Cat. No. | Product name | CAS No. |
DC44663 |
endo-BCN-PEG2-NH2
endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1263166-93-3 |
DC44664 |
THP-PEG1-alcohol
THP-PEG1-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2162-31-4 |
DC44665 |
Methyl-PEG2-alcohol
Methyl-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
111-77-3 |
DC44666 |
Cl-PEG2-acid
Cl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
170304-76-4 |
DC44667 |
THP-CH3-ethyl propionate
THP-CH3-ethyl propionate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
3539-40-0 |
DC44668 |
Thiol-C10-amide-PEG8
Thiol-C10-amide-PEG8 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1353948-95-4 |
DC44669 |
Thiol-C9-PEG5
Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
130727-42-3 |
DC44670 |
Thiol-C9-PEG4
Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
130727-41-2 |
DC44671 |
5-[Boc(methyl)amino]pentanal
5-[Boc(methyl)amino]pentanal is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
1620280-47-8 |
DC44672 |
Azido-PEG3-aldehyde
Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1807530-10-4 |
DC44673 |
Thiol-C9-PEG7
Thiol-C9-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
130727-44-5 |
DC44674 |
CH2COOH-PEG9-CH2COOH
CH2COOH-PEG9-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2250056-46-1 |
DC44675 |
Bis-PEG2-Boc
Bis-PEG2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
1611468-28-0 |
DC44676 |
Biotin-PEG3-propargyl
Biotin-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1421701-68-9 |
DC44677 |
F-PEG2-COOH
F-PEG2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2383964-72-3 |
DC44678 |
Boc-NH-PPG2
Boc-NH-PPG2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
1312905-31-9 |
DC44679 |
HO-PEG5-CH2COOH
HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
52026-48-9 |
DC44680 |
Propargyl-PEG2-urea-C3-triethoxysilane
Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1637329-79-3 |
DC44681 |
Boc-NHCH2CH2-PEG1-azide
Boc-NHCH2CH2-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
176220-30-7 |
DC44682 |
Biotin-PEG3-SH
Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1244028-52-1 |
DC44683 |
Fmoc-N-amido-PEG3-azide
Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1172605-58-1 |
DC44684 |
Benzyl-PEG3-MS
Benzyl-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
702701-70-0 |
DC44685 |
MS-PEG3-THP
MS-PEG3-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
357204-84-3 |
DC44686 |
Benzyl-PEG7-THP
Benzyl-PEG7-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
230620-75-4 |
DC44687 |
Benzyl-PEG6-THP
Benzyl-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
230620-73-2 |
DC44688 |
Bis-CH2-PEG2-acid
Bis-CH2-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2250056-38-1 |
DC44689 |
Amino-PEG7-t-butyl ester
Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2428400-07-9 |
DC44690 |
Thiol-PEG2-t-butyl ester
Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1398044-50-2 |
DC44691 |
Methyl-PEG4-acyl chloride
Methyl-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
62124-69-0 |
DC44692 |
Azido-PEG9-S-methyl ethanethioate
Azido-PEG9-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2148986-33-6 |
DC44693 |
Azido-PEG5-S-methyl ethanethioate
Azido-PEG5-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1352221-64-7 |
DC44694 |
Methyl-PEG3-Ald
Methyl-PEG3-Ald is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
141981-62-6 |
DC44695 |
Propargyl-PEG9-acid
Propargyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1613752-50-3 |
DC44696 |
Thiol-C9-PEG4-acid
Thiol-C9-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
716339-41-2 |
DC44697 |
Nonylbenzene-PEG8-OH
Nonylbenzene-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
41506-14-3 |
DC44698 |
Bromo-PEG7-azide
Bromo-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1056969-61-9 |
DC44699 |
t-Butyl acetate-PEG2-CH2COOH
t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
883564-93-0 |
DC44700 |
Cyclohexane-PEG1-Br
Cyclohexane-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
