Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Endogenous Metabolite
Cat. No. Product name CAS No.
DC45304 N-Acetyloxytocin

N-Acetyloxytocin is isolated and characterized in the neurointermediate lobe of the rat pituitary (NIL) and their presence in several brain areas of the rat.

10551-48-1
DC45586 Kaempferol 3,4'-diglucoside

Kaempferol 3,4'-diglucoside is a flavonol isolated from the aqueous methanolic extract of norway spruce buds. Kaempferol 3,4'-diglucoside is identified in the needles.

71939-16-7
DC45587 Mevalonic acid 5-pyrophosphate tetralithium

Mevalonic acid 5-pyrophosphate (5-Diphosphomevalonic acid) tetralithium is an endogenous metabolite of the mevalonate pathway.

108869-00-7
DC45588 Creatine D3 hydrate

Creatine D3 hydrate is a deuterium labeled Creatine hydrate. Creatine hydrate is pivotal in energy metabolism of muscle and brain cells, both in physiological and in pathological conditions.

284664-86-4
DC45589 2'-Deoxyuridine 5'-monophosphate disodium Featured

2'-Deoxyuridine 5'-monophosphate disodium is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis.

42155-08-8
DC45590 Disodium 5'-dGMP Featured

2'-Deoxyguanosine 5'-monophosphate disodium (5′-dGMP disodium) is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative.

33430-61-4
DC45591 2′-Deoxyadenosine 5′-monophosphate disodium Featured

2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage.

2922-74-9
DC45851 7-Methylguanosine 5'-diphosphate sodium

7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues.

104809-16-7
DC45929 16α-Hydroxyestrone

16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease.

566-76-7
DC45954 Lacto-N-biose I

Lacto-N-biose I (Galβ1-3GlcNAc), as an endogenous metabolite, is an acceptor for the α1,2-fucosyltransferase enzyme from Helicobacter pylori.

50787-09-2
DC45970 S-Adenosyl-L-methionine iodide

S-(5'-Adenosyl)-L-methionine iodide (S-Adenosyl-L-methionine iodide) is an important methyl donor that is found in all living organisms.

3493-13-8
DC46052 S-Adenosyl-L-methionine D3

S-Adenosyl-L-methionine D3 (S-Adenosyl methionine D3) is a deuterium labeled S-Adenosyl-L-methionine. S-Adenosyl-L-methionine is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor.

68684-40-2
DC46062 Geranylgeranyl pyrophosphate

Geranylgeranyl pyrophosphate is a metabolite involved in protein geranylgeranylation. Geranylgeranyl pyrophosphate is the common precursor of  diterpenoids, for example, Paclitaxel. Geranylgeranyl pyrophosphate can be used for cancer research.

6699-20-3
DC46265 N4-Acetylcytidine triphosphate

N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription and can be incorporated into multiple templates.

1428903-57-4
DC46301 Vitamin K1 D7

Vitamin K1 D7 (Phylloquinone D7) is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

1233937-39-7
DC46483 Angiotensinogen (1-14), human TFA

Angiotensinogen (1-14), human TFA is a fragment of the renin substrate angiotensinogen. Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides.

DC46531 Folitixorin

Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research.

3432-99-3
DC46875 NHC-triphosphate tetraammonium

NHC-triphosphate tetraammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form. NHC-triphosphate tetraammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.

DC46876 NHC-diphosphate triammonium

NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form. NHC-triphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.

DC47031 2,8-Dihydroxyadenine

2,8-Dihydroxyadenine, an endogenous metabolite, can cause the formation of urinary crystals and kidney stones. 2,8-Dihydroxyadenine can be used to diagnose adenine phosphoribosyltransferase (APRT) deficiency.

30377-37-8
DC47032 3-Oxo-4,6-choladien-24-oic acid

3-Oxo-4,6-choladien-24-oic acid is an endogenous metabolite. 3-Oxo-4,6-choladien-24-oic acid exsists in the urine of patients with hepatobiliary disease.

88179-71-9
DC47034 Ebaresdax

Ebaresdax can inhibit peroxynitrite oxidation derived by SIN-1 and peroxynitrite mediated Cytotoxicity with IC50s of 3.7±0.80 and 0.13±0.02 uM, respectively.

1334471-39-4
DC47040 Larsucosterol

Larsucosterol is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis.

884905-07-1
DC47095 Larsucosterol sodium

Larsucosterol sodium is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis.

