Cat. No. | Product name | CAS No. |
DC66531 | 3-Chloro-6-(trifluoromethyl)pyridazine Featured | 258506-68-2 |
DC66532 | 1H-Pyrazole-3-carboxamide, 5-(1,1-dimethylethyl)-N-(2-hydroxy-1,1-dimethylethyl)-1-[5-(trifluoromethyl)-2-pyridinyl]- Featured | 2374894-45-6 |
DC66533 | UM729 Featured | 1448723-60-1 |
DC66534 |
VK-2019
Featured
VK-2019 is a selective EBNA1 inhibitor. VK-2019 was developed as a highly specific inhibitor of EBNA1 DNA binding activity and is currently in phase 1 development as a treatment for EBV-associated carcinomas. EBNA1 is an Epstein Barr virus (EBV) protein expressed in all EBV-associated cancers. EBNA1 plays a critical role in the replication and maintenance of EBV episomes in latently infected cells. |
2044520-06-9 |
DC66535 | 3-Pyridinecarbonitrile, 1,2,5,6-tetrahydro-4-methyl-2,6-dioxo-5-[(5-phenyl-2-furanyl)methylene]-, (5Z)- Featured | 2378422-35-4 |
DC66536 | SR2640 Featured | 105350-26-3 |
DC66537 | T20 Featured | 146680-14-0 |
DC66538 |
PDE4B-IN-2
Featured
PDE4B-IN-2 is an orally active and selective PDE4B inhibitor with an IC50 of 15 nM. PDE4B-IN-2 inhibits PDE4D (IC50=1.7 µM). PDE4B-IN-2 exhibits potent anti-inflammatory effects. |
915082-52-9 |
DC66539 | methyl 2-((tert-butoxycarbonyl)amino)-4-chlorothiazole-5-carboxylate Featured | 804482-36-8 |
DC66540 |
WAY-380064-A
Featured
PRMT5 inhibitors; PRMT5 inhibitors; |
380192-76-7 |
DC66541 |
NecroX-7
Featured
NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research. |
1120332-55-9 |
DC66542 |
UNC8153 TFA
Featured
UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2)-targeted degrader with a Kd of 24 nM. UNC8153 TFA reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark. UNC8153 TFA contains a simple warhead that confers proteasome-dependent degradation of NSD2. |
2929304-61-8 |
DC60609 |
AK59-51TB (AK59)
Featured
AK59-51TB (AK59) is a STING degrader leveraging HERC4, a HECT-domain E3 ligase. |
|
DC60610 |
IDE397
Featured
IDE397 is a potent inhibitor of MAT2A, which is developed to selectively exploit this synthetic lethal vulnerability in MTAP−/− tumors. |
|
DC60611 |
Compound 32 (HER2)
Featured
Compound 32 (HER2) is a potent and selective covalent inhibitor of HER2/WT and HER2/YVMA with IC50 of 49 nM and 42 nM, respectively. |
|
DC60612 |
IDOR-1117-2520
Featured
IDOR-1117-2520 is a selective and insurmountable antagonist of CCR6 with IC50 of 20 nM. |
|
DC66543 |
Pidobenzone
Featured
Pidobenzone is a dermatologic agent. |
138506-45-3 |
DC66544 |
Pseudouridine 5'-triphosphate trisodium
Featured
Pseudouridine-5’-triphosphate (Pseudo-UTP) is one of the most commonly used modified nucleoside for the polymerase-mediated synthesis of RNA molecules. Compared with uridine-containing unmodified mRNAs, the application of pseudouridine-containing modified mRNAs exhibits better nuclease stability, immunogenicity, and translational properties. |
|
DC66545 | 5-Bromo Brassinin Featured | 1076199-55-7 |
DC60613 |
LSN3441732
Featured
LSN3441732 is a dimeric compound and inhibits the formation of Lipoprotein(a) (Lp(a)) particles in vitro with IC50 of 0.18 nM. |
|
DC66546 |
R-Sirpiglenastat
Featured
R-Sirpiglenastat is the R- isomer of Sirpiglenastat(DRP-104).Sirpiglenastat (DRP104) is a broad acting glutamine antagonist. Sirpiglenastat has anticancer effects by directly targeting tumor metabolism and simultaneously inducing a potent antitumor immune response. |
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DC66547 | SL25 intermediate 16 Featured | 185835-91-0 |