Home > Inhibitors & Agonists > Tyrosine Kinase > TAM Receptor (Tyro3-Axl-Mer)
Cat. No. Product name CAS No.
DC74428 Adrixetinib

Adrixetinib is a small molecule inhibitor of Axl/Mer RTK.

2394874-66-7
DC74429 ER-851

ER851 (ER-851) is a potent and highly selective AXL inhibitor.

DC74430 INCB081776

INCB081776 is a potent and selective dual inhibitor of AXL and MERTK with IC50 of 16 and 14 nM respectively, 30-fold selectivity over TYRO3.

DC74431 R992

R992 (MERTK inhibitor) is a novel potent, selective and orally bioavailable inhibitor of Mer tyrosine kinase (MerTK) with IC50 of 18 nM in ADP-Glo assays.

2171523-99-0
DC74432 UNC2025 hydrochloride

UNC2025 is a potent, orally bioavailable Mer/FLT3 dual inhibitor with IC50 of 0.74/0.8 nM, 700-fold less active against Met compared to Mer.

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