Antazoline phosphate is an antihistamine with anticholinergic properties used to relieve nasal congestion and the symptoms of allergic conjunctivitis. Antazoline is an ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents the typical allergic symptoms caused by histamine activities on capillaries, skin, mucous membranes, and gastrointestinal and bronchial smooth muscles.

Methenamine is an anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH.

Pyrantel pamoate is a broad spectrum antinematodal anthelmintic.

Methylthiouracil is thiourea antithyroid agent that inhibits the synthesis of thyroid hormone. It is used in the treatment of hyperthyroidism.

Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage, with an IC50 of 80 nM. Toyocamycin (Vengicide) induces apoptosis. Toyocamycin (Vengicide) shows no effect on IRE1α auto-phosphorylation[1].

Verrucarin A is an antibiotic which has been shown to inhibit proliferation of prostate cancer cells by inhibiting prosurvival Akt/NF-kB/mTOR signaling.

APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.

Apomorphine hydrochloride is a Dopamine (D1 and D2) receptor agonist which may be effective in the treatment of Parkinson's disease.

APP-CHMINACA is a synthetic cannabinoid (CB) featuring a 1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (CHMINACA) base. It displays a 10-fold greater affinity for the central CB1 receptor than that of JWH 018.

Apronalide, also known as Allylisopropylacetylurea or Apronal, is a hypnotic/sedative drug of the ureide (acylurea) group which may induce cytochrome P-450 through barbiturate-like activity. Though it is not a barbiturate, apronalide is similar in structure and action to the barbiturates, although considerably milder in comparison. Upon the finding that it caused patients to develop thrombocytopenic purpura, apronalide was withdrawn from clinical use except in Japan.

Apovincamine is a vinca alkaloid and a chemical precursor of Vinpocetine, a derivative of Vincamine with vasodilating activity.

AQ-RA 741 is a tricyclic antimuscarinic drug.

Arbaprostil is a synthetic prostaglandin E analog that protects gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and can inhibit the growth of experimental tumors. Arbaprostil is a prodrug for the potent PGE2.

Arecoline is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice.

Ibuprofen lysine is a non-steroidal anti-inflammatory drug (NSAID). The lysine suspension of Ibuprofen may act more quickly and effectively than base Ibuprofen.

Moxisylyte hydrochloride is an alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents.

Harmaline is a beta-carboline alkaloid isolated from seeds of PEGANUM. It is a psychoactive indole with stimulating activities achieved, in part, through inhibition of monoamine oxidases. Harmaline induces tremor in mice through the N-methyl-D-aspartate (NMDA) receptor, at which harmaline may act as an inverse agonist.

(±)-Shikonin is a naphthazarin with antineoplastic and angiogenesis inhibiting activities.

ar-Turmerone is an immunomodulator which has exhibited cytotoxicity toward various cell lines such as the K562, L1210, U937 and RBL-2H3 cell lines.

Ticagrelor metabolite M5, also known as AR-C133913XX, is a metabolite of Ticagrelor which is the first reversible oral P2Y12 receptor antagonist. Ticagrelor provides faster and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).

Hydrocortisone sodium succinate is a glucocorticoid which is used to alleviate allergic reactions, particularly those of the skin and gums.

Heptaminol hydrochloride is an amino alcohol used as a myocardial stimulant, vasodilator, and to relieve bronchospasm. Its most common therapeutic use is in orthostatic hypotension. The mechanism of heptaminol's therapeutic actions is not well understood although it has been suggested to affect catecholamine release or calcium metabolism.

Aranorosin is an antibiotic which has been shown to circumvent arbekacin-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2″).

alpha-Artemether is a Quinghaosu derivative which shows antimalarial and antifungal activity.

Artemisitene is an antimalarial agent and the oxidized form of Artemisinin. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinic acid, Artemisinin B, Artemisitene, etc.

Norepinephrine bitartrate salt is an adrenergic neurotransmitter.

Aseanostatin P1 is a fatty acid which inhibits myeloperoxidase (MPO) release from human polymorphonuclear leukocytes.

Aseanostatin P5 inhibits myeloperoxidase (MPO) release from human polymorphonuclear leukocytes.

Hadacidin is an inhibitor of AMP synthesis. Hadacidin and hadacidin analogues have anticancer activity and activity against adenylosuccinate synthetase.

Aspalatone is an anti-platelet aggregator (antithrombotic) that has been shown to prolong bleeding time in the mouse model. Aspalatone generates antioxidant and neuroprotective effects against kainic acid-induced epilepsy.

ent-Atorvastatin is a selective and competitive HMGCR (HMG-CoA reductase) inhibitor

Atpenin A5, an antifungal antibiotic, is an ubiquinone-binding site inhibitor of succinate dehydrogenase. Atpenin A5 has cardioprotective effects against simulated ischemia-reperfusion injury in cardiomyocytes.

Chlortetracycline is a broad-spectrum antibiotic tetracycline with a 7-chloro substitution. It inhibits growth of both Gram-positive and Gram-negative bacteria. It acts by inhibiting protein synthesis.

Aurapten is a coumarin with anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis. Aurapten may also be useful in the treatment of Alzheimer’s disease by inhibiting β-secretase (BACE1) activity.

Avarol induces apoptosis in pancreatic ductal adenocarcinoma cells by activating PERK-eIF2α-CHOP signaling. Avarl also acts as a competitive AChE inhibitor which are non-hepatotoxic and neuroprotective agents for Alzheimer's disease.

Avarone is a cytostatic agent which has potent antileukemic activity in vitro. Avarone also displays antibacterial and antifungal activities against a limited range of microorganisms.

Averantin is an Aflatoxin B(1) precursor.

AX-048is a potent group IVA cPLA2 inhibitor. The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes.

Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin

SQ-28429 is a synthetic monobactam.

(S)-Azelastine hydrochloride is an antihistamine which has been shown to down-regulate H1R, M1R and M3R levels. This compound has also been shown to inhibit HNEpC proliferation.

(R)-Azelastine hydrochloride is an antihistamine which has been shown to down-regulate H1R, M1R and M3R levels. This compound has also been shown to inhibit HNEpC proliferation.

Rasagiline is a selective and irreversible propargylamine inhibitor of monoamine oxidase type-B (MAO-B) that is not metabolized to amphetamine derivatives. Rasagiline exhibits neuroprotective and antiapoptotic activity against ischemia and several neurotoxins, including SIN-1, MPTP, 6-hydroxydopamine, and N-methyl-(R)-salsolinol.

S-Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). S-diclofenac may protect against doxorubicin-induced cardiomyopathy by ameliorating cardiac gap junction remodeling.

Butamirate citrate is an anti-tussive which may be used in the treatment of non-productive (dry) cough.

Cyclocumarol is an anticoagulant similar to but less potent than warfarin. This product may cause hemorrhaging if used indiscriminately.

Triprolidine hydrochloride anhydrous is a Histamine H1 antagonist used in allergic rhinitis, asthma, and urticaria.

N2-Acetylaciclovir, also known as Aciclovir EP Impurity F, is an impurity of Aciclovir.

Doxycycline monohydrate is a synthetic tetracycline derivative with similar antimicrobial activity.

Dexrazoxane hydrochloride is a cardioprotectant. Studies have shown that usage of this drug before anthracycline chemotherapy in pediatric patients with AML may improve cardiac function indices such as ejection fraction and shortening fraction. Adding dexrazoxane to doxorubicin in adjuvant therapy patients may lead to higher rates of bone marrow suppression, more febrile neutropenia events, and dose reductions.

Adrenone hydrochloride displays antineoplastic activity and has been shown to inhibit growth of Ehrlich ascites tumors in mice.

Adipostatin A is an inhibitor of glycerol-3-phosphate dehydrogenase (GPDH). It prevents triglyceride accumulation in 3T3-L1 cells and is cytotoxic against fibroblast carcinoma KB cell lines. It also shows larvicidal activity against A. aegypti.

alpha-Cypermethrin is a synthetic pyrethroid pesticide.

Abamectin is a mixture of the macrocyclic lactones Avermectin B1a and Avermectin B1b. It has both insecticidal and anthelmintic actions and is used in both agriculture and veterinary medicine. Abamectin can inhibit nicotinic acetylcholine receptors of worms and can also inhibit chikungunya and yellow fever viruses. It is sometimes used for mosquito control.

Penicillin G procaine is a semisynthetic antibiotic prepared by combining penicillin G with Procaine.

IMS2186 is an anti-proliferative and anti-angiogenic agent. IMS2186 blocks the cell cycle at G2 and inhibits the production of PGE2/TNF-α. IMS2186 inhibits cell growth in vitro in tumor cells, non-transformed fibroblasts, and retinal pigment epithelial cells. IMS2186 inhibits angiogenesis (IC50 = 0.1 μM) and cell migration. Intraocular injection of IMS2186 could be a long-lasting effective treatment for CNV (choroidal neovascularization) in AMD (age-related macular degeneration) with a reduction in scarring and related visual loss.

ML230 is a specific inhibitor of the ABC-binding cassette trasporter BCRP (MRP-1; ABCG2). The compound ML 230 is 36-fold selective for BCRP over MDR-1 (Pgp; ABCB1) with IC50 values of 0.013 and 4.7 mM, respectively.

L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggregation studies, L2-b inhibits metal-induced Aβ aggregation, and also promotes the dissociation of Ab aggregates in homogenates of human AD brain samples.

(S)-Apomorphine Hydrochloride is a Dopamine (D1 and D2) receptor agonist which may be effective in the treatment of Parkinson's disease.

AMBMP hydrochloride is a Wnt canonical signaling activator and tubulin polymerization inhibitor.

Emetine is a drug used as both an anti-protozoal and to induce vomiting. It is produced from the ipecac root. It takes its name from its emetic properties. Emetine protects mice from enterovirus infection by inhibiting viral translation. Emetine Synergizes with Cisplatin to Enhance Anti-Cancer Efficacy against Lung Cancer Cells. Emetine exhibits anticancer activity in breast cancer cells as an antagonist of Wnt/β?catenin signaling. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.

Lansoprazole sulfide is an impurity of Lansoprazole -- a gastric pump inhibitor.

Axitinib sulfoxide is a major metabolite of Axitinib --- a VEGFR tyrosine kinase inhibitor. Axitinib may be useful in cancer therapy.

Precocene II is an antiallotropin compound capable of inhibiting juvenile hormone biosynthesis. Precocene II has antibacterial, antifungal, insecticidal, and antioxidant activities.

AGN-191129, also known as Prostaglandin F2α alcohol methyl ether (PGF2α-OMe), is an analog of PGF2α in which the C-1 carboxyl group has been replaced by an O-methyl ether. The compound is reported to retain ocular hypotensive properties, but the receptors which mediate this activity have not been clearly documented.

Muscimol is a neurotoxic isoxazole obtained by decarboxylation of Ibotenic Acid. Muscimol is a potent agonist of GABA-A receptors and is used mainly as an experimental tool in animal and tissue studies.

Agroclavine is a clavine type of ergot alkaloid with D1 dopamine and a-adrenoceptor agonistic properties.

Vesamicol hydrochloride, (+/-)- is an inhibitor of acetylcholine transport.

Etaqualone is an analytical reference standard categorized as a quinazolone.

AT-1015 HCl anhydrous is a serotonin (5-HT)2 receptor antagonist that blocks vascular and platelet 5-HT2A receptors.

AT-9283 L-lactate is an aurora kinase inhibitor.

Chlorfluazuron is a chitin synthesis inhibitor. Chlorfluazuron is commonly used in agriculture as an insect growth regulator for controlling the major insect pests in crops

Febrifugine dihydrochloride is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases.

Metoprolol acid is a pharmacologically inactive urinary metoprolol metabolite.

Cloxacillin Sodium is a semi-synthetic antibiotic that is a chlorinated derivative of Oxacillin. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase.

Sulfentrazone, also known as FP-846, is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.

Aureothricin is a dithiolopyrrolone antibiotic that exhibits broad-spectrum antimicrobial activity against many Gram-positive and Gram-negative bacteria as well as strains of M. tuberculosis. It is also reported to inhibit tumor angiogenesis, blocking activity of the vitronectin receptor integrin αvβ3.

Aureothin is a natural nitroaryl-substituted polyketide that exhibits antitumor, antifungal, and insecticidal activities. It is a non-competitive inhibitor of NADH:ubiquinone oxidoreductase.

Thioperamide is an HRH4 antagonist and selective HRH3 antagonist capable of crossing the blood–brain barrier. Thioperamide negatively regulates the release of histamine and enhances the activity of histaminergic neurons by blocking autoreceptors. Its action on H3 is thought to promote wakefulness and improve memory consolidation.

Methimepip dihydrobromide is a histamine agonist which is highly selective for the H3 subtype. It is the N-methyl derivative of immepip.

Immethridine (hydrobromide) is a histamine agonist selective for the H3 subtype.

Impentamine dihydrobromide is a histamine antagonist selective for the H3 subtype.

GT-2016 is an H3 antagonist that may play a role in cognition.

Talopram hydrochloride is a the HCl salt of Talopram -- a selective norepinephrine reuptake inhibitor (NRI). Along with talsupram, talopram is structurally related to the selective serotonin reuptake inhibitor (SSRI) citalopram, as well as to melitracen.

AICAR, also known as AICA riboside, is a purine precursor with antineoplastic activity. It is important in treatment of metabolic diseases such as type 2 diabetes as well as possible treatment of various cancer types.

Tylvalosin is an antibacterial drug.

Ponasterone A is an analog of 20-hydroxy ecdysone. Ecdysteroids act as inducers of ecdysone-inducible mammalian expression systems.

Zoxazolamine is a uricosuric and muscle relaxant of which the mechanism of action is not well understood.

Cupferron is a superoxide dismutase inhibitor.

Caffeic acid provides protection against genotoxicity of DMBA.

Gallein is a Gβγ subunit signalling inhibitor which has been shown to inhibit metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand.

Triphenyltetrazolium bromide may be useful in the detection of experimental cerebral infarction and biochemical analysis.

Ethylenediaminediacetic acid (EDDA) is a derivative of two molecules of glycine wherein the amines are linked.

TES free acid is a structural analog to Tris buffer. It is one of the ethanesulfonic acid series of biological buffers developed by Good et al. Good's buffer criteria: midrange pKa, maximum water solubility and minimum solubility in all other solvents, minimal salt effects, minimal change in pKa with temperature, chemically and enzymatically stable, minimal absorption in visible or UV spectral range, and easily synthesized. TES probably exists in solution as a zwitterion.

Ibacitabine is an antiviral drug.

Profluralin is an herbicide.

Leucinol is a reversible inhibitor of protein synthesis and starting material for the synthesis of aminopeptidase N and phospholipase A2 inhibitors.

Camptothecin sodium selectively inhibits the nuclear enzyme DNA Topoisomerase, Type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.

Nicarbazin is an equimolar complex of 4,4'-Dinitrocarbanilide and 2-Hydroxy-4,6-dimethylpyrimidine. It is used as a coccidiostat for poultry.

Benzylurea is a competitive inhibitor of cytokinin oxidase/dehydrogenase.

Norspermine is a polyamine analogue which may be useful in the treatment of non-small cell lung carcinoma and breast cancer.

Berberine sulfate is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids.

Melarsen oxide is a glutathione reductase inhibitor.

Methylguanidine hydrochloride is a biochemical that can be used in the synthesis of biaryl derivatives which were evaluated as BACE1 inhibitors.

Pyruvic acid semicarbazone is a biochemical.

Amidinomalonamide hydrochloride is a chemical reagent used in the preparation of pyrimidooxazines used as DGAT1 inhibitors. This drug has potential use as an anti-obesity treatment.

Tyramine hydrochloride is an indirect sympathomimetic. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and monoamine oxidase, so it prolongs the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals. Tyramine may be a neurotransmitter in some invertebrate nervous systems.

Gibbs reagent is a universal thin-layer chromatographic visualization reagent.

Canavanine sulfate is a biochemical with antimutagenic activity. This product has been shown to potentiate the cytotoxicity of doxorubicin and cisplatin in arginine deprived human cancer cells

Fluorometholone acetate is an anti-inflammatory that may be useful in the reduction of ocular inflammation.

Rhododendrol, (+/-)-, is an aromatic compound that may be useful in the treatment of hepatic diseases. However, this product is a known pro-oxidant which can be toxic to melanocytes.

Meldrum's acid is an antimicrobial agent of deodorant composition.

Fluprostenol, (+)-, is an analog of Prostaglandin F2α with potent FP receptor agonist activity.

AL-6598 is a DP prostaglandin receptor agonist which may lead to sustained intraocular pressure reduction. This bioactivity may be useful in the treatment of glaucoma.

Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity.

Albendazole sulfone is a metabolite of Albendazole, an anthelmintic, antibiotic, and antiparisitic.

Oxyquinoline sulfate is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.

Chloropyramine hydrochloride may be useful in the treatment of invasive breast cancer.

Mecobalamin is a biologically active analog of Vitamin B12.

Sethoxydim is an herbicide.

Trimeprazine tartrate is a phenothiazine derivative that is used as an antipruritic.

Alinidine is an anti-arrythmic that reduces heart-rate without blockade of beta-adrenoceptors.

Triticonazole is a fungicide.

Ceftezole sodium is a broad-spectrum cephalosporin antibiotic active gram-positive and gram-negative bacteria except Pseudomonas aeruginosa, Serratia marcescens and Proteus vulgaris. The bactericidal activity of ceftezole results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Ceftezole has been shown to exhibit potent alpha-glucosidase inhibitory activity.

Altanserin hydrochloride is a compound that binds to the 5-HT2A receptor. Labeled with the isotope fluorine-18, it is used as a radioligand in positron emission tomography (PET) studies of the brain.

Antioxidant ZMB is an antioxidant.

Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase. This enzyme crucial to the metabolism of alcohol and is suitable for aldehyde dehydrogenase (ALDH) related research.

Altinicline maleate is a potent neuronal nicotinic ACh receptor agonist that improves cognitive function in a MPTP-induced model of Parkinson's Disease in vivo.

Capsanthin is a carotenoid found in red paprika that has diverse biological activities. It reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and phosphorylation of ERK and p38 and prevents inhibition of gap-junction intracellular communication in WB-F344 rat liver epithelial cells. Capsanthin reduces the number of colonic aberrant crypt foci and preneoplastic lesions in a rat model of N-methylnitrosourea-induced colon carcinogenesis. It also reduces ear edema in a mouse model of inflammation induced by phorbol 12-myristate 13-acetate.

allo-DL-Threonine is a racemic mixture of the D and L isomers of the polar essential amino acid threonine.

SUN-5555 is a penem --- a type of unsaturated β-lactam with a sulfur atom in the five-membered ring. SUN-5555 belongs to the penem group of antibiotics prescribed for oral usage. Enterobacteriaceae bacterial infections with cephalosporin resistance are susceptible to faropenem. Faropenem could be an effective antibiotic to treat urinary tract infections caused by extended-spectrum beta-lactamases (ESBL) producing bacteria.

Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma.

5-trans-Prostaglandin E2 accelerates fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator. It also inhibits platelet aggregation in human PRP.

Algestone is a synthetic progestational dihydroxy derivative of Progesterone. The acetonide group possesses anti-inflammatory properties.

Asukamycin is polyketide isolated from the S. nodosus subspecies asukaensis that demonstrates a broad range of antibiotic functions. It has been shown to inhibit growth of various tumor cell lines by activating caspases 8 and 3.

AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding rats. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.

(R)-AM1241 acts as an agonist at human CB2 receptors but an inverse agonist at rat and mouse CB2 receptors. Similar to the racemate AM1241, (R)-AM1241 produces antinociception to thermal pain but not mechanical pain in rats. The pain-reducing effect of (R)-AM1241 is blocked by the CB2-specific inhibitor SR 144528 but not by either the CB1-selective inhibitor rimonabant or the opioid receptor blocker naloxone.

(S)-AM1241 binds to cannabinoid (CB) receptors and is selective for CB2 over CB1. (S)-1241 acts as an agonist at human, rat, and mouse CB2 receptors but shows greater activity at human CB2 than at rat and mouse CB2 receptors. Similar to the racemate AM1241, (S)-AM1241 produces antinociception to thermal pain but not mechanical pain in rats. The pain-reducing effect of (S)-AM1241 is blocked by the CB2-specific inhibitor SR 144528 but not by either the CB1-selective inhibitor rimonabant or the opioid receptor blocker naloxone

AM-211 sodium is a novel and potent antagonist of the prostaglandin D2 receptor type 2. AM-211 is active in animal models of allergic inflammation. AM211 has high affinity for human, mouse, rat, and guinea pig DP2 and it shows selectivity over other prostanoid receptors and enzymes. AM211 exhibits good oral bioavailability in rats and dogs and dose-dependently inhibits 13,14-dihydro-15-keto-PGD(2)-induced leukocytosis in a guinea pig pharmacodynamic assay.

Mafenide acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.

Ambenonium chloride is a quaternary ammonium compound that inhibits cholinesterase activity with actions similar to those of Neostigmine but of longer duration. Ambenonium is used in the treatment of myasthenia gravis --- a chronic autoimmune neuromuscular disease that causes skeletal muscle weakness.

Amlodipine maleate is a long-acting dihydropyridine calcium channel blocker effective in the treatment of angina pectoris and hypertension.

Phthalimidoamlodipine is an impurity of Amlodipine --- a medication used to lower blood pressure and prevent chest pain.

(R)-Amlodipine is the R isomer of Amlodipine --- a medication used to lower blood pressure and prevent chest pain.

Amoxydramine is a metabolite of Diphenhydramine in humans.

S-(3-Carboxypropyl)-L-cysteine is a thioether derivative of L-cysteine.

Amoxicillin open ring dimer is an impurity of Amoxicillin --- a β-lactam family antibiotic that is commonly used in conjunction with clavulanic acid to the treat bacterial infections.

Augmentin is a 4:1 mixture of Amoxicillin to Clavulanate which serves as a broad-spectrum antibiotic that is effective against resistant pathogens. It maintains therapeutically useful concentrations of plasma Amoxicillin for longer periods after dosing.

(R,S)-AMPA is a glutamate agonist and an Ibotenic Acid homolog . The compound is the defining agonist for the AMPA subtype of glutamate receptors. It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

(S)-AMPA is an active isomer of (RS)-AMPA and selective AMPA agonist.

(R)-AMPA is an inactive isomer of (RS)-AMPA (MedKoo Cat# 573831).

Ampicilloic acid is a metabolite and impurity of the semi-synthetic antibiotic Ampicillin.

Ampicillin Trimer Trisodium Salt is an impurity of Ampicillin that can be used to detect compounds or impurities related to ampicillin in bulk drug.

Ampicillin EP Impurity E is an impurity of Ampicillin --- an antibiotic used to prevent and treat a number of bacterial infections such as respiratory tract infections, urinary tract infections, meningitis, salmonella infections, and endocarditis. Ampicillin EP Impurity E can be used to detect compounds or impurities related to ampicillin in bulk drug.

Migalastat is a potent inhibitor of glycolipid biosynthesis.

Ipidacrine is a ring-constricted derivative of tacrine (Cognex) and a reversible acetylcholinesterase inhibitor used in memory disorders. Ipidacrine directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.

Amisulpride, (R)-, is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.

Azoxystrobin is a strobilurin fungicide that inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1.

N-Methyl amisulpride is an impurity of Amisulpride.

Amitriptyline N-glucuronide is a tricyclic antidepressant with anticholinergic and sedative properties.

Sulfamidopyrine sodium is an impurity of Dipyrone --- a non-steroidal anti-inflammatory drug NSAID) that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance.

Amidephrine is an adrenergic agent.

Aminacrine hydrochloride monohydrate is a highly fluorescent anti-infective dye used as a topical antiseptic and mutagen due to its interaction with DNA. It is also used as an intracellular pH indicator.

Zolamide may be used to prevent and reduce the symptoms of altitude sickness.

ATMP, or aminotris(methylenephosphonic acid), is a phosphonic acid with chelating properties. It is an antiscalant.

Aminohippurate sodium is the glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.

Aminocarnitine is an inhibitor of fatty acid oxidation that acts as a hypoglycemic and antiketogenic compound. It alters lipidic metabolism by inhibiting carnitine acetyltransferase (CAT) and carnitine palmitoyltransferase (CPT).

Benzhydrylamine is a biochemical that may be used in grafting and peptide synthesis.

2-Aminofluorene is a biochemical.

Benfuracarb is a benzofuranyl methylcarbamate based insecticide used to control aphids, springtails and other pests usually on beet crops.

(D)-Aminoglutethimide is a nonsteroidal aromatase inhibitors. Aminoglutethimide is used to decrease the production of sex hormones (estrogen in women or testosterone in men) and suppress the growth of tumors that need sex hormones to grow.

(S)-Aminoglutethimide is an anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Aminoglutethimide is used to decrease the production of sex hormones (estrogen in women or testosterone in men) and suppress the growth of tumors that need sex hormones to grow.

(R)-Aminoglutethimide tartrate is an anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Aminoglutethimide is used to decrease the production of sex hormones (estrogen in women or testosterone in men) and suppress the growth of tumors that need sex hormones to grow.

Aminomethyltrioxsalen hydrochloride is a psoralen compound DNA intercalator used to inactivate DNA and RNA viruses, including HIV-1, by nucleic acid cross-linking followed by UV irradiation.

Aminomethyltrioxsalen is a psoralen compound DNA intercalator used to inactivate DNA and RNA viruses, including HIV-1, by nucleic acid cross-linking followed by UV irradiation.

Pasiniazid is a biochemical used in the treatment of tuberculosis

L-2-Aminosuberic acid is a biochemical.

Aminopyrazine carboxamide is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties.

Aminopyralid is a selective herbicide used for control of broadleaf weeds, especially thistles and clovers. It is in the picolinic acid family of herbicides, which also includes clopyralid, picloram, triclopyr, and several less common herbicides.

Adrenochrome Monoaminoguanidine Mesilate is a chemical compound produced by the oxidation of adrenaline (epinephrine). The derivative carbazochrome is a hemostatic medication.

Mevalonolactone is a chemical that can be used in the preparation of a vitamin E.

Afobazole is a multi-targeted anxiolytic drug with neuroprotective activities. It binds to the sigma-1, melatonin MT1, and MT3 receptors, as well as monoamine oxidase A (MAO-A, Kis = 5.9, 160, 0.97, and 3.6 µM, respectively, in a radioligand binding assay). Afobazole (5 mg/kg) decreases the latency to enter, as well as increases the number of entries into and percentage of time spent in, the open arms of the elevated plus maze, indicating anxiolytic-like activity in passive stress-coping BALB/c, but not active stress-coping C57BL/6, mice. It decreases stroke volume and neuronal and oligodendroglial cell death in the brain in a rat model of ischemia induced by middle cerebral artery occlusion (MCAO) when administered at doses of 0.3 and 3 mg/kg.

Oxolamine citrate is a antiinflammatory drug used as a cough suppressant.

Repaglinide, (-)-, is a Repaglinide impurity where only the R-enantiomer showed weak hypoglycemic activity.

D-Kynurenine is an antagonist of hydroxycarboxylic acid receptor 3 HCA3/GPR109B and a metabolite of D-tryptophan. It increases levels of intracellular calcium and decreases forskolin-stimulated production of cAMP in CHO cells expressing human HCA3/GPR109B. D-Kynurenine increases expression of vimentin and decreases expression of E-cadherin in 95D lung cancer cells. It has been used as a substrate in fluorometric assays for D-amino acid oxidase activity.

Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor Dasatinib. It is also a potential impurity in commercial preparations of dasatinib.

Bacopaside II is a triterpene glycoside found in B. monnieri that has neuroprotective, anti-angiogenic, and anticancer activities. Bacopaside II decreases hydrogen peroxide-induced intracellular reactive oxygen species (ROS) production and cell death in N2a neuroblastoma cells. Bacopaside II decreases migration and tube formation in 2H11 and 3B11 cells, as well as human umbilical vein endothelial cells (HUVECs) when used at concentrations greater than 15 μM. Bacopaside II inhibits the growth of MDA-MB-231, SHG-44, HCT8, A549, and PC3M cancer cells (IC50s = 32.4, 36.9, 40.3, 44.4, and 45.4 μM, respectively).

CAY10735 is an anticancer compound that inhibits proliferation of melanoma, breast, pancreatic, and lung cancer cell lines by inhibiting the epithelial-to-mesenchymal transition (EMT).

