3,4-Dibromo-Mal-PEG2-Amine TFA salt is a PEG Linker.

3,4-Dibromo-Mal-PEG2-Boc-Amine is a PEG Linker.

3,4-Dibromo-Mal-PEG4-t-butyl ester is a PEG Linker.

3,4-Dibromo-Mal-PEG8-t-butyl ester is a PEG Linker.

N-Mal-N-bis(PEG2-amine) TFA salt is a branched PEG derivative with a terminal maleimide group and two terminal amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

N-Mal-N-bis(PEG4-amine) TFA salt is a branched PEG derivative with a terminal maleimide group and two terminal amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

N-Mal-N-bis(PEG2-acid) is a branched PEG derivative with two terminal carboxylic acids and a maleimide group. The terminal carboxylic acids can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

N-Mal-N-bis(PEG4-acid) is a branched PEG derivative with two terminal carboxylic acids and a maleimide group. The terminal carboxylic acids can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

N-Mal-N-bis(PEG2-NHS ester) is a branched PEG derivative with a terminal maleimide group and two terminal NHS esters. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The NHS esters can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

N-Mal-N-bis(PEG4-NHS ester) is a branched PEG derivative with a terminal maleimide group and two terminal NHS esters. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The NHS esters can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Tri(Mal-PEG2-amide)-amine is a branched PEG derivative with three terminal maleimide groups. The maleimide groups will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

N-Mal-N-bis(PEG2-NH-Boc) is a branched PEG derivative with a terminal maleimide group and two terminal Boc protected amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The protected amines can be deprotected by acidic conditions.

N-Mal-N-bis(PEG4-NH-Boc) is a branched PEG derivative with a terminal maleimide group and two terminal Boc protected amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The protected amines can be deprotected by acidic conditions.

N-Mal-N-bis(PEG2-t-butyl ester) is a branched PEG derivative with a terminal maleimide group and two terminal t-butyl esters. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions.

Acid-PEG3-NHS ester is a PEG derivative containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Acid-PEG5-NHS ester is a PEG derivative containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Acid-PEG9-NHS ester is a PEG derivative containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

m-PEG3-succinimidyl carbonate is a PEG Linker.

m-PEG4-succinimidyl carbonate is a PEG Linker.

m-PEG5-succinimidyl carbonate is a PEG Linker.

m-PEG8-succinimidyl carbonate is a PEG Linker.

Mal-PEG4-Val-Cit-PAB-OH is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit group will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will only be released within the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

Mal-PEG4-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will only be released in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

Mal-amido-PEG2-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit group will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will only be released in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

Azido-PEG3-Val-Cit-PAB-OH is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit croup will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry.

Azido-PEG4-Val-Cit-PAB-OH is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit group will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry.

Azido-PEG3-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit group will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will be release only in the cell. The Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.

Fmoc-PEG4-Ala-Ala-Asn-PAB is a unique peptide cleavable ADC linker for antibody-drug-conjugation. The hydrophilic PEG spacer increases solubility in aqueous media.

Azido-PEG5-Ala-Ala-Asn-PAB is a unique peptide cleavable ADC linker for antibody-drug-conjugation. The Azido group is very reactive toward DBCO, BCN or other Alkyne groups for click chemistry. The hydrophilic PEG spacer increases the solubility in aqueous media.

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a unique peptide cleavable ADC linker for antibody-drug-conjugation. The hydrophilic PEG spacer increases solubility in aqueous media.

Azido-PEG4-Ala-Ala-Asn(Trt)-PAB is a PEG derivative conjugated with a peptide via an amide bond. The azide group on the PEG end enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a peptide reagent for ADC conjugation that possesses a cleavable peptide sequence. The hydrophilic PEG spacer increases solubility in aqueous media.

7-O-(Amino-PEG4)- paclitaxel is a PEG Linker that may be useful in the development of antibody drug conjugates (ADCs).

Bis-PEG3-PFP ester is a PEG Linker.

Bis-PEG4-PFP ester is a PEG Linker.

Bis-PEG5-PFP ester is a PEG Linker

Bis-PEG7-PFP ester is a PEG Linker.

2-(t-Butoxycarbonylamido)-1,3-bis(PFP-oxycarbonylethoxy)propane is a PEG Linker.

PEG2-bis(phosphonic acid) is a PEG Linker.

PEG3-bis(phosphonic acid) is a PEG Linker.

PEG3-bis-(ethyl phosphonate) is a PEG Linker.

