Cat. No. | Product name | CAS No. |
DC21924 |
mutant IDH1 inhibitor VVS
mutant IDH1 inhibitor VVS is a potent, selective mutant IDH1 inhibitor with nanomolar potency against both IDH1 R132H and IDH1 R132C, efficiently suppresses the cell-based production of D-2-HG in an HEK293 mutant embryonic kidney cell line.. |
1648909-73-2 |
DC20258 |
MW150 (MW01-18-150SRM)
MW150 (MW01-18-150SRM) is a selective, brain penetrant p38αMAPK, which is efficacious in diverse animal models of neurologic disorders. |
|
DC11829 |
MW-150
Featured
MW-150 is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM |
1628502-91-9 |
DC11828 |
MW-150 hydrochloride
MW-150 is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM |
1923773-01-6 |
DC21355 |
MW181
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ. |
1454658-87-7 |
DC21356 |
MW181 dihydrochloride
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ. |
1628503-08-1 |
DC21357 |
MW181 hydrochloride
MW181 (MW01-10-181SRM) is an isoform-selective, brain-permeable, and orally bioavailable small molecule inhibitor of p38α MAPK with Ki of 184 nM, no affitnity for CK1δ. |
1454658-90-2 |
DC22170 |
MX106
MX106 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 2.2 uM. |
2170836-81-2 |
DC22171 |
MX107
MX107 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 3.1 uM. |
2170102-50-6 |
DC21925 |
MY10
MY10 is a small-molecule inhibitor of RPTPβ/ζ (PTPRZ1) with IC50 of 0.1 uM, significantly increases the phosphorylation of key tyrosine residues of RPTPβ/ζ substrates involved in neuronal survival and differentiation. |
2204270-73-3 |
DC21926 |
MY33-3
MY33-3 is a small-molecule inhibitor of RPTPβ/ζ (PTPRZ1) with IC50 of 0.1 uM, significantly increases the phosphorylation of key tyrosine residues of RPTPβ/ζ substrates involved in neuronal survival and differentiation. |
2204280-41-9 |
DC10952 |
MYCMI-6(NSC 354961)
Featured
MYCMI-6 (NSC354961) is a selective, high affinity inhibitor of MYC-MAX interaction, blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with Kd of 1.6 uM in SPR assay. |
681282-09-7 |
DC21927 |
Myokinasib
Myokinasib is a mixed-type, selective inhibitor of Myosin Light Chain Kinase 1 (MLCK1) with IC50 of 7.9 uM, can bind to the free enzyme and the enzyme-substrate complex. |
|
DC20469 |
myomiRs-IN-1
myomiRs-IN-1 is a small-molecule probe that selectively inhibits myogenic microRNAs (myomiRs) including miR-1, miR-133a, and miR-206. |
1392224-59-7 |
DC21360 |
MZ1
Featured
MZ1 is a PROTAC that tethers JQ1 to a ligand for the E3 ubiquitin ligase VHL, triggers, induces degradation of the BET bromodomain BRD4. |
1797406-69-9 |
DC22172 |
MZH29
MZH29 is a novel potent, selective, orally active type II FLT3 inhibitor with IC50 of 9 nM and 7 nM against FLT3-WT and FLT3-ITD, respectively. |
2089590-80-5 |
DC8428 |
Lomitapide Mesylate
N-(2,2,2-trifluorethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide methanesulfonate |
202914-84-9 |
DC23254 |
N.41
N.41 (HIV inhibitor N.41, Vif inhibitor N.41) is a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G (A3G) protein (IC50=2.2 uM). |
357441-99-7 |
DC21107 |
N1-hexyl-N5-benzyl-biguanide mesylate
N1-hexyl-N5-benzyl-biguanide mesylate (HBB) is a potent and specific inhibitor of CYP3A4 AA epoxygenase activity with IC50 of 9.5 uM for inhibition of CYP3A4-mediated (±)-14,15-EET synthesis. |
1834584-89-2 |
DC10359 |
N2-Methylguanine
N2-Methylguanine is a modified nucleoside. N2-Methylguanine is an endogenous methylated nucleoside found in human fluids. |
10030-78-1 |
DC9543 |
N3PT
N3PT(N3-pyridyl thiamine) is a potent and selective transketolase(TK) inhibitor (IC50= 22 nM for Apo-TK) both in vitro and in vivo. |
13860-66-7 |
DC10154 |
N6-(2-Phenylethyl)adenosine
N6-(2-Phenylethyl)adenosine is a selective A1 adenosine receptor agonist. |
20125-39-7 |