Highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (TG2) inhibitor

EP2 allosteric potentiator

Potent and selective nociceptin opioid receptor (NOP) agonist

Potent and selective nociceptin opioid receptor (NOP) agonist

Potent and selective nociceptin opioid receptor (NOP) agonist

Potent and Selective Antagonist for Human EP2 Receptors

Novel potent and structure-specific inhibitor of pre-miR-200c, reversing a type 2 diabetes phenotype

Novel potent TGR5 agonist, displayind a significant glucose-lowering effect and stimulated GLP-1 and insulin secretion in TGR5H88Y mice but not in wild-type animals

Novel Potent Agonist of TGR5 Receptor

Cell-permeable, potent, and selective inhibitor of PI 3-K isoforms p110ß/p110d

Potent and selective inhibitor of PI 3-K

Novel highly potent and specific inhibitor of TLR8, targeting an unconventional pocket on the TLR8 protein-protein Interface

Natural potent human carboxylesterase 2 (hCES2) inhibitor (IC50: 5.05 μM)

Natural antibiotic, being active against P. aeruginosa both in vitro and in vivo.

Novel glutaminase activity inhibitor, showing a partial uncompetitive inhibition in vitro and a significant reduction of ammonia and glutamate production in vivo

Prodrug of Thiamphenicol, inhibiting the 50S subunit of the bacterial ribosome and protein translation

Novel antibiofilm agent, disturbing symbiotic balance between C. albicans and S. mutans in dual species biofilm

Highly efficient bioregulator of plant morphogenesis in the tissue culture technique, inducing diverse responses ranging from induction of callus to embryogenesis or organogenesis, acting through modulation of the endogenous plant growth regulators, modif

Novel protein-protein interaction inhibitor of PAC3 homodimer

Novel selective anticancer agent, selectively inducing cancer cell death in a caspase independent pathway

First-in-class potent, selective, reversible, and tight binding inhibitor of human monoamine oxidase B (hMAO-B) (hMAO-B IC 50 = 1.52 ± 0.15 nM)

Novel potent DENV2-NS2B/NS3pro inhibitor