| DC33635 |
DODAP
|
DODAP, also known as 1,2-Dioleoyl-3-dimethylammonium-propane, is a cationic lipid. It has been used as a component in liposomes that can be used to encapsulate siRNA, immunostimulatory oligodeoxynucleotides, antisense oligonucleotides, or chemotherapeutic agents for in vitro and in vivo delivery. |
| DC58047 |
PEG2000-DSPE
|
PEG2000-DSPE is used for creating micelles that are able to carry drugs with low solubility. |
| DC31000 |
LP-01
|
LP-01 is a cationic lipids useful in the delivery of biologically active agents to cells and tissues. |
| DC58066 |
m7G(5')ppp(5')(2'OMeA)pG
|
m7G(5')ppp(5')(2'OMeA)pG is a co-transcription capping reagent for in vitro transcription of 5'capped mRNA to produce Cap 1 structure. Cap AG has been shown in the literature to provide a capping efficiency of up to 98%.
m7G(5')ppp(5')(2'OMeA)pG requires an AG initiator. m7G(5')ppp(5')(2'OMeA)pG typically provides >90% capped material generating a naturally occurring Cap 1 structure. |
| DC80099 |
PF-06885249(PF249)
|
PF-249(PF06885249) is a potent, selective AMPK β1-containing complexes activator; increases the phosphorylation of the AMPK substrate ACC at S79 with EC50 of 296 nM, potently inhibits de novo lipogenesis (IC50=15 nM) in primary rat hepatocytes. |
| DC60335 |
Centanamycin
|
Centanamycin alkylates the A-T-rich minor groove of the DNA and thereby blocks DNA replication. Centanamycin potently inhibits replication of human cytomegalovirus (HCMV), mouse CMV (MCMV), and herpes simplex virus-2 (HSV-2) in vitro. Centanamycin-attenuated whole virion MCMV elicits a robust serum neutralizing antibody response and protects the mice from live-virus challenge. |
| DC82050 |
Coelenterazine H
|
Coelenterazine h is a derivative of Coelenterazine. Coelenterazine h is more sensitive to Ca2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca2+ concentrations. |
| DC60334 |
DRP-104
|
DRP-104 is a 6-Diazo-5-oxo-l-norleucine (DON) peptide prodrug. DRP-104 delivers a prodigious 11-fold greater exposure of DON to tumor versus GI tissues. |
| DC60333 |
BRD7586
|
BRD-7586(BRD 7586) is a cell-permeable small molecule inhibitor of SpCas9 with EC50 of 6.2 µM and 5.7 µM in the eGFP-disruption and HiBiT-knock-in assays, respectively. BRD7586 specifically engages SpCas9 but not Cas12a in cells and enhances SpCas9 specificity at multiple loci. |
| DC82032 |
Methoxy-X04
|
Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques. |
