Cat. No. | Product name | CAS No. |
DCC2449 |
Gw780056x
Selective cyclin dependent kinase inhibitor; Inhibitor of Yes1 kinase; Inhibitor of binding or entry into cells for Lassa Virus |
1093294-48-4 |
DCC2450 |
gw7845
Selective agonist of peroxisome proliferator-activated receptor-γ (PPARγ) |
196809-22-0 |
DCC2451 |
Gw807982x
Potent and selective inhibitor of glycogen synthase kinase 3 (GSK3) |
|
DCC2452 |
Gw809897x
Novel and potent inhibitor of VEGFR2 tyrosine kinase, non-selectivey inhibiting AURKA and AURKB |
|
DCC2453 |
Gw827106x
Potent GSK-3 inhibitor, highly selective over CDK-2 |
681432-07-5 |
DCC2454 |
Gw833373x
Novel Inhibitor of GSK3beta |
681432-85-9 |
DCC2455 |
Gw837016x
Novel inhibitor of mitosis and cytokinesis in T. brucei which causes human African trypanosomiasis (HAT) |
833473-68-0 |
DCC2456 |
Gw844520
Novel potent and selective inhibitor of the cytochrome bc1 complex of mitochondrial electron transport in P. falciparum |
137735-25-2 |
DCC2457 |
gw853606
Novel polo-like kinase (PLK1) inhibitor |
660869-54-5 |
DCC2458 |
Gw856804x
Novel NAD+-competitive Sirt2 inhibitor |
|
DCC2459 |
Gwl-78
Novel modulator of NF-Y transcription, inhibiting the binding of NF-Y to DNA, blocking cellular proliferation and cell cycle progression, interacting with a variety of CCAAT-containing promoters leading to p53-independent cell cycle arrest |
|
DCC2460 |
Gx-395
Novel inhibitor of Nav1.7 |
1235403-87-8 |
DCC2461 |
Gx-585
Novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2 |
|
DCC2462 |
Gx-629
GX-936 analog, antagonist of voltage-gated sodium 1.7 (Nav1.7) channels |
|
DCC2463 |
Gyki-53655
AMPA antagonist |
143692-18-6 |
DCC2464 |
Gyramide A
Novel bacterial DNA gyrase inhibitor, exhibiting antimicrobial activity and inhibiting bacterial cell division |
913509-94-1 |
DCC2465 |
H-0104 Dihydrochloride
Novel Rho-associated coiled coil-formed protein kinase (ROCK) inhibitor, exerting strong intraocular pressure (IOP)-lowering effects into the eyes of monkeys |
913636-88-1 |
DCC2466 |
H-0106 Dihydrochloride
Novel Rho-associated coiled coil-formed protein kinase (ROCK) inhibitor, exerting strong intraocular pressure (IOP)-lowering effects into the eyes of monkeys |
1011465-90-9 |
DCC2467 |
h1-agonist-39
Novel full H1 agonist |
162049-83-4 |
DCC2468 |
H2-003
Novel class of selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor |
1060438-30-3 |
DCC2469 |
H2-005
Novel class of selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor |
1060478-12-7 |
DCC2470 |
H2a-4t
Novel water-soluble and biocompatible small-molecule near-infrared II (NIR-II) fluorescent dye |
|
DCC2471 |
h2lassbio-1064
Inhibitor of acetic acid-induced writhing response |
125741-50-6 |
DCC2472 |
H-4073
Novel inhibitor of STAT3 activation, inhibiting head and neck cancer cell proliferation in a dose dependent manner |
|
DCC2473 |
H77-77
Inhibitor of monoamine oxidase (MAO) |
21618-99-5 |
DCC2474 |
Ha Protein Inhibitor 1
Novel hemagglutinin (HA) protein inhibitor, inhibiting entry and replication of diverse influenza viruses via the HA protein, showing potent antiviral activity against diverse H1N1, H5N1, and H3N2 influenza viruses encoding HA proteins from both groups 1 |
346715-10-4 |
DCC2475 |
Halauxifen
Herbicide, being used for the control of broad-leaved weeds in cereals and oilseed rape |
