Lubiprostone|cas 136790-76-6|DC Chemicals

Cas No.:	136790-76-6
Chemical Name:	Lubiprostone
Synonyms:	Lubiprostone;7-[(1r,4r,6r,9r)-4-(1,1-difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo[4.3.0]non-9-yl]heptanoic acid;(11a)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid;13,14-dihydro-15-keto PD2;13,14-dihydro-15-keto Prostaglandin D2 Lipid Maps MS Standard;13,14-dihydro-15-keto-16,16-difluoro-PGE1;13,14-dihydro-15-keto-16,16-difluoro-Prostaglandin E1;13,14-Dihydro-15-keto-PGD2;13,14-Dihydro-15-ketoprostadlandin D2;13,14-dihydro-15-keto-prostaglandin D2;9ALPHA-HYDROXY-11,15-DIOXO-PROST-5Z-EN-1-OIC ACID;DK-PGD2;RU0211;RU-0211;SPI0211;SPI-0211;(11a,15R)-11,15-Epoxy-16,16-difluoro-15-hydroxy-9-oxo-prostan-1-oic acid;Amitiza;Lubiprostone hemiketal;7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid;(2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-heptanoic acid;7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid;Lubiprostone [USAN];Amitiza (TN);Bicyclic lubiprostone;Lubip
SMILES:	FC(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])([C@]1(C([H])([H])C([H])([H])[C@]2([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C(C([H])([H])[C@@]2([H])O1)=O)O[H])F
Formula:	C₂₀O₅F₂H₃₂
M.Wt:	390.4619
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Lubiprostone(SPI-0211;RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation.Target: OthersLubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). From Wikipedia.

References:

[1]. http://en.wikipedia.org/wiki/Lubiprostone

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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