Cat. No. | Product name | CAS No. |
DC10755 |
LSZ-102
Featured
LSZ102 is a potent, orally bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer. |
2135600-76-7 |
DC10072 |
LTI-291
Featured
LTI-291 is a Glucocerebrosidase (Gcase) activator for the treament of Parkinson's disease (PD). |
1919820-28-2 |
DC7583 |
Idalopirdine(Lu-AE-58054)
Featured
Lu AE58054 is an in-vitro potency and selectivity, in-vivo binding affinity and effect of the 5-HT(6)R antagonist with a Ki value of 0.83 nM. |
467459-31-0 |
DC9784 |
Lu AF21934
Featured
Lu AF21934 is a brain-penetrating positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4),reduces the harmaline-induced hyperactivity |
1445605-23-1 |
DC8287 |
Lubiprostone
Featured
Lubiprostone(SPI-0211;RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation. |
136790-76-6 |
DC23647 |
LUF7346
Featured
LUF7346 is a novel hERG allosteric modulator that slows IKr deactivation and positively shifting IKr inactivation. |
1821638-40-7 |
DC8611 |
Luliconazole
Featured
Luliconazole(NND 502) is an azole antifungal indicated for the topical treatment of interdigital tinea pedis. |
187164-19-8 |
DC22906 |
Lumateperone
Featured
Lumateperone (ITI-007) is a potent 5-HT2A antagonist (Ki=0.54 nM), postsynaptic D2 antagonist(Ki=32 nM), and SERT blocker (Ki= 61 nM). |
313368-91-1 |
DC11422 |
Lumateperone Tosylate
Featured
Lumateperone Tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a SERT blocker (Ki = 61 nM). |
1187020-80-9 |
DC3173 |
Lurasidone HCl
Featured
Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively. |
367514-88-3 |
DC9938 |
Lusutrombopag(S-888711)
Featured
Lusutrombopag(S-888711) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist being developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery. |
1110766-97-6 |
DC20271 |
LUT014
Featured
LUT014 is a novel BRAF agonist. |
2274819-46-2 |
DC12117 |
Luteolin 7-O-glucuronide (Luteolin 7-glucuronide4)
Featured
Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively. |
29741-10-4 |
DC7456 |
LX1606 Hippurate
Featured
LX1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. |
1137608-69-5 |
DC10754 |
LX2343
Featured
LX-2343 is a novel non-ATP competitive PI3K inhibitor, negatively regulating AKT/mTOR signaling, thus promoting autophagy, and increasing A-beta clearance. |
333745-53-2 |
DC7921 |
Sotagliflozin (LX-4211)
Featured
LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents. |
1018899-04-1 |
DC10828 |
LXH254
Featured
LXH254 is a potent CRAF inhibitor extracted from patent WO2018051306A1, Compound A. LXH254 also is a potent BRAF inhibitor. |
1800398-38-2 |
DC2072 |
LXR623
Featured
LXR-623 is a novel Liver X Receptor modulator |
875787-07-8 |
DC26012 |
LXS-196
Featured
LXS196 is a potent, selective and orally active protein kinase C (PKC) inhibitor, with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. It can be used for the treatment of uveal melanoma. |
1874276-76-2 |
DC8602 |
LY311727
Featured
LY 311727 is a specific group II sPLA2 (phospholipase A2 (PLA2)) inhibitor which has been reported to attenuate VEGF-mediated platelet-activating factor (PAF) synthesis in HUVEC and BAEC cells. |
164083-84-5 |
DC7944 |
LY2090314
Featured
LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50s of 1.5 nM and 0.9 nM for GSK-3α and GSK-3β respectively. |
603288-22-8 |
DC8435 |
LY2119620
Featured
LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors. |
886047-22-9 |