Allosteric modulator of A3 adenosine receptors

Multidrug resistance inhibitor

Novel Probe of Putative MOR-CCR5 Heterodimers to Inhibit Opioid Exacerbated HIV-1 Infectivity

W-13 hydrochloride is a calmodulin antagonist. W-13 hydrochloride can inhibit Tamoxifen (HY-13757A)-resistant human breast cancer cell growth.

Calmodulin antagonist, inhibiting Ca2+/calmodulin-regulated enzyme activities

Mixed competitive/noncompetitive inhibitor of

Nocel inhibitor of BMI1 promoter activity, decreasing BMI1 protein levels in HCT116 human colon carcinoma cells, significantly reducing levels of the CSC biomarker epithelial cell adhesion molecule and diminishing the self-renewal capability of CSCs

Very late adhesion molecule 4 (VLA-4) antagonist, inhibiting VLA-4/VCAM-1 ligation as a means of modulating eosinophil functions beyond its action on cell adhesion and migration

SGLT2 inhibitor

ATP-sensitive potassium channel opener

Inhibitor of human collagenase-3 (MMP-13)

Potent and selective inhibitor of matrix metalloprotease MMP-13 (Collagenase-3)

Inhibitor of matrix metalloproteinase-1 (MMP-1)

Potent and Selective Inhibitor of the Norepinephrine Transporter

Secreted frizzled-related protein-1 (sFRP-1) modulaitor

Novel inhibitor of The epidermal growth factor receptor (EGFR), decreasing NSCLC cell proliferation and colony formation, by causing G2/M arrest and apoptosis.

Non-peptide GLP-1 receptor agonist, blocking inflammatory nociception by stimulating β-endorphin release from spinal microglia

Novel Inhibitor of PBP2, Showing Potent β-Lactam Enhancer Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones

Highly conserved neuropeptide derived from Chromogranin A (Parathyroid Secretory Protein 1)

Novel very potent and long acting hetrazepinoic PAF-antagonist

Novel inhibitor of type III secretion system ATPase EscN from enteropathogenic Eecherichia coli

Novel fluoroquinolone antibiotic with potent antimicrobial activity, showing the potential to overcome major drug resistance; its antimicrobial activity was less affected by both pump-mediated efflux and QRDR mutations in P. aeruginosa compared with LVX a