Cat. No. | Product name | CAS No. |
DC20450 |
MI-2-2 hydrochloride
MI-2-2 hydrochloride is a potent inhibitor of the menin-MLL interaction that binds to menin with low nanomolar affinity (Kd=22 nM). |
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DC20449 |
MI-2-2
Featured
MI-2-2 is a potent inhibitor of the menin-MLL interaction that binds to menin with low nanomolar affinity (Kd=22 nM); inhibits the interaction of menin with MLL-AF9 in HEK293 cells in a dose-dependent manner with 4-fold potentcy improvement over MI-2; suppresses growth of MLL-AF9–transformed BMCs; causes MV4:11 cells growth inhibition of with GI50 of 3 uM. |
1454920-20-7 |
DC23291 |
MI-223
MI-223 (NSC 320223) is a small molecule that specifically binds to Mcl-1 with Kd of 160 nM, inhibits HR DNA repair and sensitizes cancer cells to DNA replication agents. |
907166-59-0 |
DC11162 |
MID-1
Featured
MID-1 (ChemBridge5655896) is a specific small molecule MG53-IRS-1 interaction disruptor (MID), but not MG53-FAK and-Cav-3 interaction; increases the IRS-1 protein level in C2C12 myotubes, abrogates MG53-induced IRS-1 ubiquitination and degradation; potent |
312608-54-1 |
DC20962 |
Midazolam
Midazolam (Dormicum. |
59467-70-8 |
DC24075 |
Midodrine
Featured
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension. |
42794-76-3 |
DC24076 |
Midodrine hydrochloride
Featured
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension. |
43218-56-0 |
DC20451 |
MIF-IN-3bb
MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM. |
1663475-35-1 |
DC12425 |
MIK665
MIK665 (S-64315, MIK-665) is a novel potent, selective Mcl-1 inhibitor with potential pro-apoptotic and antineoplastic activities. |
1799631-75-6 |
DC3158 |
Milrinone
Featured
Milrinone(Primacor) is a a potent and selective phosphodiesterase 3 inhibitor with an IC50 of 0.42 μM for the inhibition of FIII PDE |
78415-72-2 |
DC21074 |
Milveterol
Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold). |
652990-07-3 |
DC21075 |
Milveterol hydrochloride
Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold). |
804518-03-4 |
DC21584 |
MIN-101
Featured
MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia.. |
359625-79-9 |
DC23395 |
MIND-4
MIND-4 is a novel potent, selective, non-competitive SIRT2 deacetylase inhibitor with IC50 of 1.2 uM, Ki of 2.1 uM, and also is an inducer of the NRF2 pathway. |
1639965-26-6 |
DC11902 |
Minesapride
Minesapride (DSP-6952) is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c. |
1184662-54-1 |
DC21919 |
MIR17PTi
MIR17PTi is a novel LNA gapmeR antisense oligonucleotide (LNA-ASO), first-in-class inhibitor of pri-mir-17-92. |
|
DC11045 |
miR-21 inhibitor 37
miR-21 inhibitor 37 is a novel inhibitor of miR-21 function with EC50 of 5.3 uM in HeLa-miR21-Luc assays, displays no inhibition of miR-122. |
2241028-18-0 |
DC21651 |
miR544-IN-1
miR544-IN-1 (SID 3712249) is a selective small molecule inhibitor of miR-544 biogenesis. |
522606-67-3 |
DC23113 |
Mirk-IN-1
Featured
Mirk-IN-1 is a potent, specific inhibitor of Dyrk1B (Mirk kianse) and Dyrk1A with IC50 of 68 nM and 22 nM respectively, shows SW620 cell IC50 of 1.9 uM. |
1386979-55-0 |
DC20452 |
MitoBloCK 1
MitoBloCK 1 is a small molecule inhibitor that blocks the import of substrates that use the TIM22 import pathway, but not TIM23 or the Mia40/Erv1 translocation pathways. |
373370-73-1 |
DC12625 |
MitoBloCK-10
Featured
MitoBloCK-10 (MB-10) is a potential attenuator of protein import into mitochondria via targeting Tim44, inhibits the import of substrates that use the TIM23 import pathway. |
394694-98-5 |
DC12626 |
MitoBloCK-11
Featured
MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development. |
413606-16-3 |