Novel Tau ligand, displaying high Tau binding, low MAO-A binding, high brain uptake, and fast and complete brain washout

Novel inhibitor of the PI3K/Akt/mTOR signaling pathways, activating P53 and inducing apoptosis

Novel Inhibitor of the PI3K-Akt Pathway, Inducing Autophagy of Female Germline Stem Cells

Highly potent ATP-competitive PI3Kdelta/Vps34 dual inhibitor

Novel potent PI3K inhibitor with a modified omipalisib structure

Novel PI3K inhibitor, synergizing with sorafenib in non-small cell lung cancer cells involving the Akt-S6 signaling.

Selective 5-HT4 receptor antagonist

Novel Subtype-Selective PPARbeta/delta Agonist

Potent and selective beta2-adrenoceptor agonist

Prodrug of GABA, used for treatment of neurogenic bladder in spinal and benign prostatic hyperplasia

Novel PI3K inhibitor, displaying potent preclinical activity against multiple myeloma

Natural activator of cryptic biosynthetic gene clusters (BGC), also acting as a potent inhibitor of monoamine oxidase B

Potent, highly selective, and orally bioavailable inhibitor of PIM-1 kinases

Novel potent PIM inhibitor

Antipsychotic agent

Inhibitor of PIP 4 Ks, efficiently killing transformed BJ cells, but not normal counterparts, displaying a strong selective lethality against Ras-activated or Ras-transformed cells

Partial agonist of benzodiazepine receptors

Antipsychotic prodrug, most notably used for schizophrenia

Antifungal antibiotic, showing inhibitory activity against fungi and yeasts, especially against Trichophyton

Novel potent in vitro and in vivo antifungal agent against azole-resistant Candida albicans

Natural nitric oxide (NO) production inhibitor

NSAID with better gastrointestinal (GI) tolerability