Novel highly selective, soluble and cellular permeable inhibitor of the P. falciparum protease dipeptidyl aminopeptidase 1 (DPAP1)

Novel inhibitor of HIV replication, preventing the formation of the capsid core structure that encapsulates the viral genome and its associated enzymes, reversing transcriptase and integrase

Novel potent and selective inhibitor of Alk5 (TGFßR1), blocking the phosphorylation of Smad2 and Smad3 in HaCaT cells

Novel potent and selective ATP-competitive inhibitor of glycogen synthase kinase (GSK-3), targeting both isoforms GSK-3α and GSK-3β

Novel highly potent dual inhibitor of BRD9/BRD7

Novel RORγ antagonist for the treatment of autoimmune diseases

Non-ATP competitive inhibitor of JNK, targeting the JNK-JIP interaction

Novel potent, highly selective, and orally bioavailable CATHEPSIN C (CTSC, CatC) inhibitor

Novel nonpeptide angiotensin II receptor antagonist

Novel, highly selective and potent irreversible BTK inhibitor

Potent, selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase

Triple reuptake inhibitor (TRI)

Antilipidemic agent

GABAA receptor antagonist

Novel inhibitor of the TGF-β pathway, blocking the epithelial to mesenchymal transition

Partial agonist at dopamine D2 and serotonin 1A receptors

Novel selective heat shock protein 90 inhibitor, prodrug of CF2772

Selective Syk inhibitor

Novel, Selective, Potent, Reversible Bruton's Tyrosine Kinase (BTK) Inhibitor as an Orally Efficacious Agent for Autoimmune Diseases

Novel potent blocker of the NMDA receptor ion channel

Novel potent blocker of Nav1.2 sodium channels, protecting of brain tissue from ischemia

Natural Biliary Toxin, causing extrahepatic biliary atresia