Ligand of the Grb7 SH2 domain, inhibiting the growth of MDA-MB-468 cancer cells

Novel substrate of ABCG2

Inhibitor of human tyrosyl-DNA phosphodiesterase 1 (TDP1)

Novel potent inhibitor of Huntington's disease (HD) pathogenesis via targeting CAG repeats RNA and Poly Q protein

Novel selective inhibitor of JAK3

Selective inhibitor of shp2 protein tyrosine phosphatase (PTP)

Selective non-lipid agonist of LPA2/3

Apoptosis inducer; Antitumor agent

Novel inhibitor of the second bromodomain (BD2) of the BET family protein BRD2

Novel potent SHP2 Inhibitor with Anti-Proliferative Activity in Breast Cancer Cell Lines

HIF-pathway inhibitor

Novel inhibitor of Nef-calnexin interaction

Inhibitor of the RUNX1-CBFβ interaction

Specific inhibitor of ERCC1-XPF with no effect on both HhaI and XPG

Novel potent and selective serotonin reuptake inhibitor (SSRI)

Selective G-quadruplex inducer of the human telomeric sequence; Stabilizer of the G-quadruplex formed by the MYC promoter sequence; Anti-neoplastic effects in wild-type p53, p53-mutant or p53-deficient human colon cancer cells.

Non-nucleoside reverse transcriptase inhibitor

Novel inhibitor of growth of intracellular Mycobacterium tuberculosis, inducing autophagy in differentiated THP-1 macrophages

Capturer of kinase-insertion domain receptor (KDR) from a solution, while allowing the captured KDR to bind with the solution-phase vascular endothelial growth factor (VEGF)

Novel inhibitor of ABCG2 transporter function

Novel potent SHP2 Inhibitor with Anti-Proliferative Activity in Breast Cancer Cell Lines

Novel 3C-like protease inhibitor of SARS-CoV-2