943832-60-8 |
DCC2476 |
Halobetasol
Topical corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities, inducing phospholipase A2 inhibitory proteins, activating gene expression of anti-inflammatory proteins mediated via the corticosteroid receptor response element |
98651-66-2 |
DCC2477 |
Halofantrine Hydrochloride
Antimalarial, binding to plasmpesin, a haemoglobin degrading enzyme unique to the malarial parasites |
36167-63-2 |
DCC2478 |
Halofenate
Selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) modulator with antilipidemic activity |
26718-25-2 |
DCC2479 |
Haloprotac2
Novel HaloPROTAC degrader, inducing degradation of HaloTag fusion proteins |
1799506-06-1 |
DCC2480 |
Haloquinone
Novel Wnt inhibitor, blocking Wnt signaling downstream of beta-Catenin |
80902-01-8 |
DCC2481 |
Haploscleridamine
Novel inhibitor of cathepsin K (CatK) |
|
DCC2482 |
Haptamide B
Novel selective inhibitor of Hap2/3/4/5p mediated transcription in vivo. |
546124-87-2 |
DCC2483 |
Harringtonolide
Natural antiproliferative, antifungal, antitumor agent, suppressing the epithelial-mesenchymal transition (EMT) process and inhibiting activation of the FAK/Src/STAT3 signaling pathway in A375 cells, targeting RACK1 to suppress cancer cell migration |
64761-48-4 |
DCC2484 |
hat Inhibitor C107
Novel p300/CBP HAT inhibitor |
1417741-58-2 |
DCC2485 |
Hatric
Precursor for HATRIC-based ligand receptor capture (HATRIC-LRC) |
|
DCC2486 |
Hbf-0079
Hepatocellular carcinoma (HCC)-selective cytotoxin, suppressing AKT anti-apoptotic signaling |
315702-93-3 |
DCC2487 |
Hc102a
Novel Inhibitor of Mycobacterium tuberculosis DosRST signaling and persistence |
91216-38-5 |
DCC2488 |
Hc103a
Novel Inhibitor of Mycobacterium tuberculosis DosRST signaling and persistence |
312595-37-2 |
DCC2489 |
Hc104a
Novel inhibitor of DosRST, inhibiting DosR DNA binding in a dose-dependent manner by directly targeting DosR |
|
DCC2490 |
Hc106a
Novel inhibitor of DosRST, inhibiting Mtb survival during hypoxia-induced NRP, directly targeting the sensor kinase heme, via a mechanism that is distinct from the oxidation and alkylation of heme previously observed with artemisinin (HC101A) |
|
DCC2491 |
Hca Xii-in-2c
Novel inhibitor of human carbonic anhydrase XII (hCA-XII), demonstrating significant antiproliferative activity against hypoxic tumor cell lines |
|
DCC2492 |
Hca-ix/xii-in-4m
Novel selective dual carbonic anhydrase IX and XII inhibitor |
|
DCC2493 |
Hci-2184
Novel Nek2 inhibitor, successfully mitigating drug resistance in bortezomib-resistant multiple myeloma; Potent AXL kinase inhibitor |
1341200-61-0 |
DCC2494 |
Hcov-in-8n
Novel inhibitor of human coronavirus 229E (hCoV 229E) replication with an EC50 value of 5.5 µM |
|
DCC2495 |
HCT1026
Selective modulator of amyloid-beta peptide degradation, regulating Abeta levels. |
158836-71-6 |
DCC2496 |
Hct-13
Novel copper-dependent cytotoxic agent, being highly potent against a panel of pancreatic, small cell lung carcinoma, prostate cancer, and leukemia models, with IC50 values in the low-to-mid nanomolar range |
|
DCC2497 |
Hcv Gt2a Inhibitor 5m
Antiviral agent against HCV genotype 2a JFH-1 infected in human Huh7.5.1 cells |
|
DCC2498 |
Hcv-in-5
Novel Inhibitor of Hepatitis C Virus |
491586-35-7 |
DCC2499 |
Hd-800