1174047-40-5
DC47116 Deutarserine

Deutarserine is a deuterium modified analog of endogenous D-serine (CTP 692), which is used in the research of adults with schizophrenia.

103292-62-2
DC47141 Triiodothyronine sulfate

Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.

31135-55-4
DC47214 Phosphoribosyl pyrophosphate pentasodium

Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP.

108321-05-7
DC47664 Indole-3-acetaldehyde

Indole-3-acetaldehyde inhibits Escherichia coli O157:H7 biofilm formation.

2591-98-2
DC47665 4-Hydroxytryptamine creatinine sulfate

4-Hydroxytryptamine creatinine sulfate, a tryptamine derivative, is a neurotransmitter agonist.

55206-11-6
DC47666 NMTCA

NMTCA (NMTPRO) is a sulfur-containing N-nitrosamino acid. NMTCA can be used as an indicator of endogenous nitrosation by gas chromatography-thermalenergyanalysis.

103659-08-1
DC47880 trans-Urocanic acid

trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function.

3465-72-3
DC47895 Sphinganine 1-phosphate

Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) is a polar sphingolipid metabolite that regulates cell migration, differentiation, survival and complex physiological processes.

19794-97-9
DC47959 Lignoceric acid

Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research.

557-59-5
DC48057 AFMK

AFMK, antioxidant metabolite of Melatonin, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. AFMK is a poorer scavenger. The pKa of AFMK at physiological pH is 8.7. Antioxidant capacity. AFMK improves the anti-tumor effect of Gemcitabine in PANC-1 cells through the modulation of apoptotic pathway.

52450-38-1
DC48067 1,7-Dimethyluric acid

1,7-Dimethyluric acid is the metabolite of caffeine.

33868-03-0
DC48236 4β-Hydroxycholesterol

4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation.

17320-10-4
DC48237 Dihomo-γ-Linolenic acid methyl ester

Dihomo-γ-Linolenic acid is an n-6 polyunsaturated fatty acid that is mainly metabolized to an anti-inflammatory eicosanoid, prostaglandin (PG) E1, via the cyclooxygenase (COX) pathway. Anti-inflammatory and anti-proliferative effects.

21061-10-9
DC48238 10(S),17(S)-DiHDHA

Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities.

871826-47-0
DC48239 12-OxoETE

12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via leukotriene B4 receptor or a common activation sequence.

108437-64-5
DC48240 Pregnanediol 3-glucuronide

Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species.

1852-49-9
DC48241 p-Cresyl sulfate

p-Cresyl Sulfate, a major uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver, existed in the blood of patients with chronic kidney disease (CKD).

3233-58-7
DC48242 ω-Muricholic Acid

ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.

6830-03-1
DC48243 C20 Ceramide

C20 Ceramide is a natural 20:0 ceramide that is abundant in the brain.

7344-02-7
DC48244 Delta-12-Prostaglandin J2

Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation.

87893-54-7
DC48245 3-Oxo-7-hydroxychol-4-enoic acid

3-Oxo-7-hydroxychol-4-enoic acid is an endogenous metabolite. 3-Oxo-7-hydroxychol-4-enoic acid may be an important indicator of a poor prognosis in hepatobiliary disease.

14772-95-3
DC48442 L-Tryptophan-13C11,15N2

L-Tryptophan-13C11,15N2 (Tryptophan-13C11,15N2) is the 13C- and 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.

202406-50-6
DC48443 L-Tryptophan-13C11

L-Tryptophan-13C11 (Tryptophan-13C11) is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.

202114-65-6
DC48444 Palmitoleic acid-13C16

Palmitoleic acid-13C16 is the 13C labeled Palmitoleic acid. Palmitoleic acid, a composition of fatty acid, is implicated in the prevention of death from cerebrovascular disorders in SHRSP rats.

2483735-57-3
DC48446 Linoleic acid-13C18

Linoleic acid-13C18 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

287111-25-5
DC48448 Glycine-13C2,15N

Glycine-13C2,15N is the 13C- and 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

211057-02-2
DC48449 Glycine-13C2

Glycine-13C2 is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

67836-01-5
DC48450 β-Alanine-13C3,15N

β-Alanine-13C3,15N (2-Carboxyethylamine-13C3,15N) is the 13C- and 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.

