Home > PROTACs
Cat. No. Product name CAS No.
DC44663 endo-BCN-PEG2-NH2

endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1263166-93-3
DC44664 THP-PEG1-alcohol

THP-PEG1-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2162-31-4
DC44665 Methyl-PEG2-alcohol

Methyl-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

111-77-3
DC44666 Cl-PEG2-acid

Cl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

170304-76-4
DC44667 THP-CH3-ethyl propionate

THP-CH3-ethyl propionate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

3539-40-0
DC44668 Thiol-C10-amide-PEG8

Thiol-C10-amide-PEG8 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1353948-95-4
DC44669 Thiol-C9-PEG5

Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

130727-42-3
DC44670 Thiol-C9-PEG4

Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

130727-41-2
DC44671 5-[Boc(methyl)amino]pentanal

5-[Boc(methyl)amino]pentanal is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

1620280-47-8
DC44672 Azido-PEG3-aldehyde

Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1807530-10-4
DC44673 Thiol-C9-PEG7

Thiol-C9-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

130727-44-5
DC44674 CH2COOH-PEG9-CH2COOH

CH2COOH-PEG9-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2250056-46-1
DC44675 Bis-PEG2-Boc

Bis-PEG2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

1611468-28-0
DC44676 Biotin-PEG3-propargyl

Biotin-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1421701-68-9
DC44677 F-PEG2-COOH

F-PEG2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2383964-72-3
DC44678 Boc-NH-PPG2

Boc-NH-PPG2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

1312905-31-9
DC44679 HO-PEG5-CH2COOH

HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

52026-48-9
DC44680 Propargyl-PEG2-urea-C3-triethoxysilane

Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1637329-79-3
DC44681 Boc-NHCH2CH2-PEG1-azide

Boc-NHCH2CH2-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

176220-30-7
DC44682 Biotin-PEG3-SH

Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1244028-52-1
DC44683 Fmoc-N-amido-PEG3-azide

Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1172605-58-1
DC44684 Benzyl-PEG3-MS

Benzyl-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

702701-70-0
DC44685 MS-PEG3-THP

MS-PEG3-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

357204-84-3
DC44686 Benzyl-PEG7-THP

Benzyl-PEG7-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

230620-75-4
DC44687 Benzyl-PEG6-THP

Benzyl-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

230620-73-2
DC44688 Bis-CH2-PEG2-acid

Bis-CH2-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2250056-38-1
DC44689 Amino-PEG7-t-butyl ester

Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2428400-07-9
DC44690 Thiol-PEG2-t-butyl ester

Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1398044-50-2
DC44691 Methyl-PEG4-acyl chloride

Methyl-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

62124-69-0
DC44692 Azido-PEG9-S-methyl ethanethioate

Azido-PEG9-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2148986-33-6
DC44693 Azido-PEG5-S-methyl ethanethioate

Azido-PEG5-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1352221-64-7
DC44694 Methyl-PEG3-Ald

Methyl-PEG3-Ald is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

141981-62-6
DC44695 Propargyl-PEG9-acid

Propargyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1613752-50-3
DC44696 Thiol-C9-PEG4-acid

Thiol-C9-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

716339-41-2
DC44697 Nonylbenzene-PEG8-OH

Nonylbenzene-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

41506-14-3
DC44698 Bromo-PEG7-azide

Bromo-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1056969-61-9
DC44699 t-Butyl acetate-PEG2-CH2COOH

t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

883564-93-0
DC44700 Cyclohexane-PEG1-Br

Cyclohexane-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

131665-94-6
DC44701 BocNH-PEG5-CH2CH2Br

BocNH-PEG5-CH2CH2Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1392499-33-0
DC44702 Tos-PEG3-CH2COOtBu

Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1530778-24-5
DC53120 XD2-149 Featured

XD2-149 is a napabucasin PROTAC as an effective degrader of the E3 ligase ZFP91 with IC50 of 1 μM and 0.8 μM in pancreatic cancer cell lines, MIA PaCa-2 and BxPC-3, respectively. XD2-149 also reduces the expression of STAT3, pSTAT3, and NQO1 proteins.

DC44798 ARV-110 Featured

ARV-110 is an orally active, specific androgen receptor (AR) PROTAC degrader. ARV-110 promotes ubiquitination and degradation of AR. ARV-110 can be used for the research of prostate cancer.

