Novel metabotropic glutamate type 5 (mGlu5) receptor negative allosteric modulator (NAM)

Potent fluorescent α4β1/α9β1 inhibitor

Novel dual inhibitor of dihydroceramide desaturase (dhCerDS) and acid ceramidase (ACDase)

Novel dual inhibitor of dihydroceramide desaturase (dhCerDS) and acid ceramidase (ACDase)

Selective inhibitor of poly(ADP-Ribose) glycohydrolase (PARG)

Novel highly potent, selective, and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth

Novel Potent Broad-Spectrum Inhibitor of Influenza A Virus RNA-Dependent RNA Polymerase (RdRp)

Novel HIV-1 Integrase Inhibitor

Novel HIV-1 Integrase Inhibitor

Novel potent inhibitor of RECQL5-helicase activity, and stabilizing RECQL5-RAD51 physical interaction, leading to impaired HRR and preferential killing of RECQL5-expressing breast cancer

Novel Prenyltransferase Inhibitor with In Vitro and In Vivo Antibacterial Activity

Novel potent inhibitor of the supercoiling and ATPase reactions of DNA gyrase, inhibiting gyrase by preventing the binding of ATP

Novel inhibitor of the supercoiling and ATPase reactions of DNA gyrase, inhibiting gyrase by preventing the binding of ATP and showing selectivity against M. smegmatis.

Novel specific inhibitor of the ability of RegA to activate its target promoters, reducing expression of a number of proteins required for virulence

Novel selective antagonist of the mGlu5 receptor

Potent ultra short-acting synthetic unique opioid analgesic

5-HT3 antagonist and 5-HT4 agonist, also acting as a 5-HT2B antagonist

Novel bacterial methionyl t-​RNA synthetase (MRS) inhibitor, hampering Plasmodium growth very effectively

Selective 5-HT1A receptor agonist

Oxidation-reduction indicator in cell viability

Potent VR1 vanilloid receptor agonist, activating protein kinase C

Angiotensin-converting enzyme 2 (ACE2) activator, acting as a modulator on RAAS and KKS activation during COVID-19