PEG5-bis-(ethyl phosphonate) is a PEG Linker.

Bromo-PEG2-phosphonic acid is a PEG Linker.

Bromo-PEG3-phosphonic acid is a PEG Linker.

Bromo-PEG5-phosphonic acid is a PEG Linker

Bromo-PEG2-phosphonic acid diethyl ester is a PEG Linker.

Bromo-PEG3-phosphonic acid diethyl ester is a PEG Linker.

Bromo-PEG5-phosphonic acid diethyl ester is a PEG Linker.

Carboxy-PEG4-phosphonic acid is a PEG Linker.

Carboxy-PEG4-phosphonic acid ethyl ester is a PEG Linker.

t-butyoxycarboxy-PEG4-phosphonic acid ethyl ester is a PEG Linker.

Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid is a PEG Linker.

m-PEG2-phosphonic acid is a PEG Linker.

m-PEG4-phosphonic acid is a PEG Linker.

m-PEG5-phosphonic acid is a PEG Linker.

m-PEG9-phosphonic acid is a PEG Linker.

m-PEG4-(CH2)8-phosphonic acid is a PEG Linker.

m-PEG6-(CH2)8-phosphonic acid is a PEG Linker.

m-PEG8-(CH2)12-phosphonic acid is a PEG Linker.

m-PEG4-phosphonic acid ethyl ester is a PEG Linker.

m-PEG5-phosphonic acid ethyl ester is a PEG Linker.

m-PEG9-phosphonic acid ethyl ester is a PEG Linker.

m-PEG4-(CH2)8-phosphonic acid ethyl ester is a PEG Linker.

m-PEG6-(CH2)8-phosphonic acid ethyl ester is a PEG Linker.

m-PEG8-(CH2)12-phosphonic acid ethyl ester is a PEG Linker.

Propargyl-PEG3-phosphonic acid is a crosslinker containing a propargyl group and a phosphonic acid. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media.

Propargyl-PEG3-phosphonic acid ethyl ester is a PEG Linker.

S-acetyl-PEG3-phosphonic acid ethyl ester is a PEG Linker.

Thiol-PEG3-phosphonic acid is a PEG Linker.

PEG3-bis(phosphonic acid diethyl ester) is a PEG Linker.

PEG4-bis(phosphonic acid diethyl ester) is a PEG Linker.

PEG5-bis(phosphonic acid diethyl ester) is a PEG Linker.

[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester is a PEG Linker.

[4-(Diethoxy-phosphorylamino)-butyl]-phosphoramidic acid diethyl ester is a PEG Linker.

[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester is a PEG Linker.

Bis-PEG3-sulfonic acid is a PEG Linker.

Bis-PEG4-sulfonic acid is a PEG Linker

t-Butoxycarbonyl-PEG2-sulfonic acid is a PEG Linker

t-Butoxycarbonyl-PEG4-sulfonic acid is a PEG Linker.

t-Butoxycarbonyl-PEG5-sulfonic acid is a PEG Linker.

Tos-PEG2-t-butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG3-t-butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG4-t-butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG5-t-butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG6-t-Butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG7-t-Butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG9-t-butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG2-CH2CO2tBu is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG3-CH2CO2tBu is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG5-CH2CO2tBu is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG6-CH2CO2tBu is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG7-CH2CO2tBu is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Tos-PEG4-acid is a PEG derivative containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Tos-PEG3-CH2CO2H is a PEG derivative containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Tos-PEG4-CH2CO2H is a PEG derivative containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Tos-PEG5-CH2CO2H is a PEG derivative containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Propargyl-PEG2-Tos is a PEG derivative containing a tosyl group and a propargyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Propargyl-PEG3-Tos is a PEG derivative containing a tosyl group and a propargyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Propargyl-PEG4-Tos is a PEG derivative containing a tosyl group and a propargyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Propargyl-PEG5-Tos is a PEG derivative containing a tosyl group and a propargyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Tos-PEG4-methyl ester is a PEG Linker.

S-acetyl-PEG6-Tos is a PEG Linker.

N-Tos-N-(t-butoxycarbonyl)-aminoxy-PEG4-Tos is a PEG Linker.

Ms-PEG3-Ms is a PEG Linker.

Ms-PEG5-Ms is a PEG Linker.

Ms-PEG8-Ms is a PEG Linker.

Ms-PEG2-t-butyl ester is a PEG Linker.

Ms-PEG4-t-butyl ester is a PEG Linker.

PEG5-Ms is a PEG Linker.