131665-94-6 |
DC44701 |
BocNH-PEG5-CH2CH2Br
BocNH-PEG5-CH2CH2Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1392499-33-0 |
DC44702 |
Tos-PEG3-CH2COOtBu
Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1530778-24-5 |
DC53120 |
XD2-149
Featured
XD2-149 is a napabucasin PROTAC as an effective degrader of the E3 ligase ZFP91 with IC50 of 1 μM and 0.8 μM in pancreatic cancer cell lines, MIA PaCa-2 and BxPC-3, respectively. XD2-149 also reduces the expression of STAT3, pSTAT3, and NQO1 proteins. |
|
DC44798 |
ARV-110
Featured
ARV-110 is an orally active, specific androgen receptor (AR) PROTAC degrader. ARV-110 promotes ubiquitination and degradation of AR. ARV-110 can be used for the research of prostate cancer. |
2222112-77-6 |
DC44854 |
β-Naphthoflavone-CH2-Br
β-Naphthoflavone-CH2-Br (β-NF-CH2-Br) is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br can be used to synthesize the PROTAC β-NF-JQ1. |
1282513-77-2 |
DC44855 |
Thalidomide-O-C2-acid
Thalidomide-O-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2369068-42-6 |
DC44856 |
Thalidomide-O-C3-acid
Thalidomide-O-C3-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2169266-64-0 |
DC44857 |
Thalidomide-PEG2-NH2
Thalidomide-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
1957235-94-7 |
DC44858 |
Thalidomide-O-C4-COOH
Thalidomide-O-C4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2169266-67-3 |
DC44859 |
Thalidomide-O-C7-NH2
Thalidomide-O-C7-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2093536-11-7 |
DC44860 |
Thalidomide-O-C5-acid
Thalidomide-O-C5-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2087490-48-8 |
DC44861 |
Thalidomide-O-C8-NH2
Thalidomide-O-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
1957235-91-4 |
DC44862 |
Thalidomide-O-C6-COOH
Thalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2169266-69-5 |
DC44863 |
Thalidomide-PEG3-NH2
Thalidomide-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
1957236-10-0 |
DC44864 |
Thalidomide-O-C7-acid
Thalidomide-O-C7-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2169266-70-8 |
DC44865 |
Thalidomide-Piperazine-Piperidine
Thalidomide-Piperazine-Piperidine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2229716-11-2 |
DC44866 |
Thalidomide-Piperazine-PEG1-NH2
Thalidomide-Piperazine-PEG1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2357111-29-4 |
DC44867 |
Thalidomide-O-C10-NH2
Thalidomide-O-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
1957236-08-6 |
DC44868 |
Thalidomide-NH-PEG2-COOH
Thalidomide-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2412056-45-0 |
DC44869 |
Thalidomide-Piperazine-PEG2-NH2
Thalidomide-Piperazine-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2357110-14-4 |
DC44870 |
Thalidomide-NH-PEG3-COOH
Thalidomide-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2375283-62-6 |
DC44871 |
Thalidomide-PEG4-Propargyl
Thalidomide-PEG4-Propargyl is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2098799-77-8 |
DC44872 |
Thalidomide-PEG5-NH2
Thalidomide-PEG5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2460263-40-3 |
DC44873 |
Thalidomide-Piperazine-PEG3-NH2
Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2357113-68-7 |
DC44874 |
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2435572-48-6 |
DC44875 |
Thalidomide-Propargyne-PEG1-COOH
Thalidomide-Propargyne-PEG1-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44876 |
Thalidomide-5-PEG3-NH2
Thalidomide-5-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44877 |
Glutarimide-Isoindolinone-NH-PEG2-COOH
Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology. |
|
DC44878 |
Thalidomide-Propargyne-PEG2-COOH
Thalidomide-Propargyne-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44879 |
Thalidomide-PEG3-COOH
Thalidomide-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44880 |
Thalidomide-5-PEG4-NH2
Thalidomide-5-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44881 |
Thalidomide-Piperazine-PEG1-COOH
Thalidomide-Piperazine-PEG1-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44882 |