2222112-77-6
DC44854 β-Naphthoflavone-CH2-Br

β-Naphthoflavone-CH2-Br (β-NF-CH2-Br) is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br can be used to synthesize the PROTAC β-NF-JQ1.

1282513-77-2
DC44855 Thalidomide-O-C2-acid

Thalidomide-O-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2369068-42-6
DC44856 Thalidomide-O-C3-acid

Thalidomide-O-C3-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2169266-64-0
DC44857 Thalidomide-PEG2-NH2

Thalidomide-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

1957235-94-7
DC44858 Thalidomide-O-C4-COOH

Thalidomide-O-C4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2169266-67-3
DC44859 Thalidomide-O-C7-NH2

Thalidomide-O-C7-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2093536-11-7
DC44860 Thalidomide-O-C5-acid

Thalidomide-O-C5-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2087490-48-8
DC44861 Thalidomide-O-C8-NH2

Thalidomide-O-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

1957235-91-4
DC44862 Thalidomide-O-C6-COOH

Thalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2169266-69-5
DC44863 Thalidomide-PEG3-NH2

Thalidomide-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

1957236-10-0
DC44864 Thalidomide-O-C7-acid

Thalidomide-O-C7-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2169266-70-8
DC44865 Thalidomide-Piperazine-Piperidine

Thalidomide-Piperazine-Piperidine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2229716-11-2
DC44866 Thalidomide-Piperazine-PEG1-NH2

Thalidomide-Piperazine-PEG1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2357111-29-4
DC44867 Thalidomide-O-C10-NH2

Thalidomide-O-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

1957236-08-6
DC44868 Thalidomide-NH-PEG2-COOH

Thalidomide-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2412056-45-0
DC44869 Thalidomide-Piperazine-PEG2-NH2

Thalidomide-Piperazine-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2357110-14-4
DC44870 Thalidomide-NH-PEG3-COOH

Thalidomide-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2375283-62-6
DC44871 Thalidomide-PEG4-Propargyl

Thalidomide-PEG4-Propargyl is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2098799-77-8
DC44872 Thalidomide-PEG5-NH2

Thalidomide-PEG5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2460263-40-3
DC44873 Thalidomide-Piperazine-PEG3-NH2

Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2357113-68-7
DC44874 Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2435572-48-6
DC44875 Thalidomide-Propargyne-PEG1-COOH

Thalidomide-Propargyne-PEG1-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44876 Thalidomide-5-PEG3-NH2

Thalidomide-5-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44877 Glutarimide-Isoindolinone-NH-PEG2-COOH

Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology.

DC44878 Thalidomide-Propargyne-PEG2-COOH

Thalidomide-Propargyne-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44879 Thalidomide-PEG3-COOH

Thalidomide-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44880 Thalidomide-5-PEG4-NH2

Thalidomide-5-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44881 Thalidomide-Piperazine-PEG1-COOH

Thalidomide-Piperazine-PEG1-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44882 Glutarimide-Isoindolinone-NH-PEG3-COOH

Glutarimide-Isoindolinone-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology.

DC44883 Thalidomide-Propargyne-PEG3-COOH

Thalidomide-Propargyne-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44884 Thalidomide-PEG4-COOH

Thalidomide-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44885 Thalidomide-Piperazine-PEG2-COOH

Thalidomide-Piperazine-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44886 Glutarimide-Isoindolinone-NH-PEG4-COOH

Glutarimide-Isoindolinone-NH-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology.

DC44887 Thalidomide-PEG5-COOH

Thalidomide-PEG5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44888 Thalidomide-Piperazine-PEG3-COOH

Thalidomide-Piperazine-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC44889 Pomalidomide 4'-PEG3-azide

Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1 degrader based on Rucaparib by using the PROTAC approach.

2271036-46-3
DC44905 Vepdegestrant (ARV-471) Featured

ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer.

2229711-68-4
DC45199 PROTAC BRD4 Degrader-10

PROTAC BRD4 Degrader-10 (compound 8b) is a potent BRD4 degrader. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively.

2417370-49-9
DC45200 PROTAC BRD4 Degrader-12

PROTAC BRD4 Degrader-12 (compound 9c) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively.

