Cat. No. | Product name | CAS No. |
DC23617 |
NAB-14
Featured
NAB-14 is a potent, selective negative allosteric modulator of GluN2C/2D-containing NMDA receptors with IC50 of 580 nM, >800-fold selective over GluN2A/GluN2 receptors; inhibits triheteromeric (GluN1/GluN2A/GluN2C) NMDARs with modestly reduced potency and efficacy compared to diheteromeric (GluN1/GluN2C/GluN2C) receptors; inhibits GluN2D-mediated synaptic currents in rat subthalamic neurons and mouse hippocampal interneurons, but has no effect on synaptic transmission in hippocampal pyramidal neurons. |
1237541-73-9 |
DC21358 |
N-acetyl lysyltyrosylcysteine amide
Featured
N-Acetyl lysyltyrosylcysteine amide is a potent, reversible, specific, and non-toxic tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide effectively inhibits MPO generation of toxic oxidants in vivo. N-Acetyl lysyltyrosylcysteine amide reduces neuronal damage and preserves brain tissue and neurological function in the stroked brain. N-Acetyl lysyltyrosylcysteine amide inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL oxidation. |
1287585-40-3 |
DC23924 |
N-Acetyl-Calicheamicin
Featured
N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic. |
108212-76-6 |
DC20470 |
NAcM-COV
NAcM-COV is a specific, irreversible small molecule inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 with IC50 of 28 nM in TR-FRET assays. |
2089293-81-0 |
DC20038 |
NAcM-OPT
NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction. |
2089293-61-6 |
DC21444 |
Nacubactam
Featured
Nacubactam (OP 0595, RG 6080, RO 7079901) is a diazabicyclooctane that inhibits class A and C β-lactamases with IC50 of <1 uM, also acts as a PBP2-active antibacterial. |
2007923-17-1 |
DC9619 |
Nafamostat (mesylate)
Featured
Nafamostat mesylate, a synthetic serine protease inhibitor, is an anticoagulant,showed highly potent activity against COVID-19(SARS-COV-2). |
82956-11-4 |
DC23132 |
Nalfurafine hydrochloride
Featured
Nalfurafine (TRK-820, TRK820) is potent, selective agonist of kappa-opioid receptor with Ki of 3.5 nM, 15-fold less potent for μOR and little affinity for δOR (Ki=53 and 1,200 nM, respectively). |
152658-17-8 |
DC23102 |
Nalfurafine
Featured
Nalfurafine (TRK-820, TRK820) is potent, selective agonist of kappa-opioid receptor with Ki of 3.5 nM, 15-fold less potent for μOR and little affinity for δOR (Ki=53 and 1,200 nM, respectively). |
152657-84-6 |
DC9787 |
NAMI-A
NAMI-A is a ruthenium anticancer agent and a metastasis inhibitor. |
201653-76-1 |
DC20031 |
NAMPT inhibitor-linker 1
NAMPT inhibitor-linker 1 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-3 consists of an NAMPT inhibitor-linker 1 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressin |
2241019-57-6 |
DC20032 |
NAMPT inhibitor-linker 2
NAMPT inhibitor-linker 2 is a drug-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-4 consists of an NAMPT inhibitor-linker 2 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressin |
2241014-82-2 |
DC22632 |
NAN-190 hydrobromide
NAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM. |
115338-32-4 |
DC10228 |
Nandrolone
Nandrolone is a synthetic, anabolic steroid analog of testosterone. |
434-22-0 |
DC22531 |
Naquotinib
Naquotinib (ASP-8273) is a potent, irreversible, mutant-selective inhibitor of EGFR (IC50=8-33 nM for (L858R, exon 19 deletion, L858R/T790M, and del19/T790M)). |
1448232-80-1 |
DC22526 |
Naquotinib mesylate
Naquotinib (ASP-8273) is a potent, irreversible, mutant-selective inhibitor of EGFR (IC50=8-33 nM for (L858R, exon 19 deletion, L858R/T790M, and del19/T790M)). |
1448237-05-5 |
DC20700 |
Naronapride
Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM. |
860174-12-5 |
DC21361 |
N-aryl benzimidazole
N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells.. |
422554-26-5 |
DC23157 |
Naspm trihydrochloride
Featured
Naspm is a selective antagonist of Ca2+-permeable AMPA receptors, blocks GluR2-lacking AMPARs, suppresses current responses induced by kainate in type II neurons with IC50 of 0.33 uM. |
1049731-36-3 |
DC9341 |
Naspm
Featured
Naspm(1-Naphthylacetyl spermine) is a potent and selective Ca2+ permeable AMPA receptor(Ca-perm AMPAR) blocker. IC50 value: Target: CP-AMPAR blocker Naspm is a selective blocker of Ca(2+)-permeable GluA2-lacking AMPA receptors, reduced MNNG-induced CA1 |
122306-11-0 |
DC8666 |
Nav1.7-IN-2
Nav1.7-IN-2 is an inhibitor of voltage-gated sodium channels (Nav), in particular Nav 1.7, with IC50 of 80 nM. |
1332295-35-8 |
DC20025 |
Nav1.7-IN-3
Nav1.7-IN-3 is a selective, orally bioavailable voltage-gated sodium channel Nav1.7 inhibitor with an IC50 of 8 nM. Pain relief. Limited CNS penetration. |
1788872-06-9 |