285978-07-6
DC48451 L-Alanine-13C3,15N

L-Alanine-13C3,15N (L-2-Aminopropionic acid-13C3,15N) is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

202407-38-3
DC48452 L-Cysteine 13C3,15N

L-Cysteine 13C3,15N is the 13C- and 15N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans.

202406-97-1
DC48453 L-Serine-13C3,15N

L-Serine-13C3,15N ((-)-Serine-13C3,15N) is the 13C- and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

202407-34-9
DC48454 L-Alanine-13C3

L-Alanine-13C3 (L-2-Aminopropionic acid-13C3) is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

100108-77-8
DC48455 L-Cysteine-13C3

L-Cysteine-13C3 is the 13C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans.

202114-66-7
DC48456 L-Aspartic acid-13C4

L-Aspartic acid-13C4 is the 13C-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.

55443-54-4
DC48457 L-Threonine-13C4,15N

L-Threonine-13C4,15N is the 13C- and 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed.

202468-39-1
DC48461 L-Valine-13C5,15N

L-Valine-13C5,15N is the 13C- and 15N-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid.

202407-30-5
DC48462 L-Methionine-13C5,15N

L-Methionine-13C5,15N is the 13C- and 15N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

202468-47-1
DC48463 L-Valine-13C5

L-Valine-13C5 is the 13C-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid.

55443-52-2
DC48464 L-Methionine-13C5

L-Methionine-13C5 is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

202326-57-6
DC48465 L-Ornithine-1,2,3,4,5-13C5 hydrochloride

L-Ornithine-1,2,3,4,5-13C5 hydrochloride is the 13C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

943962-21-8
DC48466 Itaconic acid-13C5

Itaconic acid-13C5 is the 13C labeled Itaconic acid. Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.

DC48467 L-Proline-13C5,1-15N

L-Proline-13C5,1-15N is the 13C- and 15N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

202407-23-6
DC48468 L-Glutamic acid-13C5,15N

L-Glutamic acid-13C5,15N is the 13C- and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

202468-31-3
DC48469 L-Glutamic acid-13C5

L-Glutamic acid-13C5 is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

55443-55-5
DC48470 L-Histidine-13C6,15N3 hydrochloride hydrate

L-Histidine-13C6,15N3 (H-His-OH-13C6,15N3) hydrochloride hydrate is the 13C- and 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

202468-43-7
DC48471 L-Histidine-13C6 hydrochloride hydrate

L-Histidine-13C6 (H-His-OH-13C6) hydrochloride hydrate is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

201740-88-7
DC48476 L-Lysine-13C6 dihydrochloride

L-Lysine-13C6 dihydrochloride is the 13C-labeled L-Lysine dihydrochloride. L-lysine dihydrochloride is an essential amino acid with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions.

201740-81-0
DC48477 L-Homoarginine-13C7,15N4 hydrochloride

L-Homoarginine-13C7,15N4 hydrochloride is the 13C- and 15N-labeled H-HomoArg-OH.HCl. H-HomoArg-OH.HCl is an endogenous metabolite.

2483830-23-3
DC48481 L-Tyrosine-13C9

L-Tyrosine-13C9 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

55443-60-2
DC48484 L-Tryptophan-13C

L-Tryptophan-13C (Tryptophan-13C) is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.

115709-68-7
DC48485 L-Tryptophan-1-13C

L-Tryptophan-1-13C (Tryptophan-1-13C) is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.

81201-92-5
DC48487 Orotidine 5′-monophosphate trisodium

Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT).

68244-58-6
DC48509 Myristic acid-13C3

Myristic acid-13C3 is the 13C labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

202114-49-6
DC48510 Lauric acid-13C

Lauric acid-13C is the 13C labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.

93639-08-8
DC48517 L-Tryptophan-15N2

L-Tryptophan-15N2 (Tryptophan-15N2) is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.

204634-20-8
DC48518 L-Tryptophan-15N

L-Tryptophan-15N (Tryptophan-15N) is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.

DC48535 Piliformic acid

Piliformic acid is a fungal metabolite found in the endophytic fungus Xylariasp sp.(No. 2508) from mangrove trees from the coast of the South China Sea.

98985-76-3
DC48559 Digalacturonic acid

Digalacturonic acid is a metabolite of pectin or pectic acid. Digalacturonic acid can be used for the co-crystallization of enzymes such as proteinase K.

5894-59-7
DC48560 Neohydroxyaspergillic acid

Neohydroxyaspergillic acid, an antibiotic, is active against some bacteriophages.

