Cat. No. | Product name | CAS No. |
DC66561 | Peracetylated GalNAc succinimidyl pentanoate Featured | |
DC66562 | Peracetylated GalNAc-C3-Amine-1 Featured | |
DC66563 | Peracetylated GalNAc-L96-Acid-2 Featured | |
DC66564 | Peracetylated GalNAc PEG linker-Acid-1 Featured | |
DC66565 | Peracetylated GalNAc-L96-Acid-1 Featured | |
DC66566 | Peracetylated GalNAc-L96-Amide-1 Featured | |
DC66568 | Peracetylated GalNAc PEG linker-Amino-1 Featured | |
DC66569 | GalNAc-L96-Amide Featured | |
DC66570 | NAG-37 Featured | |
DC66571 | Peracetylated GalNAc -C3-Amino-1 Featured | |
DC66572 | Peracetylated GalNAc PEG linker-Amino-2 Featured | |
DC66573 | (S)-L-giutamic acid cbz Featured | |
DC66574 | Peracetylated GalNAc-L96-1 Featured | |
DC66575 | Peracetylated GalNAc PEG linker-Acid-2 Featured | |
DC60617 |
dWIZ-1
Featured
dWIZ-1 is a molecular glue degrader of the WIZ transcription factor that robustly induce HbF in erythroblasts. dWIZ-1 increases CRBNWIZ association with EC50 of 547 nM. |
|
DC60618 |
dWIZ-2
Featured
dWIZ-2 is a molecular glue degrader of the WIZ transcription factor that robustly induce HbF in erythroblasts. dWIZ-2 shows improved pharmacokinetic (PK) properties than dWIZ-1. |
|
DC60619 |
12T-O14
Featured
12T-O14 is a amidine-incorporated degradable (AID) lipid for versatile mRNA delivery. 12T-O14-LNPs mediate efficient intramuscular delivery of mRNA vaccines and systemic delivery of mRNA therapeutics without noticeable toxicity. 12T-O14 serves as a superior supplementary lipid to redirect liver-tropic LNPs to selectively target the lung or spleen via simple adjustment of the formulation. |
|
DC60620 |
REM0046127 (REM127)
Featured
REM0046127 (REM127) is a ReS19-T compound and restores calcium homeostasis and neutralizes tau- and Aβ-driven neurotoxicity. REM127 reduces toxicity and [Ca2+]cyto with EC50 of 15 and 19 nM, respectively but has no effect on tau expression or ATRA-dependent gene transcription. |
|
DC60621 |
MK-1084
Featured
MK-1084 is an orally bioavailable and low-dose KRAS/G12C covalent inhibitor with IC50 of 1.2 nM (GNE) and 9 nM (p-ERK), respectively. |
|
DC60622 |
KM822
Featured
KM822 is avselective, noncompetitive modulator of human dopamine transporter (DAT) with IC50 3.7 μM, which shows 30 and 50 folds higher than for human norepinephrine transporter (hNET) and human serotonin transporter (SERT), respectively. |
|
DC60623 |
CNDR-51997
Featured
CNDR-51997 is a brain-penetrant microtubule alterations-stabilizing small molecule and reduces both Aβ plaque and tau inclusion pathology in established mouse models of Alzheimer's disease. |
|
DC60624 |
OPB-171775
Featured
OPB-171775 is a non-TKI compound that exhibits significant anticancer activity against gastrointestinal stromal tumor (GIST) regardless of KIT mutation status. OPB-171775 induces targeted cell death by inducing a complex between phosphodiesterase 3A (PDE3A) and Schlafen family member 12 (SLFN12). |