UNC2025 hydrochloride|CAS |DC Chemicals

Cas No.:
Chemical Name:	UNC2025 hydrochloride
Formula:	C₂₈H₄₁ClN₆O
M.Wt:	513.1177

MSDS

Cat. No.	Product name	Field of application
DC44222	DS-1205b free base	DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.
DC11690	RU-302	RU-302 is a small molecule pan-TAM inhibitor that targets the TAM Ig1-Gas6 interface, blocks Gas6-dependent TAM activation.
DC7999	LDC1267	LDC1267 is a highly selective TAM(Tyro3, Axl and Mer) kinase inhibitor with IC50 of <5 nM/8 nM/29 nM for Tyro3,Axl and Mer respectively.
DC10337	CEP-40783	CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively.
DC74432	UNC2025 hydrochloride	UNC2025 is a potent, orally bioavailable Mer/FLT3 dual inhibitor with IC50 of 0.74/0.8 nM, 700-fold less active against Met compared to Mer.
DC74431	R992	R992 (MERTK inhibitor) is a novel potent, selective and orally bioavailable inhibitor of Mer tyrosine kinase (MerTK) with IC50 of 18 nM in ADP-Glo assays.
DC74430	INCB081776	INCB081776 is a potent and selective dual inhibitor of AXL and MERTK with IC50 of 16 and 14 nM respectively, 30-fold selectivity over TYRO3.
DC74429	ER-851	ER851 (ER-851) is a potent and highly selective AXL inhibitor.
DC74428	Adrixetinib	Adrixetinib is a small molecule inhibitor of Axl/Mer RTK.
DC72003	TL4830031	TL4830031 (compound 8i), a quinolone antibiotic derivatives, is a potent Axl inhibitor with an IC50 value of 26 nM. TL4830031 inhibits the phosphorylation of Axl. TL4830031 inhibits cell invasion and migration. TL4830031 can be used for cancer research.