High affinity and selective colchicine site tubuline inhibitor amenable to radiolabel with C-11, a positron emitting isotope |
|
DCC2500 |
Hdac6 Degrader 14a
Novel PROTAC HDAC6 degrader, efficiently and selectively decreased HDAC6 levels in several cell lines, including activated THP-1 cells |
|
DCC2501 |
Hdac6 Degrader Np8
Novel potent and selective PROTAC degrader of HDAC6 protein |
|
DCC2502 |
Hdac6 Inhibitor 6h
Novel hHDAC6 inhibitor, having low inhibitory potency over hHDAC1 and hHDAC8, as potential pharmacological tools for idiopathic pulmonary fibrosis (IPF) treatment |
|
DCC2503 |
Hdac6 Inhibitor Xp5
Novel potent HDAC6 inhibitor with an IC 50 of 31 nM and excellent HDAC6 selectivity (SI = 338 for HDAC6 over HDAC3), displaying high antiproliferative activity against various cancer cell lines including the HDACi-resistant YCC3/7 gastric cancer cells (IC |
|
DCC2504 |
Hdac6-in-10c
Novel HDAC6 isoform-selective inhibitor, increasing the acetylation level of α-tubulin with little effect on the acetylation of histone H3, inducing apoptosis in HL-60 cell by activating caspase 3 |
|
DCC2505 |
Hdac6-in-3f
Potent and selective HDAC6 inhibitor |
|
DCC2506 |
Hdac6-in-4b
Potent and selective HDAC6 inhibitor |
|
DCC2507 |
Hdac6-in-w5
Novel highly potent and selective HDAC6 inhibitor with an IC 50 of 2.54 nM and being more than 290- to 3300-fold selective over other HDAC isoforms |
|
DCC2508 |
Hdac8 Protac
First-in-class proteolysis targeting chimera (PROTAC) for selective degradation of histone deacetylase 8 (HDAC8) |
|
DCC2509 |
Hdac8-in-8b
Novel Selective Histone Deacetylase 8 (HDAC8) Inhibitor with Anti-Neuroblastoma Activity |
|
DCC2510 |
Hdac-in-6
Novel HDAC inhibitor, targeting HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, and HDAC9 |
1026295-98-6 |
DCC2511 |
Hdac-in-h13
Novel Histone deacetylase (HDAC) inhibotor, displays potent inhibitory activity towards human HDACs and several cancer cells lines |
|
DCC2512 |
Hdl376
Featured
HDL376 is a scavenger receptor class B type I (SR-BI) inhibitor. HDL376 directly inhibits SR-BI-mediated lipid transport in cells and in liposomes reconstituted with purified SR-BI (IC50 = 0.22 μM). HDL376 can be used for the research of atherosclerotic coronary artery disease. |
147751-31-3 |
DCC2513 |
Hdp-mimic C4
Potent antifungal agent, hosting defense peptide mimic through a membrane-active mechanism |
|
DCC2514 |
Hds029
Potent inhibitor of the ErbB receptor family (IC50 values are 0.3, 0.5 and 1.1 nM for ErbB1 (EGFR), ErbB4 and ErbB2 respectively) |
881001-19-0 |
DCC2515 |
Helenalin Acetate
Anti-inflammatory and anti-cancer agent, disrupting the cooperation of CCAAT-box/enhancer-binding protein beta (C/EBPß) and co-activator p300 |
10180-86-6 |
DCC2516 |
Helenalin Methacrylate
Natural anti-inflammatory and anti-cancer agent |
68798-43-6 |
DCC2517 |
Helioxanthin
Inhibitor of interleukin-1β-induced MIP-1β production |
18920-47-3 |
DCC2518 |
Hemiasterlin
Cytotoxic peptide, inducing mitotic arrest and abnormal spindle formation |
157207-90-4 |
DCC2519 |
Hemigossypol
The biosynthetic precursor of gossypol |
40817-07-0 |
DCC2520 |
Hemisurfen
Heparan sulfate antagonist |
46696-26-8 |
DCC2521 |
Heparin Disaccharide I-s Sodium Salt
Heparin derivative for treatment of thrombotic diseases |
136098-10-7 |
DCC2522 |
Hepcidin
Master regulator of iron homeostasis, contributing to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss |
1356390-47-0 |
DCC2523 |
Hepta-histidine
Novel inhibitor of Tau aggregation against Tau-related neurodegenerative diseases including Alzheimer's disease (AD) |
64134-31-2 |
DCC2524 |
Het-dpd-13a
Novel LsrK inhibitor (ID 50 119 μM) agaist antimicrobial resistance (AMR) |
|
DCC2525 |
Heterotaxin
Novel TGF-β Signaling Inhibitor |
886862-25-5 |
DCC2526 |
Hetrombopag Olamine
Novel orally bioavailable, non-peptide thrombopoietin (TPO) receptor agonist |
1257792-42-9 |
DCC2527 |
Hexafluoro
Novel inhibitor of the phosphorylation of DRP1, stimulating a phenotype suggestive of respiration through mitochondrial normalization and demonstrating activity in Vemurafenib-resistant melanoma in vivo |
128481-73-2 |
DCC2528 |
Hexim1 Inducer 4a1
Novel potent inducer of hexamethylene bis-acetamide inducible protein 1 (HEXIM1) |
|
DCC2529 |
Hexyl-acrdim
Potent inducer of oxidative stress as well as cell cycle arrest in the S-phase, significantly decreasing intracellular ATP level |
|
DCC2530 |
Hfi-142
Insulin-regulated aminopeptidase (IRAP) inhibitor, mprovin memory in control and memory-deficient mice models |
332164-34-8 |
DCC2531 |
Hg-7-85-01
Novel type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases |
1258391-13-7 |
DCC2532 |
Hgh Fragment 177-191 (tfa Salt)
Fragment 177-191 of human growth hormone, regulating fat metabolism but without the adverse effects on blood sugar or growth, stimulating lipolysis (the breakdown or destruction of fat) and inhibiting lipogenesis (the transformation of nonfat food materia |
66004-58-8 |
DCC2533 |
Hhs-465
Novel sulfur-triazole exchange (SuTEx) covalent probe with ~5-fold enhanced chemoselectivity for tyrosines over other nucleophilic amino acids |
|
DCC2534 |
Clomethiazole Edisylate
Positive allosteric modulator at the barbiturate/picrotoxin site of the GABAA receptor |
1867-58-9 |
DCC2535 |
Hi-207
Non-nucleoside reverse transcriptase inhibitor |
244268-79-9 |
DCC2536 |
Hi-253
Potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus (HIV) |
|
DCC2537 |
Hi-346
Potent inhibitor of multidrug-resistant human immunodeficiency virus-1 (HIV-1) |
149486-68-0 |
DCC2538 |
Hiapp(22-27)
Hexapeptide sequences of hIAPP, being sufficient for the formation of beta-sheet-containing amyloid fibrils and coiling around each other in a typical amyloid fibril morphology |
121341-41-1 |
DCC2539 |
Hiapp(23-27)
Pentapeptide sequences of hIAPP, being sufficient for the formation of beta-sheet-containing amyloid fibrils and self-assemble laterally into unusually broad ribbons |
|
DCC2540 |
Hie-124
CNS active anticonvulsant and ultra-short acting hypnotic |
805326-00-5 |
DCC2541 |
Hif-1alpha Inhibitor-1
Novel HIF-1alpha inhibitor |
1000025-14-8 |
DCC2542 |
Hif-1alpha-p300 Ppi Inhibitor-3
Novel HIF-1alpha-p300 Protein Protein Interaction inhibitor |
|
DCC2543 |
Hif-hydroxylase Modulator
Novel hypoxia inducible factor hydroxylase modulator |
909010-67-9 |
DCC2544 |
Hif-hydroxylase Modulator-ii
Novel hypoxia inducible factor hydroxylase modulator |
952397-50-1 |
DCC2545 |
Hif-in-33
Novel HIF Pathway Inhibitor |
1085450-53-8 |
DCC2546 |
Himbacine
Natural muscarinic receptor antagonist |
6879-74-9 |
DCC2547 |
Hipk1/2-in-a64
Novel Potent Inhibitor of HIPK1/HIPK2 Kinase |
|
DCC2548 |
Hippeastrine Hydrobromide
Natural alkaloid, demonstrating significant cytotoxicity against a panel of human and murine tumor cell lines |
22352-41-6 |
DCC2549 |
Histidine-proline
Allosteric inhibitor of ATP phosphoribosyltransferase (ATPPRT), binding to the ATPPRT:ATP complex via a two-step binding mechanism, inhibiting ATPPRT competitively and likely uncompetitively, respectively, against PRPP and ATP |
20930-58-9 |
DCC2550 |
Histidyl-histidine
Novel enhancer of catalytic efficiency of neurolysin |
306-14-9 |
DCC2551 |
Histidyltyrosine
Novel enhancer of catalytic efficiency of neurolysin |
35979-00-1 |
DCC2552 |
Hiv-1 In Photoprobe
Novel photoaffinity-labeled probe for full-length human immunodeficiency virus-1 integrase (HIV-1 IN) |
|
DCC2553 |
Hiv-1 Inhibitor 9d
Novel highly potent HIV-1 inhibitor with broad-spectrum activity (EC50 = 2.0-57 nM) against resistant strains, exhibiting good solubility and safety profiles and a good PK profile with an oral bioavailability of 59% in rats |
|
DCC2554 |
hjc0122
AMPA Receptor Positive Allosteric Modulator |
1453096-68-8 |
DCC2555 |
Hjc0123
Novel orally bioavailable STAT3 inhibitor |
1430420-02-2 |
DCC2556 |
Hjc0149
Novel potent orally bioavailable inhibitor of signal transducer and activator of transcription 3 (STAT3) |
1430330-65-6 |
DCC2557 |
Hjc05100
Novel apigenin analogue, suppressing pancreatic stellate cell proliferation |
1612891-85-6 |
DCC2558 |
Hk Inhibitor 2
Novel inhibitor of YycG histidine kinase (HK), showing potent antibiofim activity against Staphylococcus epidermidis |
352683-04-6 |
DCC2559 |
Hk2 Modulator-1
Novel allosteric hexokinase 2 (HK2) modulator, selectively detaching HK2 from the mitochondria |
|
DCC2560 |
hl010183
Novel Metformin Derivative; Inhibitor of Proliferation and Invasion of Triple-Negative Breast Cancer Cells |
1125365-14-1 |
DCC2561 |
Hl-3-68
Novel SARS-CoV-2 Main Protease (Mpro) inhibitor, binding to Subsites S1 and S2 (K d =0.69 µM) |
|
DCC2562 |
hla20a
Selective Acetylcholinesterase Inhibitor |
1162140-23-9 |
DCC2563 |
Hlb-0532247
Novel phosphoramidate prodrug of ddhCTP, effectively reducing titers of Zika and West Nile viruses in cell culture with minimal nonspecific toxicity to host cells |
|
DCC2564 |
Hlcl-61
First-in-class inhibitor of protein arginine methyltransferase 5 (PRMT5) |
586395-74-6 |
DCC2565 |
Hlö-7 Dimesylate
Novel Nerve Agent Reactivator |
|
DCC2566 |
Hm-50316
Potent and highly selective FABP4 inhibitor |
1310361-52-4 |
DCC2567 |
Hm90822
Novel antagonist to the inhibitors of apoptosis (IAPs), potentiating cell death in EGFR-overexpressing non-small-cell lung cancer cells |
|
DCC2568 |
Hmao-b Inhibitor 5
Novel highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability profile and neuroprotective action (IC 50 = 42 nM; SI > 2375) |
|
DCC2569 |
Hmbpp Triammonium Salt
Potent stimulator of gamma delta T cells |
443892-56-6 |
DCC2570 |
Hmi-1a3
Protein kinase C partial agonist, targeting the C1 domain, inhibiting cell proliferation, decreasing cell viability and inducing an apoptotic response |
|
DCC2571 |
Hmk-32
Irriversible inhibitor of GSK3 |
|
DCC2572 |
Hm-mc4-ppea
Potent inhibitor of nicotinamide phosphoribosyltransferase (Nampt) |
|
DCC2573 |
Hmr1031
Potent and specific integrin α4ß1 or very late antigen 4 (VLA-4) receptor antagonist, binding to vascular cell adhesion molecule-1 (VCAM-1) and fibronectin |
479203-71-9 |
DCC2574 |
Hmr1426
Novel food intake-reducing agent |
262376-75-0 |
DCC2575 |
Hmr-1566
Potent and selective I ks channel blocker |
223749-45-9 |
DCC2576 |
Hmref-s-neu5ac
Novel sialidase-activatable fluorescence probe with improved stability for the sensitive detection of sialidase |
|
DCC2577 |
Hmref-ßglcnac
Novel Hexosaminidase-Targeting Fluorescence Probe for Visualizing Human Colorectal Cancer. |
|
DCC2578 |
Hms-i1
Novel chemical probe for heterochromatin formation and function, disrupting of heterochromatin-mediated transcriptional gene silencing |
702636-92-8 |
DCC2579 |
Hms-i2
Novel chemical probe for heterochromatin formation and function, disrupting of heterochromatin-mediated transcriptional gene silencing |
690626-60-9 |
DCC2580 |
Hmsir-tubulin
Novel Blinking Fluorescent Probe for Tubulin Nanoscopy in Living and Fixed Cells |
|
DCC2581 |
Hn-cbl
Novel selective inhibitor of the lymphocytic leukemia (LL) cell survival , Selectively Enhancing the Killing Effect through STAT3 Binding on Lymphocytic Leukemia Cells In Vitro and In Vivo |
|
DCC2582 |
Hnpc-a3066
Novel strobilurin acaricide, exhibiting larvicidal and ovicidal activities against various acarids |
|
DCC2583 |
Hocpca
Highly potent and selective ligand for the GHB binding sites, binding with 27 times better affinity than GHB itself and acrossing the blood brain barrier in vitro and in vivo |
867178-11-8 |
DCC2584 |
Hoechst-3325
Fluorescent indicator of apoptosis, binding the minor groove of DNA at A and T rich regions |
23491-44-3 |
DCC2585 |
Hoi-07
Novel specific Aurora B inhibitor |
1606160-40-0 |
DCC2586 |
Holomycin
Antibiotic |
488-04-0 |
DCC2587 |
Holothurin A
Natural inhibitor of dietary fat absorption and showing strong anti-obesity activity |
38-26-6 |
DCC2588 |
Homochlorcyclizine Dihydrochloride
Histamine H1 receptor antagonist |
1982-36-1 |
DCC2589 |
Homovanillyl Sinapate
Novel c-Met inhibitor, markedly reducing tumor growth, showing excellent pharmacodynamics, and suppressing cell proliferation and microvessel density in an orthotopic model of triple negative breast cancer |
|
DCC2590 |
Hpta-1
Novel highly selective switch-on fluorescence sensor, targeting telomeric dimeric G-quadruplex, discriminating the telomeric dimeric G-quadruplex TTA45 against other types of DNA structures accompanied by a drastic enhancement of the emission intensity wi |
|
DCC2591 |
Hpxr-agonist-28
Novel silanol-based human pregnane X receptor (PXR) agonist |
|
DCC2592 |
Hr1405-01
Loxoprofen active metabolite, acting as a safe intravenous NSAID with superior anti-inflammatory and analgesic activities |
83648-76-4 |
DCC2593 |
Hras-1y I-motif Probe-1
Novel Probe of the hras-1Y i-motif , selectively and directly interacting with the hras-1Y i-motif. |
|
DCC2594 |
Hrv-14 Inhibitor 3v
Inhibitor of human rhinoviruses serotype 14 (HRV-14) |
|
DCC2595 |
Hs-438
Novel inhibitor of imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia |
1430720-10-7 |
DCC2596 |
Hs-731
μ-Opioid Receptor Agonist |
547767-45-3 |
DCC2597 |
Hsa-5b
Novel anticancer Gold(III) agent with remarkable cytotoxicity to gastric cancer cells |
|
DCC2598 |
Hsd1237
Novel potent inhibitor of the recombinant FLT3 kinase and its mutant forms, blocking the proliferation of AML cell lines, harboring oncogenic FLT3-ITD mutations with remarkable IC50 values, which were comparable to the approved FLT3 inhibitor quizartinib, |
|
DCC2599 |
Hsgn-94
Novel inhibitor of lipoteichoic acid (LTA) biosynthesis, potently inhibiting S. aureus and E. faecalis growth and biofilm formation |
|
DCC2600 |
Hsk21542
Novel Peripherally-Restricted Kappa Opioid Receptor (KOR) Agonist with Antinociceptive and Antipruritic Effects |
|
DCC2601 |
Hsp27-in-i
Novel inhibitor of heat shock 27 kDa protein (HSP27), significantly inducing AR degradation in GBM cells via the proteasomal pathway, selectively inhibiting AR-overexpressed GBM cell growth with IC 50 values around 5 nM |
|
DCC2602 |
Hsp90-aha1 Inhibitor A16
Novel Hsp90-Aha1 chaperone complex formation inhibitor, enhancing F508del-CFTR channel activity |
4536-70-3 |
DCC2603 |
Hsp90-in-30f
Novel potent inhibitor of heat shock protein 90 (Hsp90), effectively reducing the expression levels of Hsp90 client proteins including Her2, EGFR, Met, Akt, and c-Raf |
|
DCC2604 |
Hsp90-in-89
Novel heat shock protein 90 (Hsp90) inhibitor |
1087140-75-7 |
DCC2605 |
Hsp90-in-s89
Novel heat shock protein 90 (Hsp90), more potent enantiomer |
313379-34-8 |
DCC2606 |
Htl0028016
Novel macrocyclic calcitonin gene-related peptide (CGRP) receptor antagonist |
|
DCC2607 |
Htl0028125
Novel macrocyclic calcitonin gene-related peptide (CGRP) receptor antagonist |
|
DCC2608 |
Htl26119
Novel allosteric antagonist of the glucagon-like peptide-1 receptor (GLP-1R) |
|
DCC2609 |
Htl6641
Novel, potent, selective, and orally efficacious dual antagonist of the orexin receptors |
|
DCC2610 |
hts05737
Novel activator of PC2 |
697229-30-4 |
DCC2611 |
Huhs029
Novel analgesic agent, activating TRPA1 and subsequently desensitizing the channel, exhibiting higher inhibitory activity than resveratrol |
|
DCC2612 |
Human Vitronectin (351-359)
Adhesive peptide (sequence 351-359 mapped on the Human Vitronectin Protein), covalent and selective functionalizing on glass and titanium surfaces, increasng osteoblast attachment and adhesion strength and to promoting osseointegration |
|
DCC2613 |
Hur-ligand-4
Novel human antigen R (HuR) ligand, acting as a HuR-RNA interferer |
|
DCC2614 |
Hy1-pt
Novel CK2-Specific Pt(II) Compound, Reversing Cisplatin-Induced Resistance by Inhibiting Cancer Cell Stemness and Suppressing DNA Damage Repair in Non-small Cell Lung Cancer Treatments |
|
DCC2615 |
Hycanthone Mesylate
Inhibitor of apurinic endonuclease-1 (APE1) by direct protein binding |
23255-93-8 |
DCC2616 |
Hydro-1080
Activable Probe for Noninvasive Hydroxyl Radical Imaging, emitted in 1000-1400 nm after responding to ·OH |
|
DCC2617 |
Hydrocaffeoyl-fasudil 1d
Novel multitarget Fasudil derivative, inducing the NRF2 signature, promoting the expression of the antioxidant response enzymes HO-1 and NQO1, via a KEAP1-dependent mechanism |
|
DCC2618 |
Hydrolapachol
Novel potent and selective inhibitor of Schistosoma mansoni dihydroorotate dehydrogenase (SmDHODH) |
3343-38-2 |
DCC2619 |
Hydroxyellipticine-1a
Novel selective r(CGG)exp probe, improving pre-mRNA splicing defects, inhibiting formation of nuclear inclusions and RANT in a FXTAS cellular model |
109628-38-8 |
DCC2620 |
Hydroxymatairesinol
Natural antioxidant and anti-cancer agent, blocking the MAPK/NF-κB and activating Nrf2/HO-1 |
20268-71-7 |
DCC2621 |
Hydroxytriolein
Novel anticancer agent, inhibiting lung cancer cell proliferation via a PKCa and ERK1/2 dependent mechanism |
|
DCC2622 |
Hymenidin
Natural antagonist of serotonergic receptors and inhibitor of CDK5/p25 and GSK-3ß |
107019-95-4 |
DCC2623 |
Hys-32
Novel analogue of combretastatin A-4, enhancing connexin43 expression |
1528729-98-7 |
DCC2624 |
Hz-ma Hybrid 11b
Novel potent and selective inhibitor of fat mass obesity-associated protein (FTO), being selectively over alkylation repair homologue 5 (ALKBH5), another DNA/RNA demethylase |
|
DCC2625 |
Iag-10
Novel potent and selective inhibitor of human DNA polymerase kappa (hpol κ) |
|
DCC2626 |
Ianthellamide A
Selective kynurenine-3-hydroxylase inhibitor |
1374875-85-0 |
DCC2627 |
Ianthelliformisamine A Tfa Salt
Antibiotic enhancer against resistant Gram-negative bacteria |
1643593-28-5 |
DCC2628 |
Ianthelliformisamine B Tfa Salt
Antibiotic enhancer against resistant Gram-negative bacteria |
1643593-29-6 |
DCC2629 |
Ianthelliformisamine C Tfa Salt
Antibiotic enhancer against resistant Gram-negative bacteria |
1643593-30-9 |
DCC2630 |
Iap-in-1
Novel antagonist of IAP (inhibitor of apoptosis protein) |
1005342-47-1 |
DCC2631 |
Iaxo-101
Novel inhibitor of the cluster of differentiation 14 innate immunity pathway |
1202388-64-4 |
DCC2632 |
Ibe-667
Novel activator of LFA-1-ICAM-1 binding |
|
DCC2633 |
Ibl-302
First-in-class triple-acting PIM/PI3K/mTOR inhibitor, demonstrating single-agent, anti-tumour efficacy in suppression of pAKT, pmTOR and pBAD in the SKBR-3, BT-474 and HCC-1954 HER2+/PIK3CA-mutated cell lines |
|
DCC2634 |
Ibpr001 Hydrochloride
Novel Aurora kinase inhibitor |
1192754-04-3 |
DCC2635 |
Ibpr002
Novel Aurora kinase inhibitor, revealing mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules |
1192754-38-3 |
DCC2636 |
Ibrutinib-bfl
Novel fluorescent irreversible inhibitor of Bruton's tyrosine kinase (BTK) |
|
DCC2637 |
Ibs399024
Novel HDAC6-selective inhibitor |
|
DCC2638 |
Ic2418
MmpL3 inhibitor, being active against drug-resistant Mycobacterium tuberculosis |
1432641-65-0 |
DCC2639 |
ica-27243
Neuronal Kv7 potassium channel activator |
325457-89-3 |
DCC2640 |
Icagen-4
Inhibitor of voltage-gated K(+) (Kv) channels Kv1.3 and Kv1.5 |
|
DCC2641 |
Ical-36
Novel inhibitor of CALP, exhibiting affinity of 22.6 ± 8.0 μM for CALP and no interaction with the NHERF PDZ domains |
|
DCC2642 |
icec0943
Novel selective inhibitor of CDK7 |
|
DCC2643 |
Ici-185282
Potent thromboxane receptor antagonist |
106393-80-0 |
DCC2644 |
Ici-56780
Antimalarial agent, displaying blood schizonticidal activity against P.berghei |
28130-28-1 |
DCC2645 |
Iclaprim
Novel selective bacterial dihydrofolate inhibitor, antibiotic, actively against Gram positive organisms |
192314-93-5 |
DCC2646 |
Icl-ccic-0019
Novel potent and selective inhibitor of choline kinase alpha (CHKA) |
936498-64-5 |
DCC2647 |
Icl-sirt078
Novel highly selective, substrate-competitive SIRT2 inhibitor, displaying a significant neuroprotective effect in a lactacystin-induced model of Parkinsonian neuronal cell death in the N27 cell line |
1060430-64-9 |
DCC2648 |
Icpd62
Novel inhibitor of heat shock protein 90 (Hsp90), demonstrating anticancer activity against colorectal, osteosarcoma and cervical cancer cell lines |