Novel TLR2 agonist, promoting cross-presentation by mouse and human antigen presenting cells

Novel highly hydrophilic and non-ATP-competitive MEK1/2 inhibitor

Selective, direct-acting covalent inhibitor of the K-Ras G12C mutant relative to wild-type Ras

Novel Active Site Inhibitor of Oncogenic K-Ras G12C

Novel Stablizer of Survival of Motor Neuron 2 (SMN2) , Post-Translationally Stablizing SMN Protein for the Treatment of Spinal Muscular Atrophy (SMA)

Novel specific splicing enhancer, targeting RNA for a specific splicing correction, recognizing the interface between U1 snRNP and the SMN2 E7 5ʹ SS, promoting the U1-C zinc finger RNA duplex binding activity

Second-generation modulator of utrophin, increasing utrophin expression in skeletal, respiratory and cardiac muscles

Novel dual inhibitor of thrombolysis and soluble epoxide hydrolase

Novel Smurf1 inhibitor, promoting bone formation in mouse models of distinctive age-related osteoporosis

Novel potent TLR1/2 Specific Agonist, Suppressing Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes

Selective ligand of GC-rich sequences in DNA

Novel potent DNA-binding topoisomerase II-directed antitumor agent.

Novel specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188)

Novel Bioorthogonal Prodrug of SN-38 with Fast Reaction Kinetics and High Releasing Efficiency In Vivo

Potent and selective GAL3 antagonist

Highly selective alpha1A-adrenoceptor antagonist

Specific and Nongenetic IAP-dependent Protein Eraser (SNIPER), acting as a protein degradation inducer of oncogenic BCR-ABL protein

Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Eraser (SNIPER), acting as a a protein degradation inducer of bromodomain-containing protein 4 (BRD4)

Novel fused proteins degrader of the His-tagged CRABP-II and Smad2 in cells

Novel potent degrader of the mitochondrial CRABP-II protein

Novel potent and selective degrader of the ERα protein

Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Eraser (SNIPER), acting as a a protein degradation inducer of phosphodiesterase-4 (PDE4)