72598-34-6
DC48561 Valinotricin

Valinotricin is a fungal metabolite.

94899-85-1
DC48564 Myristic acid-13C

Myristic acid-13C the 13C is labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

57677-52-8
DC48566 L-Alanine-13C2

L-Alanine-13C2 (L-2-Aminopropionic acid-13C2) is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

65163-26-0
DC48567 Glycine-1-13C,15N

Glycine-1-13C,15N is the 13C- and 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

112898-03-0
DC48568 Glycine-2-13C,15N

Glycine-2-13C,15N is the 13C- and 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

91795-59-4
DC48569 Glycine-1-13C

Glycine-1-13C is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

20110-59-2
DC48570 Glycine-2-13C

Glycine-13C is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

20220-62-6
DC48589 Epsilon-(gamma-glutamyl)-lysine TFA

Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration.

DC48608 Aculene D

Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations.

2043948-38-3
DC48647 UDP-glucosamine disodium

UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which catalyzes the attachment of O-GlcNAc to proteins. O-GlcNAcase catalyzes the removal of O-GlcNAc from proteins. UDP-glucosamine (UDP-GlcNAc) disodium is the end product of the hexosamine biosynthesis pathway, which is regulated primarily by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT).

1355005-51-4
DC48679 Linoleic acid-13C1

Linoleic acid-13C1 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

98353-71-0
DC48682 Stearic acid-1-13C

Stearic acid-1-13C is the 13C labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.

85541-42-0
DC48698 Aspericin C

Aspericin C is a pyran derivative found in the marine-derived fungus Rhizopus sp. 2-PDA-61. Aspericin C shows cytotoxic activities against P388, A549, HL-60, and BEL-7420 cell lines (IC50=14.6, 7.1, 61.4, and 24.2 μM, respectively).

1216840-17-3
DC48716 Rostratin B

Rostratin B, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC50 of 1.9 μg/mL.

752236-17-2
DC48718 Rostratin A

Rostratin A is a cytotoxic disulfide found in the marine-derived fungus Exserohilum rostratum. Rostratin A shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with an IC50 of 8.5 μg/mL.

752236-16-1
DC48727 Penicitide A

Penicitide A is a marine secondary metabolite. Penicitide A shows moderate cytotoxicity against pathogen A. brassicae and the human hepatocellular liver carcinoma (HepG2) cell line.

1338332-27-6
DC48762 Aculene A

Aculene A is a unique type of norsesquiterpene from Aspergillus aculeatus.

2378379-28-1
DC48791 Rostratin C

Rostratin C, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC50 value of 0.76μg /mL.

752236-18-3
DC48806 L-Aspartic acid-1,4-13C2,15N

L-Aspartic acid-1,4-13C2,15N is the 13C- and 15N-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.

2483830-03-9
DC48807 L-Aspartic acid-1,4-13C2

L-Aspartic acid-1,4-13C2 is the 13C-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.

101247-29-4
DC48808 L-Alanine-1-13C,15N

L-Alanine-1-13C,15N (L-2-Aminopropionic acid-1-13C,15N) is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

141794-74-3
DC48809 L-Serine1-13C,15N

L-Serine1-13C,15N ((-)-Serine-13C,15N) is the 13C- and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

2483830-04-0
DC48810 DL-Alanine-1-13C

DL-Alanine-1-13C is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver.

102029-81-2
DC48811 DL-Alanine-3-13C

DL-Alanine-3-13C is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver.

131157-42-1
DC48812 L-Alanine-2-13C

L-Alanine-2-13C (L-2-Aminopropionic acid-2-13C) is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

62656-85-3
DC48813 L-Alanine-3-13C

L-Alanine-3-13C (L-2-Aminopropionic acid-3-13C) is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

65163-25-9
DC48814 L-Cysteine-3-13C

L-Cysteine-3-13C is the 13C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans.

201612-57-9
DC48815 L-Cysteine-1-13C

L-Cysteine-1-13C is the 13C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans.

224054-24-4
DC48816 L-Serine-2-13C

L-Serine-2-13C ((-)-Serine-2-13C) is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

89232-76-8
DC48817 L-Serine-13C

L-Serine-13C ((-)-Serine-13C) is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

89232-77-9
DC48824 ME-143

ME-143 is a second-generation tumor-specific inhibitor of NADH oxidase. ME-143 inhibits the WNT/β-catenin pathway in colorectal cancer cells. ME-143 has broadly active against cancers in vitro and in vivo.

852536-39-1
DC48828 1-Methoxyphaseollidin

1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.

65428-13-9
DC48845 NADP sodium hydrate

NADP sodium hydrate, a β-Nicotinamide adenine dinucleotide phosphate sodium salt, is a redox cofactor. NADP sodium hydrate is a key cofactor for electron transfer in the metabolism, being alternately oxidized (NADP+) and reduced (NADPH).

698999-85-8
DC48846 21-Deoxycortisol

21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia.

641-77-0
DC48850 Mycestericin G

Mycestericin G is a sphingosine-like fungal metabolite that exhibits immunosuppressive activity.

172519-49-2
DC48856 Fellutanine A

Fellutanine A, a diketopiperazine alkaloid, is a fungal metabolite from cultures of Penicillium fellutanum.

175414-35-4
DC48876 Protectin D1

Protectin D1, neuroprotectin D1 when generated by neural cells, is a member of a new family of bioactive products generated from docosahexaenoic acid. Protectin D1 is also a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models.

660430-03-5
DC48930 Fumiquinazoline D

Fumiquinazoline D, a secondary metabolite, is a mycotoxin.

140715-86-2
DC48937 Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate

Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate is a fungal metabolite.

81469-77-4
DC48950 Neoechinulin C

Neoechinulin C, an echinulin-related indolediketopiperazine alkaloid, protects the neuronal cells against paraquat-induced damage in a Parkinson’s disease model.

55179-54-9
DC48956 Estradiol 17-(β-D-Glucuronide) (sodium)

Estradiol 17-(β-D-Glucuronide) sodium, a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans.

15087-02-2
DC49006 Varioxepine A

Varioxepine A is a 3H-oxepine-containing alkaloid with a new oxa-cage found in the marine algal-derived endophytic fungus Paecilomyces variotii. Varioxepine A inhibits plant pathogenic fungus Fusarium graminearum.

1623451-72-8
DC49014 Glycohyocholic acid

Glycohyocholic acid(GHCA) is a glycine-conjugated form of the primary bile acid hyocholic acid.

32747-08-3
DC49062 Tryptoquivaline D

Tryptoquivaline D is a fungal metabolite from Aspergillus fumigatus.

60676-56-4
DC49090 Setosusin

Setosusin ((+)-Setosusin) is a fungal meroditerpenoid featuring a unique spiro-fused 3(2H)-furanone moiety.

182926-45-0
DC49110 Avellanin B

Avellanin B is a fungal metabolite with pressor effect.

110297-46-6
DC49116 L-Ornithine-1,2-13C2 hydrochloride

L-Ornithine-1,2-13C2 hydrochloride is the 13C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

224054-19-7
DC49117 D-Glucose-13C3-1

D-Glucose-13C3-1 (Glucose-13C3-1) is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

478529-32-7
DC49118 D-Glucose-13C3

D-Glucose-13C3 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

478529-47-4
DC49119 H-Tyr(3-I)-OH-13C6

H-Tyr(3-I)-OH-13C6 is the 13C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite.

2483735-06-2
DC49121 L-Tyrosine-13C6

L-Tyrosine-13C6 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

201595-63-3
DC49135 Cytoglobosin D

Cytoglobosin D, a cytochalasan derivative, displays cytotoxic activity toward the A-549 cell line (IC50=2.55 μM).

1221163-96-7
DC49136 Cytoglobosin C

Cytoglobosin C, a cytochalasan derivative, shows potent cytotoxicity against both SGC-7901 and A549 cell lines (IC50<10 μM).

1221163-94-5
DC49164 Burnettramic acid A aglycone

Burnettramic acid A aglycone is a fungal metabolite found in Aspergillus burnettii.

2396676-46-1
DC49190 Trichodecenin I

Trichodecenin I, a fungal metabolite, is a peptaibol composed of 7 amino acid residues.

141024-74-0
DC49202 β-Alanine-15N

β-Alanine-15N (2-Carboxyethylamine-15N) is the 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.

204451-53-6
DC49203 Sarcosine-15N

Sarcosine-15N (N-Methylglycine-15N) is the 15N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia.

DC49204 L-Serine-15N

L-Serine-15N ((-)-Serine-15N) is the 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

59935-32-9
DC49215 D-Glucose-13C2-4

D-Glucose-13C2-4 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

138079-87-5
DC49216 D-Glucose-13C2

D-Glucose-13C2 (Glucose-13C2) is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

201741-04-0
DC49219 Octanoic acid-13C4

Octanoic acid-13C4 (Caprylic acid-13C4) is the 13C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

159118-65-7
DC49222 Isovaleric acid-13C

Isovaleric acid-13C is the 13C labeled Isovaleric acid. Isovaleric acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human.

87994-84-1
DC49223 L-Valine-1-13C,15N

L-Valine-1-13C,15N is the 13C- and 15N-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid.

87019-54-3
DC49224 L-Valine-2-13C

L-Valine-2-13C is the 13C-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid.

73834-52-3
DC49225 L-Valine-1-13C

L-Valine-1-13C is the 13C-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid.

81201-85-6
DC49226 L-Methionine-13C

L-Methionine-13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

49705-26-2
DC49227 L-Methionine-1-13C

L-Methionine-1-13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.

81202-04-2
DC49228 L-Proline-13C

L-Proline-13C is the 13C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

81202-06-4
DC49229 L-Glutamic acid-5-13C

L-Glutamic acid-5-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

81202-00-8
DC49236 Cerebroside A

Cerebroside A is a single molecule cerebroside extracted and isolated from an edible mushroom. Cerebroside A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca²⁺ influx of NMDA receptors.

115681-40-8
DC49251 Cerebroside D

Cerebroside D, a glycoceramide compound, improves experimental colitis in mice with multiple targets against activated T lymphocytes.

113773-89-0
DC49264 Propane-1,2,3-triyl tripalmitate-13C3

Propane-1,2,3-triyl tripalmitate-13C3 is the 13C labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.

168294-57-3
DC49265 Propane-1,2,3-triyl tripalmitate-13C3-1

Propane-1,2,3-triyl tripalmitate-13C3-1 is the 13C labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.

201996-42-1
DC49275 Gamibetal

Gamibetal is the gamma-amino-beta-hydroxybutyric acid. Gamibetal has the potential for the research of epilepsy.

924-49-2
DC49281 L-Histidine-13C hydrochloride hydrate

L-Histidine-13C (H-His-OH-13C) hydrochloride hydrate is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

2483735-43-7
DC49282 D-Glucose-13C

D-Glucose-13C (Glucose-13C) is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

101615-88-7
DC49283 D-Glucose-13C-3

D-Glucose-13C-3 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

105931-74-6
DC49284 D-Glucose-13C-5

D-Glucose-13C-5 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

106032-62-6
DC49287 D-Glucose-13C-2

D-Glucose-13C-2 (Glucose-13C-2) is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

120388-24-1
DC49288 D-Glucose-13C-4

D-Glucose-13C-4 (Glucose-13C-4) is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

40762-22-9
DC49289 D-Glucose-13C-1

D-Glucose-13C-1 (Glucose-13C-1) is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.

84270-10-0
DC49292 L-Citrulline-13C

L-Citrulline-13C is the 13C-labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

94740-46-2
DC49294 L-Isoleucine-1-13C

L-Isoleucine-1-13C is the 13C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid.

81202-01-9
DC49300 Stephacidin B

Stephacidin B is a fungal metabolite. Stephacidin B shows in vitro cytotoxicity against a panel of human tumor cell lines. Stephacidin B shows the strongest cytotoxicity against testosterone-dependent prostate LNCaP cancer cells.

360765-75-9
DC49316 L-Ornithine-15N2 hydrochloride

L-Ornithine-15N2 hydrochloride is the 15N-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

360565-59-9
DC49322 (S)-L-Cystine-15N2

(S)-L-Cystine-15N2 is the 15N-labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.

DC49323 L-Histidine-15N3 hydrochloride hydrate

L-Histidine-15N3 (H-His-OH-15N3) hydrochloride hydrate is the 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

DC49324 L-Histidine-15N hydrochloride hydrate

L-Histidine-15N (H-His-OH-15N) hydrochloride hydrate is the 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

DC49335 L-Lysine-15N-1 dihydrochloride

L-Lysine-15N-1 dihydrochloride is the 15N-labeled L-Lysine. L-lysine is an essential amino acid with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions.

DC49344 L-Tyrosine-3,5-13C2

L-Tyrosine-3,5-13C2 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

70479-98-0
DC49345 Octanoic acid-13C

Octanoic acid-13C (Caprylic acid-13C) is the 13C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

59669-16-8
DC49361 L-Tyrosine-13C

L-Tyrosine-13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

110622-46-3
DC49362 L-Tyrosine-1-13C

L-Tyrosine-1-13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

81201-89-0
DC49363 L-Tyrosine-4-13C

L-Tyrosine-4-13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

81201-90-3
DC49380 L-Tyrosine-17O

L-Tyrosine-17O is the 17O-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

104931-15-9
DC49398 Hippuric acid-15N

Hippuric acid-15N (2-Benzamidoacetic acid-15N) is the 15N-labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.

93627-88-4
DC49409 Glucose oxidase

Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation.

9001-37-0
DC49766 Retinol-d4

Retinol-d4 (Vitamin A1-d4) is the deuterium labeled Vitamin A. Retinol is an endogenous metabolite.

118063-12-0
DC49767 Paraherquamide E

Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects.

125600-53-5
DC49768 11-epi-Chaetomugilin I

11-epi-Chaetomugilin I is a metabolite found in Chaetomium globosum. 11-epi-Chaetomugilin I exhibits significant cytotoxic activity against the murine P388 leukemia cell line, the human HL-60 leukemia cell line, the murine L1210 leukemia cell line, and the human KB epidermoid carcinoma cell line.

1319729-88-8
DC49769 Ebaresdax hydrochloride

Ebaresdax hydrochloride can inhibit peroxynitrite oxidation derived by SIN-1 and peroxynitrite mediated Cytotoxicity with IC50s of 3.7±0.80 and 0.13±0.02 uM, respectively.

1334385-87-3
DC49770 H2S Donor 5a

H2S Donor 5a is a cysteine-activated H2S donor. H2S plays important roles in biological systems. H2S Donor 5a is a useful tool in H2S research.

134861-13-5
DC49771 Magnesium acetate tetrahydrate

Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt. As a salt form of Magnesium, Magnesium acetate is one of the bioavailable forms of magnesium and forms a very water soluble compound. Magnesium acetate tetrahydrate can be used as an electrolyte supplementation or a reagent in molecular biology experiments.

16674-78-5
DC49772 Homovanillic acid-13C6,18O

Homovanillic acid-13C6,18O is the 13C-labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

202468-52-8
DC49773 5a-Pregnane-3,20-dione-d6

5a-Pregnane-3,20-dione-d6 is the deuterium labeled 5a-Pregnane-3,20-dione. 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

203850-92-4
DC49774 21-Deoxycortisol-d8

21-Deoxycortisol-d8 is the deuterium labeled 21-Deoxycortisol. 21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia.

2479914-04-8
DC49775 Thiamine pyrophosphate-d3

Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.

2483831-79-2
DC49776 5-Hydroxyindole-3-acetic acid-13C6

5-Hydroxyindole-3-acetic acid-13C6 is the 13C-labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.

2733322-34-2
DC49777 Nicotinamide-13C6

Nicotinamide-13C6 (Niacinamide-13C6) is the 13C-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.

2749910-55-0
DC49778 TMC-205

TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter.

403646-00-4
DC49779 7-Hydroxypestalotin

7-Hydroxypestalotin (LL-P880β) is a fungal metabolite.

41164-59-4
DC49780 Vitamin K1-d4

Vitamin K1-d4 (Phylloquinone-d4) is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

5172-18-9
DC49781 Cholic acid-13C

Cholic acid-13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

52886-36-9
DC49782 1,3,7-Trimethyluric acid

1,3,7-Trimethyluric acid is the metabolite of caffeine. The metabolic ratio 1,3,7-Trimethyluric acid to caffeine can be evaluated as a biomarker to describe variability in CYP3A activity in a cohort.

5415-44-1
DC49783 (Rac)-sn-Glycerol 3-phosphate

(Rac)-sn-Glycerol 3-phosphate is an a-site substrate analogue. (Rac)-sn-Glycerol 3-phosphate is bound to the a-site, the rate of reaction of indole and nucleophilic indole analogues with E(A-A) is strongly inhibited.

57-03-4
DC49784 Murideoxycholic acid

Murideoxycholic acid is a 6 beta-hydroxylated bile acid.

668-49-5
DC49785 Eicosapentaenoic Acid sodium

Eicosapentaenoic Acid (EPA)sodium is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid sodium exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid sodium activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid sodium can promote relaxation of vascular smooth muscle cells and vasodilation.

73167-03-0
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