2417370-90-0
DC45201 PROTAC BRD4 Degrader-13 Featured

PROTAC BRD4 Degrader-13 (compound 9d) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-13 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.025 nM and 6.0 nM, respectively.

2417370-71-7
DC45202 PROTAC BRD4 Degrader-11

PROTAC BRD4 Degrader-11 (compound 9a) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-11 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.23 nM and 0.38 nM, respectively.

DC45203 PROTAC BRD4 Degrader-14

PROTAC BRD4 Degrader-14 is a potent BRD4 degrader, with IC50s of 1.8 nM and 1.7 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-14 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells.

DC45204 PROTAC BRD4 Degrader-8

PROTAC BRD4 Degrader-8 is a potent BRD4 inhibitor, with IC50s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells.

DC45205 PROTAC BRD4 Degrader-9

PROTAC BRD4 Degrader-9 (compound 8a) is a potent BRD4 degrader. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively.

2417370-42-2
DC45206 Bis-sulfone-PEG4-DBCO

Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1854034-70-0
DC45207 Azido-PEG2-propargyl

Azido-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1245006-63-6
DC45208 Propargyl-PEG2-NHS ester

Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2512228-06-5
DC45209 m-PEG5-Propyne

m-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1101668-41-0
DC45210 S-acetyl-PEG4-amine

S-acetyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1404111-71-2
DC45211 S-acetyl-PEG5-alcohol

S-acetyl-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1000415-61-1
DC45212 Propargyl-PEG5-Br

Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1287660-83-6
DC45213 Mal-amido-PEG3-acid

Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2055353-75-6
DC45214 S-acetyl-PEG4-NHBoc

S-acetyl-PEG4-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1404111-70-1
DC45215 Pyrene azide 3

Pyrene azide 3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2252168-06-0
DC45216 Mal-amido-PEG3-NHS ester

Mal-amido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2055353-77-8
DC45217 (E)-TCO-PEG4-NHS ester

(E)-TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1621096-79-4
DC45218 Azido-PEG12-propargyl

Azido-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2264091-72-5
DC45219 Azido-PEG12-alcohol

Azido-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1111239-69-0
DC45220 Benzyl-PEG9-Ots

Benzyl-PEG9-Ots is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

393517-91-4
DC45221 Mal-amido-PEG9-NHS ester

Mal-amido-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2575631-92-2
DC45222 Biotin-PEG3-Bis-sulfone

Biotin-PEG3-Bis-sulfone is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2055048-58-1
DC45223 PC DBCO-PEG4-NHS ester

PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2055025-02-8
DC45224 Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride

Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

174422-72-1
DC45225 Azido-PEG4-azide

Azido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

182760-73-2
DC45226 Benzyl-PEG4-Azido

Benzyl-PEG4-Azido is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

86770-71-0
DC45227 Benzyl-PEG4-Ots

Benzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

89346-82-7
DC45228 m-PEG9-azide

m-PEG9-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

1354521-95-1
DC45229 Azido-PEG8-azide

Azido-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

361543-07-9
DC45230 Benzyl-PEG5-Ots

Benzyl-PEG5-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

129086-10-8
DC45231 Benzyl-PEG6-Ots

Benzyl-PEG6-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

129086-11-9
DC45232 Azido-PEG8-NHBoc

Azido-PEG8-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

2231845-12-6
DC45233 Benzyl-PEG7-Ots

Benzyl-PEG7-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

DC45234 Benzyl-PEG8-Ots

Benzyl-PEG8-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

1144113-17-6
DC45235 m-PEG13-azide

m-PEG13-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45236 DBCO-PEG13-NHS ester

DBCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45237 S-acetyl-PEG4-Thiol

S-acetyl-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45238 Propargyl-PEG7-amine

Propargyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45239 m-PEG5-amino-Mal

m-PEG5-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45240 Propargyl-PEG7-Br

Propargyl-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45241 Mal-amido-PEG5-acid

Mal-amido-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45242 Azido-PEG7-NHS ester

Azido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45243 Propargyl-PEG11-amine

Propargyl-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45244 Propargyl-PEG11-acid

Propargyl-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45245 Mal-PEG10-acid

Mal-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45246 Propargyl-PEG12-acid

Propargyl-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45247 Propargyl-PEG13-OH

Propargyl-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45248 Mal-amido-PEG7-NHS ester

Mal-amido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45249 Mal-PEG10-Boc

