Novel Nef Protein Inhibitor; Anti-HIV

Novel TNF-α inhibitor

Novel effective immune checkpoint inhibitor (ICI) against the suppression of T-cell activation, proliferation, and tumor cell eradication.

Novel potent small molecule lligand of miR-21, binding to the major groove of miR-21 hairpin conformation

Novel TNF-α inhibitor

Potent and selective agonist of peroxisome proliferator activated receptors-α (PPAR-α)

Potent and selective agonist of peroxisome proliferator activated receptors-α (PPAR-α)

Novel SIRT1 inhibitor

Novel SIRT1 inhibitor

Novel SIRT1 inhibitor

Novel effective immune check point inhibitor (ICI) against the suppression of T-cell activation, proliferation, and tumor cell eradication.

Potent Ebolavirus (EBOV) Inhibitor

Novel dose-dependent inhibitor of TNF-α-induced NF-κB activation

Novel CDK6 inhibitor

Potent and selective agonist of peroxisome proliferator activated receptors-α (PPAR-α)

Novel EGFR triple mutant T790M/C797S allosteric inhibitor

Novel GDNF Family Receptor Agonist

Potent Ebolavirus (EBOV) Inhibitor

Novel Nef Protein Inhibitor; Anti-HIV

Novel blocker of AKT1-FAK interaction, reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation

Novel Zika virus RNA polymerase inhibitor

Novel CtpF inhibitor, inhibiting Ca -dependent ATPase activity in Mtb membrane vesicles