Potent and selective dopamine D3 receptor antagonist

Novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor

Novel CXCR2 selective antagonist, inhibiting ex vivo neutrophil activation and ozone-induced airway inflammation in humans

Novel inhibitor of mitogen and Stress-Activated Kinases 1 (MSK1)

Novel Rho kinase inhibitor

Potent non-cytotoxic inhinitor of Mycobacterium tuberculosis H37Rv

Novel cAMP-independent potentiator of CFTR, synergistically restoring CFTR function

Novel cAMP-independent potentiator of CFTR, synergistically restoring CFTR function

Membrane-permeant, fluorescent, selective Na+ indicator dye

Novel potentiator of metabotropic glutamate receptors for use against neurological and psychiatric disorders

Novel potentiator of metabotropic glutamate receptors for use against neurological and psychiatric disorders

Novel inhibitor of Quiescin Sulfhydryl Oxidase 1 (QSOX1), suppresses tumor cell growth in a Matrigel-based spheroid assay and inhibits invasion in a modified Boyden chamber, but does not affect viability of non-malignant cells

Inhibitor of S100B which selectively kills melanoma; Amoebicidal diamidine

Novel Smac mimetic, demonstrating potent cell-killing effects in several subtypes of breast, ovarian, and prostate cancer cell lines but only when the DR ligand TRAIL or another such apoptosis inducer is co-administered

Novel obatoclax derivative, inducing apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation

Potent inhibitor of checkpoint kinase 2 (Chk2)

Matrix metalloproteinase (MMP) inhibitor, also acting as a collagenase inhibitor

Second-generation leukotriene B4 receptor antagonist

Selective COX-2 inhibitor

Potent and selective inhibitor of p38 MAP kinase

Novel selective COX-2 inhibitor

Novel photoswitchable substrate for sphingomyelin synthase 2 (SMS2), enabling optical control of apoptosis and being ready for azide-alkyne click chemistry