesis and VEGF expression

Selective dopamine D3 receptor antagonist

Selective p38a kinase inhibitor, inhibiting Brd4

AntiMycobacterium tuberculosis agent

Novel TRPV4 blocker