Mal-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45250 Mal-PEG10-NHS ester

Mal-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45251 Propargyl-PEG13-Boc

Propargyl-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45252 m-PEG14-NHS ester

m-PEG14-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45253 Fmoc-PEG9-NHS ester

Fmoc-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45254 Fmoc-PEG10-NHS ester

Fmoc-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45255 Bis-sulfone-PEG4-Tetrazine

Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45256 Azido-PEG10-propargyl

Azido-PEG10-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45257 Benzyl-PEG10-Ots

Benzyl-PEG10-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

DC45258 Benzyl-PEG12-Ots

Benzyl-PEG12-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

DC55003 XY028-140 (MS140) Featured

XY028-140 (MS-140) is a potent and selective PROTAC-based CDK4/CDK6 kinase degrader. XY028-140 specifically inhibits RB-E2F signaling and reduces CDK4 and CDK6 protein levels in a dose- and time-dependent manner in vitro. In addition, XY028-140 can degrade its targets by linking them with ubiquitin-proteasome mechanism. Further, the degradation of CDK4/6 protein by XY028-140 is specifically mediated by CRBN. Therefore, XY028-140 effectively and selectively inhibits and degrades CDK4/6 kinase by targeting CDK4/6 kinase in CDK4/6i-S (CDK4/6 inhibitor-sensitive) tumor cells to the CRL4-CRBN-E3 ubiquitin complex. Compared with CDK6 wild-type cells, XY028-140 treatment of cells expressing wild-type or mutation-activated CDK6 resulted in a more effective degradation of CDK6 (S178P).

2229974-83-6
DC45311 Thalidomide-O-C6-NH2

Thalidomide-O-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

1957235-98-1
DC45314 Thalidomide-O-amido-C8-NH2 hydrochloride

Thalidomide-O-amido-C8-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.

2415263-07-7
DC45696 Lenalidomide-6-F

Lenalidomide-6-F is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-6-F can be connected to the ligand for protein by a linker to form PROTAC.

2468780-87-0
DC45697 Lenalidomide-4-aminomethyl

Lenalidomide-4-aminomethyl is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl can be connected to the ligand for protein by a linker to form PROTAC.

790652-68-5
DC45698 Lenalidomide-4-aminomethyl hydrochloride

Lenalidomide-4-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC

444289-05-8
DC45699 Lenalidomide-5-Br

Lenalidomide-5-Br is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-Br can be connected to the ligand for protein by a linker to form PROTAC.

1010100-26-1
DC45700 Lenalidomide-5-aminomethyl

Lenalidomide-5-aminomethyl is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-aminomethyl can be connected to the ligand for protein by a linker to form PROTAC.

1010100-28-3
DC45701 Pomalidomide-PEG3-C2-NH2 hydrochloride

Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2446474-09-3
DC45702 Thalidomide-NH-C6-NH2 hydrochloride

Thalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2375194-37-7
DC45703 (S,R,S)-AHPC-C3-NH2 hydrochloride

(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.

DC45704 Thalidomide-O-C4-NH2

Thalidomide-O-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

1957235-96-9
DC45705 Thalidomide-NH-PEG1-NH2 hydrochloride

Thalidomide-NH-PEG1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2154342-56-8
DC45706 Pomalidomide-C3-NH2 hydrochloride

Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2154342-45-5
DC45707 Pomalidomide-C3-NH2

Pomalidomide-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2093388-20-4
DC45708 Pomalidomide 4'-PEG2-azide

Pomalidomide 4'-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2271036-45-2
DC45709 Thalidomide-O-C8-NH2 hydrochloride

Thalidomide-O-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2636798-38-2
DC45710 Pomalidomide-amino-PEG5-NH2 hydrochloride Featured

Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2421217-05-0
DC45711 Pomalidomide-amino-PEG5-NH2

Pomalidomide-amino-PEG5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2421217-04-9
DC45712 Pomalidomide-amino-PEG3-NH2 hydrochloride Featured

Pomalidomide-amino-PEG3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2380273-75-4
DC45713 Pomalidomide-amino-PEG3-NH2

Pomalidomide-amino-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2380273-74-3
DC45714 Thalidomide-piperazine-Boc

Thalidomide-piperazine-Boc is an intermediate that can be used in the synthesis of B-cell lymphoma 6 protein (BCL6) PROTAC.

