Cat. No. | Product name | CAS No. |
DC73936 |
CASK chemical probe 18
CASK chemical probe 18 is a highly potent and selective CASK inhibitor with IC50 of 22 nM. |
2755241-73-5 |
DC73937 |
CB253
CB253 is a small molecule that selectively binds the hairpin form of r(G4C2)exp, inhibiting mechanisms that drive c9ALS/FTD pathobiology. |
1225169-17-4 |
DC73938 |
CBK034026C
CBK034026C is a small molecule targeting metabolic vulnerabilities caused by N-acetyltransferase 2 (NAT2) activity, exhibits specific toxicity towards colorectal cancer (CRC) cells with high NAT2 activity. |
|
DC73939 |
CBLC000
CBLC000 (CBL0100) is a small molecule histone chaperone FACT inhibitor, activates p53 and inhibits NF-κB with EC50 of 0.06 and 0.03 uM in cell-based p53 and NF-κB reporter assays, respecitvely. |
1197996-83-0 |
DC73940 |
CC-410
CC-410 (CC410) is a potent, specific inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 1.6 uM (human NNMT). |
636564-27-7 |
DC73941 |
CHD1Li 11
CHD1Li 11 (CHD1L inhibitor 11) is a small molecule inhibitor of chromodomain helicase DNA-binding protein 1 like (CHD1L) with IC50 of 4.57 uM. |
1015582-93-0 |
DC73942 |
CIB-3b
CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells. |
124811-87-6 |
DC73943 |
Cimlanod
Cimlanod is a second-generation nitroxyl (HNO) donor.. |
1620330-72-4 |
DC73944 |
CK147
CK147 (CK-147) is a potent CD4 down-modulator with IC50 of 63 nM, inhibits Sec61-dependent cotranslational translocation of huCD4 in vitro. |
1883356-12-4 |
DC73945 |
CKi-4
Creatine kinase inhibitor CKi-4 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.3 uM, depletes creatine phosphagen energetics in cells. |
2768295-28-7 |
DC73946 |
CKi-6
CKi-6 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells. |
2768295-15-2 |
DC73947 |
Cl-NIO
Cl-NIO is a potent, selective inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 1.3 uM, > 500-fold selectivity against arginase and endothelial nitric oxide synthase. |
1606129-72-9 |
DC73948 |
CMP05
CMP05 (Endosomolytic compound CMP05) is a novel endosomolytic small-molecule compound that exhibits higher transfection efficiency/ability to induce endosomal escape of oligonucleotides (ONs) than current compounds such as chloroquine. |
|
DC73949 |
CMP05-7
CMP05-7 (Endosomolytic compound CMP05-7) is a novel endosomolytic small-molecule compound that exhibits higher transfection efficiency/ability to induce endosomal escape of oligonucleotides (ONs) than current compounds such as chloroquine. |
1905413-00-4 |
DC73950 |
CNS-11
CNS-11 is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core. |
445218-34-8 |
DC73951 |
CNS-11g
CNS-11g is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core. |
1309162-57-9 |
DC73952 |
Coproporphyrin III
Coproporphyrin III is a diffusible small molecule porphyrin excreted by human-associated Propionibacterium spp., induces Staphylococcus aureus aggregation and biofilm formation, also induces S. aureus to form a plasma-independent surface-attached biofilm. |
14643-66-4 |
DC73953 |
CPAG-1
Featured
CPAG-1 (PGRMC2 activator CPAG-1) is a small-molecule activator of PGRMC2. CPAG-1 treatment had no effect on weight or food intake but treated mice had reduced fasting glycemia and insulin levels. CPAG-1 decreased Rev-Erbα protein in BAT of CPAG-1-treated mice. CPAG-1 also significantly increased labile heme in the nucleus of brown adipocytes from CPAG-1-treated mice within 4 days of treatment. |
2094991-62-3 |
DC73954 |
CPR1-B
CPR1-B is a longer-acting phenylhexanamide mitofusin activator, increases mitochondrial motility in MFN2 T105M expressing mouse DRGs with EC50 of 3.3 nM (Emax=89%). |
2819664-58-7 |
DC73955 |
CQ211
CQ211 is a potent, highly selective RIOK2 inhibitor with Kd of 6.1 nM, shows excellent selectivity to RIOK2 in both enzymatic and cellular assays. |
2648986-65-4 |
DC73956 |
CRS0540
CRS0540 is a potent, selective PolC DNA polymerase inhibitor that has demonstrated good in vitro and in vivo activity against Listeria monocytogenes. |
|
DC73957 |
CT-179
CT-179 is a small molecule inhibitor of protein transcription factor OLIG2 (Oligodendrocyte transcription factor 2), CT-179 is a putative disruptor of OLIG2 homodimerization. |
1996636-69-1 |