Glutarimide-Isoindolinone-NH-PEG3-COOH
Glutarimide-Isoindolinone-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology. |
|
DC44883 |
Thalidomide-Propargyne-PEG3-COOH
Thalidomide-Propargyne-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44884 |
Thalidomide-PEG4-COOH
Thalidomide-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44885 |
Thalidomide-Piperazine-PEG2-COOH
Thalidomide-Piperazine-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44886 |
Glutarimide-Isoindolinone-NH-PEG4-COOH
Glutarimide-Isoindolinone-NH-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology. |
|
DC44887 |
Thalidomide-PEG5-COOH
Thalidomide-PEG5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44888 |
Thalidomide-Piperazine-PEG3-COOH
Thalidomide-Piperazine-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC44889 |
Pomalidomide 4'-PEG3-azide
Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1 degrader based on Rucaparib by using the PROTAC approach. |
2271036-46-3 |
DC44905 |
Vepdegestrant (ARV-471)
Featured
ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer. |
2229711-68-4 |
DC45199 |
PROTAC BRD4 Degrader-10
PROTAC BRD4 Degrader-10 (compound 8b) is a potent BRD4 degrader. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively. |
2417370-49-9 |
DC45200 |
PROTAC BRD4 Degrader-12
PROTAC BRD4 Degrader-12 (compound 9c) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively. |
2417370-90-0 |
DC45201 |
PROTAC BRD4 Degrader-13
Featured
PROTAC BRD4 Degrader-13 (compound 9d) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-13 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.025 nM and 6.0 nM, respectively. |
2417370-71-7 |
DC45202 |
PROTAC BRD4 Degrader-11
PROTAC BRD4 Degrader-11 (compound 9a) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-11 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.23 nM and 0.38 nM, respectively. |
|
DC45203 |
PROTAC BRD4 Degrader-14
PROTAC BRD4 Degrader-14 is a potent BRD4 degrader, with IC50s of 1.8 nM and 1.7 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-14 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells. |
|
DC45204 |
PROTAC BRD4 Degrader-8
PROTAC BRD4 Degrader-8 is a potent BRD4 inhibitor, with IC50s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells. |
|
DC45205 |
PROTAC BRD4 Degrader-9
PROTAC BRD4 Degrader-9 (compound 8a) is a potent BRD4 degrader. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively. |
2417370-42-2 |
DC45206 |
Bis-sulfone-PEG4-DBCO
Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1854034-70-0 |
DC45207 |
Azido-PEG2-propargyl
Azido-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1245006-63-6 |
DC45208 |
Propargyl-PEG2-NHS ester
Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2512228-06-5 |
DC45209 |
m-PEG5-Propyne
m-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1101668-41-0 |
DC45210 |
S-acetyl-PEG4-amine
S-acetyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1404111-71-2 |
DC45211 |
S-acetyl-PEG5-alcohol
S-acetyl-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1000415-61-1 |
DC45212 |
Propargyl-PEG5-Br
Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1287660-83-6 |
DC45213 |
Mal-amido-PEG3-acid
Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2055353-75-6 |
DC45214 |
S-acetyl-PEG4-NHBoc
S-acetyl-PEG4-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1404111-70-1 |
DC45215 |
Pyrene azide 3
Pyrene azide 3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2252168-06-0 |
DC45216 |
Mal-amido-PEG3-NHS ester
Mal-amido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2055353-77-8 |
DC45217 |
(E)-TCO-PEG4-NHS ester
(E)-TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1621096-79-4 |
DC45218 |
Azido-PEG12-propargyl
Azido-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2264091-72-5 |
DC45219 |
Azido-PEG12-alcohol
Azido-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1111239-69-0 |
DC45220 |
Benzyl-PEG9-Ots
Benzyl-PEG9-Ots is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
393517-91-4 |
DC45221 |
Mal-amido-PEG9-NHS ester