2222114-64-7
DC45715 Thalidomide-NH-amido-C4-NH2

Thalidomide-NH-amido-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2093388-67-9
DC45716 Thalidomide-NH-amido-C4-NH2 hydrochloride

Thalidomide-NH-amido-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45717 Thalidomide-NH-C5-NH2

Thalidomide-NH-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2093386-39-9
DC45718 Thalidomide 4'-ether-alkylC2-amine

Thalidomide 4'-ether-alkylC2-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

390367-50-7
DC45719 (S,R,S)-AHPC-C2-NH2

(S,R,S)-AHPC-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.

2241643-69-4
DC45720 Pomalidomide-C4-NH2

Pomalidomide-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

1957236-34-8
DC45721 Pomalidomide-C4-NH2 hydrochloride

Pomalidomide-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2162120-73-0
DC45722 Thalidomide-NH-C8-NH2

Thalidomide-NH-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

1957236-36-0
DC45723 Thalidomide-NH-C8-NH2 hydrochloride

Thalidomide-NH-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2446474-06-0
DC45724 Thalidomide-O-C3-NH2

Thalidomide-O-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2509360-22-7
DC45725 Thalidomide-O-C3-NH2 hydrochloride

Thalidomide-O-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45726 Thalidomide-O-C5-NH2

Thalidomide-O-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2307477-23-0
DC45727 Thalidomide-O-C5-NH2 hydrochloride

Thalidomide-O-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2419145-66-5
DC45728 Thalidomide-NH-amido-C2-NH2

Thalidomide-NH-amido-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45729 Thalidomide-NH-amido-C2-NH2 hydrochloride

Thalidomide-NH-amido-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45730 Thalidomide-NH-amido-C3-NH2

Thalidomide-NH-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45731 Thalidomide-NH-amido-C3-NH2 hydrochloride

Thalidomide-NH-amido-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45732 Thalidomide-NH-amido-C5-NH2

Thalidomide-NH-amido-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45733 Thalidomide-NH-amido-C5-NH2 hydrochloride

Thalidomide-NH-amido-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45734 Thalidomide-NH-amido-C6-NH2

Thalidomide-NH-amido-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45735 Thalidomide-NH-amido-C6-NH2 hydrochloride

Thalidomide-NH-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45736 Thalidomide-NH-amido-C8-NH2

Thalidomide-NH-amido-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45737 Thalidomide-NH-amido-C8-NH2 hydrochloride

Thalidomide-NH-amido-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45738 Thalidomide-NH-amido-PEG1-C2-NH2

Thalidomide-NH-amido-PEG1-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45739 Thalidomide-NH-amido-PEG1-C2-NH2 hydrochloride

Thalidomide-NH-amido-PEG1-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45740 Thalidomide-NH-amido-PEG2-C2-NH2

Thalidomide-NH-amido-PEG2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45741 Thalidomide-NH-amido-PEG2-C2-NH2 hydrochloride

Thalidomide-NH-amido-PEG2-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45742 Thalidomide-NH-amido-PEG3-C2-NH2

Thalidomide-NH-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45743 Thalidomide-NH-amido-PEG3-C2-NH2 hydrochloride

Thalidomide-NH-amido-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45744 Thalidomide-NH-amido-PEG4-C2-NH2

Thalidomide-NH-amido-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45745 Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride

Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45746 Thalidomide-amido-PEG2-NH2

Thalidomide-amido-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2380273-72-1
DC45747 Thalidomide-amido-PEG2-NH2 hydrochloride

Thalidomide-amido-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

2380273-73-2
DC45748 Pomalidomide-amino-PEG4-NH2

Pomalidomide-amino-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2331259-44-8
DC45749 Pomalidomide-amino-PEG4-NH2 hydrochloride

Pomalidomide-amino-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

2331259-45-9
DC45750 Thalidomide-O-C11-acid

Thalidomide-O-C11-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

DC45751 (S,R,S)-AHPC-C1-NH2

(S,R,S)-AHPC-C1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology.

2010986-20-4
DC45752 (S,R,S)-AHPC-C1-NH2 hydrochloride

(S,R,S)-AHPC-C1-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology.

2361120-26-3
DC45753 Thalidomide-O-amide-C5-NH2 TFA

Thalidomide-O-amide-C5-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

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