2'-Deoxyuridine 5'-monophosphate disodium

  Cat. No.:  DC45589   Featured
Chemical Structure
42155-08-8
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Field of application
2'-Deoxyuridine 5'-monophosphate disodium is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis.
Cas No.: 42155-08-8
Chemical Name: 2'-Deoxyuridine 5'-monophosphate disodium salt
Synonyms: 2'-Deoxyuridine 5'-monophosphate disodium salt;2′-Deoxyuridine 5′-mono-phos-phate disodium salt;2’-DEOXYURIDINE-5'-MONOPHOSPHATE, DISODIUM SALT (DUMP.NA2);2'-Deoxyuridine 5'-mono-phos-phate disodium salt;2'-Deoxyuridine-5'-monophosphate, Disodium salt;dUMP;Deoxyuridine-5'-monophosphatedisodium salt;Disodium deoxyuridylic acid
SMILES: [Na+].OP(OCC1OC(N2C=CC(=O)NC2=O)CC1O)(=O)[O-]
Formula: C9H12N2NaO8P
M.Wt: 330.163714408875
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: 2'-Deoxyuridine 5'-monophosphate disodium is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis[1].
References: [1]. Zachary Newby, et al. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261. Biochemistry. 2006 Jun 20;45(24):7415-28.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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