Mal-amido-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2575631-92-2 |
DC45222 |
Biotin-PEG3-Bis-sulfone
Biotin-PEG3-Bis-sulfone is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2055048-58-1 |
DC45223 |
PC DBCO-PEG4-NHS ester
PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2055025-02-8 |
DC45224 |
Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride
Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. |
174422-72-1 |
DC45225 |
Azido-PEG4-azide
Azido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
182760-73-2 |
DC45226 |
Benzyl-PEG4-Azido
Benzyl-PEG4-Azido is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
86770-71-0 |
DC45227 |
Benzyl-PEG4-Ots
Benzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
89346-82-7 |
DC45228 |
m-PEG9-azide
m-PEG9-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
1354521-95-1 |
DC45229 |
Azido-PEG8-azide
Azido-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
361543-07-9 |
DC45230 |
Benzyl-PEG5-Ots
Benzyl-PEG5-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
129086-10-8 |
DC45231 |
Benzyl-PEG6-Ots
Benzyl-PEG6-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
129086-11-9 |
DC45232 |
Azido-PEG8-NHBoc
Azido-PEG8-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
2231845-12-6 |
DC45233 |
Benzyl-PEG7-Ots
Benzyl-PEG7-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|
DC45234 |
Benzyl-PEG8-Ots
Benzyl-PEG8-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
1144113-17-6 |
DC45235 |
m-PEG13-azide
m-PEG13-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45236 |
DBCO-PEG13-NHS ester
DBCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45237 |
S-acetyl-PEG4-Thiol
S-acetyl-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45238 |
Propargyl-PEG7-amine
Propargyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45239 |
m-PEG5-amino-Mal
m-PEG5-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45240 |
Propargyl-PEG7-Br
Propargyl-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45241 |
Mal-amido-PEG5-acid
Mal-amido-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45242 |
Azido-PEG7-NHS ester
Azido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45243 |
Propargyl-PEG11-amine
Propargyl-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45244 |
Propargyl-PEG11-acid
Propargyl-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45245 |
Mal-PEG10-acid
Mal-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45246 |
Propargyl-PEG12-acid
Propargyl-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45247 |
Propargyl-PEG13-OH
Propargyl-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45248 |
Mal-amido-PEG7-NHS ester
Mal-amido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45249 |
Mal-PEG10-Boc
Mal-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45250 |
Mal-PEG10-NHS ester
Mal-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45251 |
Propargyl-PEG13-Boc
Propargyl-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45252 |
m-PEG14-NHS ester
m-PEG14-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45253 |
Fmoc-PEG9-NHS ester
Fmoc-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45254 |
Fmoc-PEG10-NHS ester
Fmoc-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45255 |
Bis-sulfone-PEG4-Tetrazine
Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45256 |
Azido-PEG10-propargyl
Azido-PEG10-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45257 |
Benzyl-PEG10-Ots
Benzyl-PEG10-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|
DC45258 |
Benzyl-PEG12-Ots
Benzyl-PEG12-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|
DC55003 |
XY028-140 (MS140)
Featured
XY028-140 (MS-140) is a potent and selective PROTAC-based CDK4/CDK6 kinase degrader. XY028-140 specifically inhibits RB-E2F signaling and reduces CDK4 and CDK6 protein levels in a dose- and time-dependent manner in vitro. In addition, XY028-140 can degrade its targets by linking them with ubiquitin-proteasome mechanism. Further, the degradation of CDK4/6 protein by XY028-140 is specifically mediated by CRBN. Therefore, XY028-140 effectively and selectively inhibits and degrades CDK4/6 kinase by targeting CDK4/6 kinase in CDK4/6i-S (CDK4/6 inhibitor-sensitive) tumor cells to the CRL4-CRBN-E3 ubiquitin complex. Compared with CDK6 wild-type cells, XY028-140 treatment of cells expressing wild-type or mutation-activated CDK6 resulted in a more effective degradation of CDK6 (S178P). |
