Poly(ADP-Ribose) Glycohydrolase (PARG) inhibitor

Novel Selective and Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase (hAMCase)

Potent agonist of the human 5-HT2A and 5-HT2C receptors

Natural potent antineoplastic agent with promising in vivo activity in glioblastoma and breast cancer through the activation of oxidative stress

Inhibitor of mitochondrial Lon protease and activator of DNA damage checkpoints

Specific inhibitor of vaccinia-related kinase 1 (VRK1)-mediated phosphorylation of barrier-to-autointegration factor (BAF)

Novel potent antileishmanial and antitrypanosomal agent, offering a more optimal balance of increased solubility, suitable metabolic stability, excellent oral bioavailability (100%), and strong in vivo efficacy in a visceral leishmaniasis mouse model (97%

Blue fluorescent labeling reagent

Irreversible and nonselective Monoamine_oxidase_inhibitor>monoamine oxidase inhibitor (MAOI)

Potent non-prostanoid inhibitor of platelet aggregation, acting via the prostacyclin receptor

Agonist of sst2, sst3 and sst5 somatostatin receptors

Novel highly potent and selective M3 muscarinic acetylcholine receptor antagonist and weak inverse agonist

Novel highly potent and selective M3 muscarinic acetylcholine receptor antagonist and weak inverse agonist

Novel highly potent and selective M3 muscarinic acetylcholine receptor antagonist

Novel highly potent and selective M3 muscarinic acetylcholine receptor antagonist

Cell-permeable, fluorescent Ca2+ indicator

Novel potent O-GlcNAcase (OGA) inhibitor (IC 50 : 46 nM), increasing the level of O-GlcNAcylated protein in cells and displaying suitable pharmacokinetic properties and brain permeability

Novel HSF1 inhibitor for target-based cancer therapy

Novel luciferin analog, enabling both sensitive and highly resolved imaging in vivo

Novel Bax activator, having greatest effect enhancing the pro-apoptotic activity of Bax with EC50 values of ∼0.1 μM and ∼0.9 μM, respectively, inducing cell death by a Bax/Bak-dependent mechanism

Novel orally bioavailable potent JAK-1 inhibitor

Inhibitor of type 1 and type 2A protein phosphatases; Tumor promotor