COX/5-LOX inhibitor and cytokine-modulating anti-inflammatory agent

Peptide vaccine, residues (611-626) of the human telomerase reverse transcriptase catalytic subunit (hTERT), for the treatment of solid cancers

Selective Thromboxane_receptor>thromboxane receptor antagonist

Mutually Orthogonal Bioorthogonal Amino Acid, Enabling Efficient Protein Dual-Labeling in Cells

Reversible inhibitor of vesicular monoamine transporter 2, showing anti-chorea effect and decreasing uptake of monamines into synaptic vesicles, as well as depletion of monoamine storage

Activator of the hepatic interferon pathway in rats

Potent inhibitor of protein synthesis, inhibiting translation by binding within the ribosomal exit tunnel

Inducer of S phase arrest and apoptosis in hepatocellular carcinoma QGY-7701

Antitubercular agent

Potent and selective human leukocyte 5-lipoxygenase (5-LOX) inhibitor

Novel endothelin (ET) receptor antagonist

Novel multipotent anti-Alzheimer agent, selectively inhibiting human butyrylcholinesterase (BChE), having strong antioxidant activity and good β-amyloid (Aβ) anti-aggregation properties

Novel GSK-3β inhibitor, showing anti-neuroinflammatory effects in lipopolysaccharide (LPS) activation of spontaneously immortalized SIM-A9 microglial cells and of mouse cortical microglia, inhibiting LPS-induced production of nitric oxide and the proinfla

Novel cell-active, selective class IIa HDAC inhibitor

CNS-penetrant selective class IIa histone deacetylase (HDAC) inhibitor, exploiting the >100-fold selectivity over class I/IIb HDACs

Cyclized tamoxifen analog, selective ER modulator (SERM)

Novel and Potent Stem Cell Mobilizer; Inhibitor of SDF-1α/CXCR4 binding

Novel potent SARS coronavirus (CoV) 3CL protease inhibitor (Ki = 53 nM)

Novel dual VEGFR/Src kinase inhibitor

Novel inhibitor of T315I mutant enzyme, exhibiting reasonable in vivo efficacy in a xenograft mouse model harboring T315I

Novel, Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist

Novel inhibitor of mitochondrial calcium uptake (#333333; font-family: "Open Sans", HelveticaNeue, "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 15px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: