Cat. No. | Product name | CAS No. |
DC66433 |
EGFR-IN-80
Featured
EGFR-IN-80 (compound 30) is an EGFR inhibitor with a pIC50 of 10.6. |
171745-13-4 |
DC66434 |
c-Kit-IN-3
Featured
c-Kit-IN-3 (Compound 18) is a potent and selective c-KIT kinase inhibitor with an IC50s of 4 nM, 8 nM for c-KIT wt and c-KIT T670I, respectively. c-Kit-IN-3 displays great potencies against most of the gain-offunction mutations in the juxtamembrane domain, drugresistant mutations in the ATP binding pocket, and activation loops. |
2363169-01-9 |
DC66435 |
NS1652
Featured
NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells. |
1566-81-0 |
DC66436 |
CYP1B1-IN-7
Featured
CYP1B1-IN-7 (compound 2a) is a selective inhibitor of CYP1B1 (IC50: 75 nM). CYP1B1-IN-7 also reverses resistance (IC50: 29 μM) and exhibits cytotoxicity in the CYP1B1-overexpressing MCF-7 cell line that is resistant to Docetaxel (HY-B0011). |
52601-58-8 |
DC66437 |
Firefly luciferase-IN-1
Featured
Firefly luciferase-IN-1 (compound 48) is a highly potent and reversible inhibitor of firefly luciferase with an IC50 value of 0.25 nM. |
2765796-41-4 |
DC66438 | n-[3-(benzyloxy)pyridin-2-yl]benzenesulfonamide Featured | 877459-36-4 |
DC66439 |
Antituberculosis agent-5
Featured
Antituberculosis agent-5 (compound 52) is a nitrofuranylamide derivative, inhibits M. tuberculosis UDP-Gal mutase. Antituberculosis agent-5 inhibits Glf activity with an IC50 value of 99 μM/mL and resists tuberculosis (TB) with a MIC value of 1.6 μg/mL. |
313981-44-1 |
DC66440 | mPEG-DSPE Featured | 178744-28-0 |
DC66441 |
Tubulin inhibitor 11
Featured
Tubulin inhibitor 11 is a potent and orally active tubulin inhibitor. Tubulin inhibitor 11 targets the Colchicine binding site on tubulin, inhibits tubulin polymerization, promotes mitotic blockade and apoptosis. |
2366260-33-3 |
DC66442 |
TASK-1-IN-1
Featured
TASK-1-IN-1 is a potent and selective TASK-1 (Potassium Channel) inhibitor with an IC50 of 148 nM. TASK-1-IN-1 shows a reduced inhibition of TASK-3 channels (IC50 of 1750 nM) and not a significant effect on other K+ channels. TASK-1-IN-1 has anticancer effects. |
600125-11-9 |
DC66443 |
NDH-1 inhibitor-1
Featured
NDH-1 inhibitor-1 (compound 27) is a potent NDH-1 inhibitor with pI50 values of <4, 5.40, 6.15 µM for Bovine SMP (submitochondrial particles), Potato SMP and E. coli, respectively. |
173964-49-3 |
DC66444 |
Antimalarial agent 17
Featured
Antimalarial agent 17 is an antimalarial agent, also acts as a herbicide. Antimalarial agent 17 is photosystem II inhibitor, shows post-emergence herbicidal activity equal to commercial herbicides. |
508187-76-6 |
DC66445 |
Antimicrobial agent-14
Featured
Antimicrobial agent-14, a benzyl thiophene sulfonamide derivative is an antimicrobial agent, with a MIC of 200 μM against Campylobacter coli ATCC33559. Antimicrobial agent-14 can be used for the research of bacterial foodborne gastroenteritis. |
380576-68-1 |
DC66446 |
Anti-Influenza agent 4
Featured
Anti-Influenza agent 4 is a potent and selective influenza virus inhibitor with EC50s of 150 nM and 62 nM for strains A/Roma and A/Parma, respectively. |
522625-85-0 |
DC66447 |
Antitrypanosomal agent 9
Featured
Antitrypanosomal agent 9 (compound 1) is a potent antitrypanosomal agent. Antitrypanosomal agent 9 shows inhibitory activity against T. b. brucei, with an IC50 of 1.15 μM. Antitrypanosomal agent 9 can be used for human African trypanosomiasis (HAT) research. |
438474-67-0 |
DC66448 |
Neuropeptide Y5 receptor ligand-1
Featured
Neuropeptide Y5 receptor ligand-1 (compound 54), a carbazole derivative, is a potent neuropeptide Y5 (NPY-5) receptor antagonist. |
322723-35-3 |
DC66449 |
Anti-Trypanosoma cruzi agent-4
Featured
Anti-Trypanosoma cruzi agent-4 (compound 5c) is an inhibitor of Trypanosoma cruzi. Anti-Trypanosoma cruzi agent-4 can be used for the research of infection. |
10001-31-7 |
DC66450 |
SPD-473 (citrate)
Featured
SPD-473 citrate is a serotonin/dopamine/norepinephrine reuptake inhibitior. |
161190-26-7 |
DC60597 |
AZD0780
Featured
AZD0780 is the first oral small molecule PCSK9 inhibitor for the treatment of hypercholesterolemia. |
2455427-91-3 |
DC66451 |
Teriparatide
Featured
Teriparatide Free Base can treat osteoporosis in men and in women who have gone through menopause. |
52232-67-4 |
DC66452 |
Survodutide
Featured
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake. |
2805997-46-8 |
DC66453 |
FOXO4-DRI
Featured
FOXO4-DRI is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53. FOXO4-DRI is a senolytic peptide that induces apoptosis of senescent cells. |
2460055-10-9 |