2229974-83-6 |
DC45311 |
Thalidomide-O-C6-NH2
Thalidomide-O-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
1957235-98-1 |
DC45314 |
Thalidomide-O-amido-C8-NH2 hydrochloride
Thalidomide-O-amido-C8-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs. |
2415263-07-7 |
DC45696 |
Lenalidomide-6-F
Lenalidomide-6-F is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-6-F can be connected to the ligand for protein by a linker to form PROTAC. |
2468780-87-0 |
DC45697 |
Lenalidomide-4-aminomethyl
Lenalidomide-4-aminomethyl is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl can be connected to the ligand for protein by a linker to form PROTAC. |
790652-68-5 |
DC45698 |
Lenalidomide-4-aminomethyl hydrochloride
Lenalidomide-4-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC |
444289-05-8 |
DC45699 |
Lenalidomide-5-Br
Lenalidomide-5-Br is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-Br can be connected to the ligand for protein by a linker to form PROTAC. |
1010100-26-1 |
DC45700 |
Lenalidomide-5-aminomethyl
Lenalidomide-5-aminomethyl is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-aminomethyl can be connected to the ligand for protein by a linker to form PROTAC. |
1010100-28-3 |
DC45701 |
Pomalidomide-PEG3-C2-NH2 hydrochloride
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2446474-09-3 |
DC45702 |
Thalidomide-NH-C6-NH2 hydrochloride
Thalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2375194-37-7 |
DC45703 |
(S,R,S)-AHPC-C3-NH2 hydrochloride
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. |
|
DC45704 |
Thalidomide-O-C4-NH2
Thalidomide-O-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
1957235-96-9 |
DC45705 |
Thalidomide-NH-PEG1-NH2 hydrochloride
Thalidomide-NH-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2154342-56-8 |
DC45706 |
Pomalidomide-C3-NH2 hydrochloride
Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2154342-45-5 |
DC45707 |
Pomalidomide-C3-NH2
Pomalidomide-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2093388-20-4 |
DC45708 |
Pomalidomide 4'-PEG2-azide
Pomalidomide 4'-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2271036-45-2 |
DC45709 |
Thalidomide-O-C8-NH2 hydrochloride
Thalidomide-O-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2636798-38-2 |
DC45710 |
Pomalidomide-amino-PEG5-NH2 hydrochloride
Featured
Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2421217-05-0 |
DC45711 |
Pomalidomide-amino-PEG5-NH2
Pomalidomide-amino-PEG5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2421217-04-9 |
DC45712 |
Pomalidomide-amino-PEG3-NH2 hydrochloride
Featured
Pomalidomide-amino-PEG3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2380273-75-4 |
DC45713 |
Pomalidomide-amino-PEG3-NH2
Pomalidomide-amino-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2380273-74-3 |
DC45714 |
Thalidomide-piperazine-Boc
Thalidomide-piperazine-Boc is an intermediate that can be used in the synthesis of B-cell lymphoma 6 protein (BCL6) PROTAC. |
2222114-64-7 |
DC45715 |
Thalidomide-NH-amido-C4-NH2
Thalidomide-NH-amido-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2093388-67-9 |
DC45716 |
Thalidomide-NH-amido-C4-NH2 hydrochloride
Thalidomide-NH-amido-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45717 |
Thalidomide-NH-C5-NH2
Thalidomide-NH-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2093386-39-9 |
DC45718 |
Thalidomide 4'-ether-alkylC2-amine
Thalidomide 4'-ether-alkylC2-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
390367-50-7 |
DC45719 |
(S,R,S)-AHPC-C2-NH2
(S,R,S)-AHPC-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. |
2241643-69-4 |
DC45720 |
Pomalidomide-C4-NH2