Azido-PEG4-beta-D-glucose is a PEG derivative containing one azide group and one D-glucose group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. D-glucose increases solubility in aqueous media and increases the selectivity of the PEGylation reaction.

Azido-PEG4-alpha-D- mannose is a PEG Linker.

Azido-PEG4-tetra-Ac-beta-D-glucose is a PEG derivative containing one azide group and one D-glucose group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. D-glucose increases solubility in aqueous media and increases the selectivity of the PEGylation reaction.

Propargyl-PEG5-beta-D-glucose is a Click Chemistry-ready crosslinker containing a propargyl group and beta-D-glucose. The propargyl groups can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. D-glucose increases solubility in aqueous media and increases the selectivity of the PEGylation reaction.

Propargyl-PEG5-tetra-Ac-beta-D-glucose is a Click Chemistry-ready crosslinker containing a propargyl group and beta-D-glucose. The propargyl groups can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. D-glucose increases solubility in aqueous media and increases the selectivity of the PEGylation reaction.

Propargyl-PEG5-tetra-Ac-beta-D-galactose is a Click Chemistry-ready crosslinker containing a propargyl group and beta-D-galactose. The propargyl groups can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. D-galactose increases solubility in aqueous media and a the selectivity of the PEGylation reaction.

2,3,4,6-tetra-o-acetyl-alpha-galactosylpyranosyl bromide is a Sugar-PEGylation reagent.

TCO-PEG4-acid is a non-activated PEG derivative containing a TCO moiety and a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media and this reagent can be used to derivatize amine-containing molecules through a stable amide bond in the presence of activators (e.g. EDC, or HATU) .

TCO-NHS ester is an amine-reactive reagent containing the TCO moiety and a NHS ester. This reagent can be used to modify an amine-containing molecules. The specially formulated crystalline producty enables easy handling andan extended shelf life. TCO-NHS Ester is supplied as single axial (major) diastereomer.

TCO-PEG4-NHS ester is a PEG derivative containing a TCO moiety and a NHS ester. The hydrophilic PEG spacer increases water solubility and decreases steric hindrance during ligation. This reagent can be used to label antibodies, proteins, and other primary amine-containing macromolecules with TCO moiety.

TCO-PNB Ester is a biochemical.

TCO-amine hydrochloride is a simple building block containing a TCO moiety and a free amine. This reagent can be used to derivatize carboxyl groups or activated esters (e.g. NHS esters) with the TCO moiety through a stable amide bond in the presence of of activators (e.g. EDC, or DCC). The low mass weight will add minimal spacer to modified molecules.

TCO-C3-PEG3-C3-amine is is a simple PEG derivative containing a TCO moiety and a free amine. This reagent can be used to derivatize carboxyl groups or activated esters (e.g. NHS esters) with the TCO moiety through a stable amide bond in the presence of of activators (e.g. EDC, or DCC). Hydrophilic PEG spacer improves water solubility.

TCO-PEG4-biotin is a PEG Linker containing a TCO moeity.

TCO-OH is a biochemical.

Methyltetrazine-amine HCl salt possesses substantially improved stability compared to hydrogen substituted Tetrazine-Amine. This reagent can be used in a wider range of chemical transformations witih superior stability, enabling long-term storage in aqueous buffers. This reagent is supplied as HCl salt for improved stability and easy handling.

Methyltetrazine-propylamine HCl salt is a PEG derivative containing methyltetrazine and is one of the most stable tetrazines commercially available. Methyl group can improve the stability of methyltetrazine-Propylamine. This reagent is supplied as HCl salt for improved stability and easy handling.

Methyltetrazine-PEG4-amine HCl salt is a PEG derivative containing a free amine and a methyltetrazine group. It is one of the most stable tetrazines commercially available. Methyl group improves the stability and hydrophilic PEG spacer increases water-solubility. This reagent is supplied as HCl salt for improved stability and easy handling.

Tetrazine-Acid was found to have the fastest kinetics for bioorthogonal reactions where trans-cyclooctene (TCO) was the dienophile. The chemical stability of tetrazines is lower compared to methyltetrazines, but it is in acceptable range and thus can be applied for many applications.

Methyltetrazine-acid is a non-activated amine-reactive building block. In the presence of activators (e.g. EDC, or HATU), it can be used to deriviate amine-containing molecule via a stable amide bond. The low mass weight will add minimal spacer to modified molecules.

Methyltetrazine-PEG8-acid is a PEG Linker

Tetrazine-NHS ester is an NHS activated tetrazine derivative. The chemical stability of tetrazines is lower than methyltetrazines, but it is in acceptable range and thus can be applied for many applications. This reagent was found the fastest kinetics for bioorthogonal reaction with trans-cyclooctene (TCO) as the dienophile.

Tetrazine-Sulfo-NHS ester is a water-soluble NHS activated tetrazine derivative. This reagent was found to have the fastest kinetics for bioorthogonal reaction with trans-cyclooctene (TCO) as the dienophile. It can be used for simple and efficient labeling of antibodies, proteins and any other primary amine-containing macromolecules with the tetrazine moiety in 100% aqueous solution.

Methyltetrazine-NHS ester is an NHS actived building block containing a methyltetrazine group. It can react with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. Thus, this reagent can be used for modification of amine-containing molecule in organic media and the low mass weight will add minimal spacer to modified molecules.

Methyltetrazine-Sulfo-NHS ester is a water-soluble amine-reactive membrane impermeable labeling reagent. It is useful for applications that are intolerant of organic solvents and can be used to efficiently label antibodies, proteins, and other primary amine-containing macromolecules with the tetrazine moiety in 100% aqueous solution.

Tetrazine-PEG5-NHS ester is a PEG derivative containing a tetrazine group and an NHS ester. The hydrophilic PEG spacer increases water-solubility. It is one of the most reactive tetrazines commercially available. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics compared to methyl substituted tetrazines.

Methyltetrazine-PEG5-NHS ester is a PEG derivative containing a tetrazine group and an NHS ester. THe hydrophilic PEG spacer arm improves water solubility and is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond.

Methyltetrazine-PEG8-NHS ester is a PEG Linker.

Methyltetrazine-PEG5-alkyne is a PEG derivative containing an alkyne group and a hydrophilic PEG spacer. This reagent enables simple and efficient incorporation of a tetrazine moiety onto antibodies, cysteine-containing peptides, and other thiol-containing molecules. The alkynes can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages.

Methyltetrazine-PEG4-azide is a PEG derivative containing an azide group and a methyltetrazine moiety. The azide group enables Click Chemistry in organic solvents or aqueous media. The hydrophilic PEG spacer increases water-solubility and provides a long and flexible connection. This reagent can be used to efficiently incorporate tetrazine groups onto alkyne-modified peptides or oligonucleotides.

Methyltetrazine-PEG4-maleimide is a PEG derivative containing a maleimide group and a hydrophilic PEG spacer which increases water-solubility. The maleimide group specifically and efficiently reacts with thiols to form stable thioether bonds. This reagent can be used to incorporate a tetrazine moiety onto antibodies, cysteine-containing peptides, and other thiol-containing molecules.

Methyltetrazine-PEG4-NH-Boc is a PEG Linker.

Thiol-PEG2-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Thiol-PEG3-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Thiol-PEG4-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Thiol-PEG8-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Thiol-PEG3-t-butyl ester is a PEG derivative containing a thiol group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Thiol-PEG4-t-butyl ester is a PEG derivative containing a thiol group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Thiol-PEG6-t-butyl ester is a PEG derivative containing a thiol group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Thiol-PEG3-alcohol is a PEG derivative containing a thiol group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Thiol-PEG6-alcohol is a PEG derivative containing a thiol group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Bis-PEG3-thiol is a PEG derivative containing two thiol groups. The thiol groups react with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Bis-PEG5-thiol is a PEG derivative containing two thiol groups. The thiol groups react with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Lipoamido-PEG4-acid is a PEG Linker.

alpha-lipoic acid-NHS is a PEG Linker

Lipoamido-PEG2-alcohol is a PEG Linker.

Lipoamido-PEG3-alcohol is a PEG Linker.

Lipoamido-PEG3-azide is a PEG Linker.

Lipoamide-PEG3-Mal is a PEG Linker.

S-acetyl-PEG3-alcohol is a PEG Linker.

S-acetyl-PEG4-alcohol is a PEG Linker.

S-acetyl-PEG6-alcohol is a PEG Linker.

S-acetyl-PEG8-alcohol is a PEG Linker.

S-acetyl-PEG2-t-butyl ester is a PEG Linker.

S-acetyl-PEG3-t-butyl ester is a PEG Linker.

S-acetyl-PEG4-t-butyl ester is a PEG Linker.

S-acetyl-PEG6-t-butyl ester is a PEG Linker.

S-acetyl-PEG3-acid is a PEG Linker.

S-acetyl-PEG4-propargyl is a PEG Linker.

SPDP-PEG4-acid is a PEG Linker.

SPDP-PEG8-acid is a PEG Linker.

SPDP-PEG4-NHS ester is a PEG Linker.

SPDP-PEG6-NHS ester is a PEG Linker.

(2-pyridyldithio)-PEG4-alcohol is a PEG Linker.

(2-pyridyldithio)-PEG4-propargyl is a PEG Linker.

(2-pyridyldithio)-PEG2-t-butyl ester is a thiol PEG Linker.

Alcophosphamide is a urinary metabolite of cyclophosphamide which may be used in proteomics research.

Glyceryl monooleate is a biochemical which may be used as a nanocarrier for drug delivery.

Aldrin-transdiol is a metabolite of dieldrin. Aldrin-transdiol may be used in insecticides.

Tiropramide hydrochloride is a smooth muscle antispasmodic agent which has been shown to to have some efficacy in normalizing intestinal transit time and in inducing symptomatic relief for Irritable Bowel Syndrome (IBS) patients.

Aloesin is a competitive tyrosinase inhibitor. As an Aloe chromone, Aloesin has previously been formulated with an aloe polysaccharide to give a composition called Loesyn, where it showed significant impact in reducing glycosylated hemoglobin, fasting blood glucose, fructosamine and plasma insulin level in humans. This molecule has also been shown to modulate melanogenesis and have some anti-inflammatory effects in rats.

Aloperine is an alkaloid with diverse biological activities including antiviral, anticancer, antioxidant, and anti-inflammatory actions. It inhibits HIV-1 replication and envelope-mediated cell-cell fusion in vitro. Aloperine also inhibits the growth of HL-60, U937, and K562 leukemia cell lines.

Memantine is an amantadine derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent and has may be used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by blocking NMDA receptors.

AM 6201, also known as Reductiomycin, is an alkaloid originally derived from Streptomyces xanthochromogenus that has been shown to exhibit antitumor activity against Ehrlich ascites carcinomas in mice.

AM-1172 is an endocannabinoid analog specifically designed to be a potent and selective inhibitor of AEA uptake that is resistant to FAAH hydrolysis.

AMD-8664 is an HIV entry inhibitor which was being developed by AnorMED in the US in conjunction with the Rega Institute of Leuven. AMD-8664 works by antagonizing the HIV-1 entry co-receptor CXCR4. AMD-8664 may be useful for the clinical treatment of HIV-1-infected patients, especially at the late stage of treatment for AIDS patients developing multi-drug-resistant strains.

Amlodipine besilate impurity G is a biochemcical.

Amlodipine besilate impurity D is a biochemical.

Amlodipine besilate impurity E is a biochemical.

Amlodipine besilate impurity F, also known as Amlodipine Dimethyl Ester, is a biochemical.

Amlodipine besilate impurity B is a biochemical.

Amthamine is a selective histamine H2 receptor agonist which does not stimulate activity of H1 and H3 receptors. Similar to histamine, Amthamine inhibits receptor -mediated eosinophil peroxidase. Amthamine has been shown to suppress the release of serotonin and has been used to study the involvement of H1 and H2 receptors on ion secretion.

Ambazone is an antiseptic agent with potential antibacterial and antileukemic activity. Although the exact mechanism of action remains unclear, ambazone appears to interfere with the membrane-bound nucleotide system by increasing the intracellular concentration of cAMP in leukemia cells and macrophages, which potentially contributes to this agent's antineoplastic activity.

beta-Amyrin is a molecule which has been shown to exhibit long-lasting antinociceptive and anti-inflammatory properties. beta-Amyrin activates cannabinoid receptors CB1 and CB2 and inhibits the production of cytokines and expression of NF-κB, CREB and cyclooxygenase 2.

Chloramben-sodium is an herbicide.

Amiloride is a medication typically used with other medications to treat high blood pressure or swelling due to heart failure or cirrhosis of the liver. In the USA, this drug is available via prescription only.

Amisometradine is a diuretic which may be used in the treatment of congestive heart failure.

Anatabine is one of the minor alkaloids found in plants in the Solanaceae family, which includes the tobacco plant and tomato. Anatabine may be useful for treating nicotine addiction and inflammation, Alzheimer's Disease, thyroiditis, and multiple sclerosis.

Alkannin is an antioxidant. It is also known to have wound healing, antitumor, and antithrombotic properties.

Amcinafal is a topical steroidal anti-inflammatory.

Nifenazone is a drug used as an analgesic for a number of rheumatic conditions.