Inhibitor of type 1 and type 2A protein phosphatases; Tumor promotor

Inhibitor of type 1 and type 2A protein phosphatases; Tumor promotor

Dopamine antagonist as an atypical antipsychotic

Combination of the atypical antipsychotic olanzapine and opioid receptor antagonist samidorphan for treatment of adults with schizophrenia or bipolar I disorder

Natural inhibitor of the phosphorylation of protein kinase C ζ (PKCζ) at Thr410 site, reducing the activation of NF-κB using gain- and loss-of-function approaches in PE-treated cardiomyocytes, ameliorating pressure overload-induced cardiac hypertrophy

Potent antioxidant and neuroprotectant for treatment of Parkinson's disease, reducing reactive oxygen species (ROS) levels, inhibiting extracellular signal-regulated kinase (ERK) 1/2 phosphorylation, reducing rotenone-induced up-regulation of the proapopt

Novel specific agonist of odorant receptor 895 (Olfr895)

Novel Bruton's tyrosine kinase inhibitor, suppressing B cell and monocyte activation and ameliorates arthritis in a mouse model

Phosphodiesterase III inhibitor, augmenting cerebral blood flow by a direct vasodilator effect on cerebral arteries

Novel potent DAGL inhibitor, inhibiting collagen-, but not arachidonic acid-induced aggregation and TxA2 synthesis

Non-ATP-competitive Bcr-Abl inhibitor, potently inhibiting imatinib-resistant Bcr-Abl mutants such as T315I

Potent analogue of oncrasin-1 with antitumor activity mediated by JNK activation and STAT3 inhibition

Novel non-ATP-competitive inhibitor of BCR-ABL, overriding imatinib resistance

Novel enhancer of Schwann cell differentiation for treatment of peripheral nerve disorder

Protease inhibitor

Lipid A analog, inducing Th1-type immune response in tumor eradication and restoring nitric oxide production by peritoneal macrophages

Potent, orally available dual CysLT1 and CysLT2 receptor antagonist

Highly selective agonist of prostaglandin E2 receptor (EP2)

Novel selective EP2 receptor agonist, inducing relaxation of smooth muscle

Novel agonist of the prostaglandin PGE2 receptor EP4

EP(4)-selective antagonist

Novel selective EP3 receptor agonist