Cell-permeable superoxide dismutase (SOD) mimetic

Novel inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins with potential antineoplastic activity

Novel JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients

Natural antioxidant and antidiabetic agent

Novel iminosugar, downregulatiing the interferon γ receptor by dengue virus

Natural potent antioxidant agent

Natural analogue of (-)-gambogic acid acting as a potent inhibitor of global predominant MRSA USA300

Potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors, and with moderate affinity for the 5-HT2 receptors

Natural antibacterial, antileishmanial, and antifungal agent

Potent and Specific PDE10A inhibitor

Novel mixed kappa-delta opioid receptor agonist with anti-cocaine properties and reduced side-effects in rats

Novel potent and selective microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor

Novel anti-cancer agent, being more potent and safer than conventional indomethacin

Novel selective class IIb histone deacetylase inhibitor (HDACi), dose-dependently decreasing the viability of Acanthamoeba trophozoites

Potent and selective COX-2 inhibitor

Specific estrogen receptor α (ERα) antagonist

Novel main protease (Mpro) inhibitor, inhibiting MHV-A29, HCoV-229E, FOPV replication, and SARS-CoV-2 viral cell entry

Novel Mps1 Kinase Inhibitor

Novel inhibitor of MPS1

Novel tubulin polymerization inhibitor

Novel Dual HDAC6 and Tubulin Inhibitor, Displaying Anti-tumor Ability in Human Cancer Cells

Novel mitochondrial permeability transition pore (mPTP) inhibitor