DC70000 |
Lysyllysyllysine
|
Lysyllysyllysine is a cationic moietie that may be used in the construction of gene delivery vectors and DNA nanoparticles. |
DC33635 |
DODAP
|
DODAP, also known as 1,2-Dioleoyl-3-dimethylammonium-propane, is a cationic lipid. It has been used as a component in liposomes that can be used to encapsulate siRNA, immunostimulatory oligodeoxynucleotides, antisense oligonucleotides, or chemotherapeutic agents for in vitro and in vivo delivery. |
DC58047 |
PEG2000-DSPE
|
PEG2000-DSPE is used for creating micelles that are able to carry drugs with low solubility. |
DC31000 |
LP-01
|
LP-01 is a cationic lipids useful in the delivery of biologically active agents to cells and tissues. |
DC58066 |
m7G(5')ppp(5')(2'OMeA)pG
|
m7G(5')ppp(5')(2'OMeA)pG is a co-transcription capping reagent for in vitro transcription of 5'capped mRNA to produce Cap 1 structure. Cap AG has been shown in the literature to provide a capping efficiency of up to 98%.
m7G(5')ppp(5')(2'OMeA)pG requires an AG initiator. m7G(5')ppp(5')(2'OMeA)pG typically provides >90% capped material generating a naturally occurring Cap 1 structure. |
DC58002 |
Cyclo(Gly-L-Pro)
|
Cyclo(Gly-(L)-Pro) shows immunostimulatory properties. Cyclo(Gly-l-Pro) exhibits potent inhibition of TNF-α release with the IC50 values of 4.5 ug/mL, respectively, it also exhibits significant diminution of IL-1β and IL-6 mRNA-expression levels and NO production. |
DC58001 |
BioE-1197
|
BioE-1197 is a novel Pask inhibitor. |
DC58150 |
PHD-1-IN-1
|
PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an “Arg367-out” pocket[1]. |
DC58312 |
GDC-6036
|
GDC-6036 is a novel oral KRAS G12C inhibitor. |
DC58308 |
ML-339
|
ML 339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM); 100-fold less active at the murine CXCR6 receptor (IC50 = 18 μM). Exhibits selectivity over CXCR5, CXCR4, CCR6 and APJ receptors (IC50 >79 μM). |