4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity. It is cytotoxic to A2780 ovarian cancer cells but not to carboplatin-resistant A2780 cells. It is selective for A2780 cells over non-cancerous ARPE19 cells. 4-oxo-27-TBDMS Withaferin A induces DNA fragmentation in A2780 cells.

Astringin is a phenolic stilbene glucoside that has antioxidant and antineoplastic activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and inhibits cupric ion-induced lipid peroxidation of human LDL. Astringin inhibits development of preneoplastic lesions induced by 7,12-dimethylbenz(a)anthracene (DMBA) in mouse mammary glands.

4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity. It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells and is 4.4-fold selective for A2780 cells over non-cancerous ARPE19 cells.

Oxychlororaphine is a phenazine microbial metabolite that has been found in a variety of bacteria and has anticancer, antibacterial, and antifungal activities. It is cytotoxic to A549, HeLa, and SW480 cancer cells. Oxychlororaphine halts the cell cycle at the G1 phase and induces apoptosis in A549 cells. It is active against Streptomyces bacteria and T. mentagrophytes, E. floccosum, C. albicans, M. audouini, and B. dermatitidis fungi.

(+)-Pinoresinol is a lignan that diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It is an inhibitor of α-glucosidase and maltase. (+)-Pinoresinol scavenges ABTS but not 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals in cell-free assays. It is cytotoxic to A549, HepG2, and MCF-7, but not U251 and Bcap-37 cells. (+)-Pinoresinol prevents cell death induced by glutamate in HT22 cells and inhibits LPS-induced nitric oxide production in RAW 264.7 cells.

CAY10736 is an anticancer compound. It inhibits proliferation of melanoma and breast, pancreatic, and lung cancer cell lines. CAY10736 inhibits migration and epithelial-to-mesenchymal transition (EMT) of A375 and B16/F10 melanoma cells in vitro in a concentration-dependent manner. It reduces the viability of spheroid A375 and B16/F10 cells and increases the production of reactive oxygen species (ROS).

Thymohydroquinonee is a quinone that has been found in N. sativa seeds and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radicals and inhibits growth of A2780, OVCAR-8, CIS-A2780 ovarian cancer cells, and immortalized human ovarian epithelial cells. It is also active against P. falciparum in vitro.

4β-Hydroxywithanolide E is a withanolide steroidal lactone that has anti-inflammatory and anticancer activities. It inhibits LPS-induced nitric oxide (NO) production and TNF-α-induced NF-κB activity. 4β-Hydroxywithanolide E inhibits LPS-induced increases in inducible nitric oxide synthase (iNOS) and COX-2 levels and Akt and STAT1 phosphorylation. It inhibits Wnt signaling in HCT116 and SW480 colorectal cancer cells (IC50s = 1.85 and 2.67 μM, respectively).3 4β-Hydroxywithanolide E inhibits the proliferation of HCT116, SW480, HT-29, and LoVo cells.

5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.

2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2. It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1) and reduces prostaglandin E2 (PGE2) production in HeLa, A549, and HCA-7 cells. It inhibits proliferation of drug-sensitive RPMI8226 and multidrug-resistant 8226/Dox40 multiple myeloma cells, as well as increases the rate of apoptosis when used at concentrations of 20 and 30 μM. 2,5-dimethyl Celecoxib reduces the expression of survivin, cyclin A, cyclin B, MEK1, and MEK2 in 8226/Dox40 cells. The antiproliferative effect of 2,5-dimethyl celecoxib is independent of mPGES-1 inhibition.

α-methyl Serotonin (maleate) is an agonist of serotonin (5-HT) receptors. It binds selectively to 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1D receptors over 5-HT1E receptors. It is also selective for 5-HT2B and 5-HT2C receptors over 5-HT2A receptors. α-methyl Serotonin potentiates motor neuron depolarizations induced by NMDA in the presence of the NMDA receptor antagonist memantine. It also increases dopamine release in a dose-dependent manner. α-methyl Serotonin increases systolic blood pressure and transiently increases heart rate.

N-desmethyl Ivabradine (hydrochloride) is an active metabolite of ivabradine. Ivabradine is metabolized by the cytochrome P450 (CYP) isoform CYP3A4.