Novel non-MPEP site metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs)

Selective modulator of G protein-coupled inward rectifier K (GIRK)

Allosteric modulator of the M1 muscarinic receptor

Novel Positive Allosteric Modulator (PAM) of the Metabotropic Glutamate Receptor 5 (mGlu5)

Novel Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5, Revealing Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity

Potent and specific PAM for the rat mGluR5 receptor

Potent noncompetitive antagonist of Metabotropic_glutamate_receptor_5>metabotropic glutamate receptor 5 (mGlu5)

VU0366248 is a mGlu5 negative allosteric modulator.

Novel Positive Allosteric Modulator (PAM) of the Metabotropic Glutamate Receptor 5 (mGlu5)

Highly potent non-MPEP site metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM)

Muscarinic antagonist; inhibiting ACh-induced Ca(2+) responses at rat M(1-5) receptor subtypes

Novel positive allosteric modulator (PAM) of mGlu4

Allosteric modulator of the M2/5 muscarinic acetylcholine receptor

Highly M1-selective antagonist

Novel M4 muscarinic acetylcholine receptor modulator

Novel mGlu4 positive allosteric modulator (PAM)

Novel negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety

Highly selective muscarinic M1 PAM

Selective orthosteric M1 antagonist

Novel, CNS Penetrant Glucagon-Like Peptide 1 Receptor (GLP-1R) Positive Allosteric Modulator (PAM)

Novel potent and selective metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM)

Potent and selective mGlu5 negative allosteric modulator (NAM)