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STM2457

  Cat. No.:  DC53045   Featured
STM2457
Chemical Structure
2499663-01-1
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Field of application
STM2457 is in stock, and we can ship it immeidately. STM2457 is a potent inhibitor of METTL3/METTL14 catalytic activity with IC50 of 16.9 nM, Kd of 1.4 nM, respectively. STM2457 is highly specific for METTL3 and shows significant anti-leukaemic effect.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2499663-01-1
Chemical Name: STM2457
Synonyms: STM2457;STM-2457;STM 2457
SMILES: C1=CC=CC2=NC(C(=O)NCC3N=C4C=CC(CNCC5CCCCC5)=CN4C=3)=CC(=O)N12
Formula: C25H28N6O2
M.Wt: 444.23
Purity: >99%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: Small molecule inhibition of METTL3 as a strategy against myeloid leukaemia--Nature-Eliza Yankova, Wesley Blackaby-Published: 26 April 2021
MSDS
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