Pomalidomide-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
1957236-34-8 |
DC45721 |
Pomalidomide-C4-NH2 hydrochloride
Pomalidomide-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2162120-73-0 |
DC45722 |
Thalidomide-NH-C8-NH2
Thalidomide-NH-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
1957236-36-0 |
DC45723 |
Thalidomide-NH-C8-NH2 hydrochloride
Thalidomide-NH-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2446474-06-0 |
DC45724 |
Thalidomide-O-C3-NH2
Thalidomide-O-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2509360-22-7 |
DC45725 |
Thalidomide-O-C3-NH2 hydrochloride
Thalidomide-O-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45726 |
Thalidomide-O-C5-NH2
Thalidomide-O-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2307477-23-0 |
DC45727 |
Thalidomide-O-C5-NH2 hydrochloride
Thalidomide-O-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2419145-66-5 |
DC45728 |
Thalidomide-NH-amido-C2-NH2
Thalidomide-NH-amido-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45729 |
Thalidomide-NH-amido-C2-NH2 hydrochloride
Thalidomide-NH-amido-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45730 |
Thalidomide-NH-amido-C3-NH2
Thalidomide-NH-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45731 |
Thalidomide-NH-amido-C3-NH2 hydrochloride
Thalidomide-NH-amido-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45732 |
Thalidomide-NH-amido-C5-NH2
Thalidomide-NH-amido-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45733 |
Thalidomide-NH-amido-C5-NH2 hydrochloride
Thalidomide-NH-amido-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45734 |
Thalidomide-NH-amido-C6-NH2
Thalidomide-NH-amido-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45735 |
Thalidomide-NH-amido-C6-NH2 hydrochloride
Thalidomide-NH-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45736 |
Thalidomide-NH-amido-C8-NH2
Thalidomide-NH-amido-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45737 |
Thalidomide-NH-amido-C8-NH2 hydrochloride
Thalidomide-NH-amido-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45738 |
Thalidomide-NH-amido-PEG1-C2-NH2
Thalidomide-NH-amido-PEG1-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45739 |
Thalidomide-NH-amido-PEG1-C2-NH2 hydrochloride
Thalidomide-NH-amido-PEG1-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45740 |
Thalidomide-NH-amido-PEG2-C2-NH2
Thalidomide-NH-amido-PEG2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45741 |
Thalidomide-NH-amido-PEG2-C2-NH2 hydrochloride
Thalidomide-NH-amido-PEG2-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45742 |
Thalidomide-NH-amido-PEG3-C2-NH2
Thalidomide-NH-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45743 |
Thalidomide-NH-amido-PEG3-C2-NH2 hydrochloride
Thalidomide-NH-amido-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45744 |
Thalidomide-NH-amido-PEG4-C2-NH2
Thalidomide-NH-amido-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45745 |
Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride
Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45746 |
Thalidomide-amido-PEG2-NH2
Thalidomide-amido-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2380273-72-1 |
DC45747 |
Thalidomide-amido-PEG2-NH2 hydrochloride
Thalidomide-amido-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
2380273-73-2 |
DC45748 |
Pomalidomide-amino-PEG4-NH2
Pomalidomide-amino-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2331259-44-8 |
DC45749 |
Pomalidomide-amino-PEG4-NH2 hydrochloride
Pomalidomide-amino-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. |
2331259-45-9 |
DC45750 |
Thalidomide-O-C11-acid
Thalidomide-O-C11-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
|
DC45751 |
(S,R,S)-AHPC-C1-NH2
(S,R,S)-AHPC-C1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology. |
2010986-20-4 |
DC45752 |
(S,R,S)-AHPC-C1-NH2 hydrochloride
(S,R,S)-AHPC-C1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology. |
2361120-26-3 |
DC45753 |
Thalidomide-O-amide-C5-NH2 TFA
Thalidomide-O-amide-C5-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |