Cat. No. | Product name | CAS No. |
DC66576 | Peracetylated GalNAc-L96-Acid-1 Featured | 200133-16-0 |
DC66577 | Propargyl PEG Linker Phosphoramidite Featured | |
DC66578 | Cluster Featured | |
DC66581 | C3-Phosphoramidites Featured | |
DC60625 |
NF764
Featured
NF764 is an analogue of EN83 (CTNNB1 degrader) with improved potency with DC50 of 3.5 nM. NF764 only adducts C619 and shows much more selective than EN83 with 61 significant off-targets. |
|
DC60626 |
EN83
Featured
EN83 is a monovalent degrader of CTNNB1 that directly and covalently targets CTNNB1 three cysteines C466, C520, and C619, leading to destabilization and degradation of CTNNB1. |
|
DC60627 |
DHSEH
Featured
DHSEH is a sulfonium lipid for lung-specific mRNA delivery. |
|
DC60628 |
DOSEH
Featured
DOSEH is a sulfonium lipid for lung-specific mRNA delivery. |
|
DC60630 |
Bivamelagon (Synonyms: MC-4R Agonist 2)
Featured
Bivamelagon is a melanocortin receptor agonist. |
2641595-54-0 |
DC66585 |
Turbinaric acid
Featured
Turbinaric acid is a moderately cytotoxic secosqualene carboxylic acid that is isolated from the brown alga Turbinaria ornata. |
56882-00-9 |
DC66586 |
IDH1 Inhibitor 8
Featured
IDH1 Inhibitor 8 (91) is isocitrate dehydrogenase 1 (IDH1) inhibitor. IDH1 Inhibitor 8 can be used for the research of cancer. |
1448346-63-1 |
DC66587 |
SDPC
Featured
SDPC (DHA-PC) is a new generation of omega-3 lipids, which contains an ester bond linking DHA at the sn-2 position of phospholipid. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine exerts anti-angiogenesis effect through activating PPARγ. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine significantly declines the proliferation, migration, tube formation of human umbilical vein endothelial cells. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine has the potential for anti-tumor angiogenesis research. |
59403-52-0 |
DC60631 |
T-10418
Featured
T-10418 is a potent and selective G2A agonist with EC50 of 0.82 μM. T-10418 exhibits higher potency than the reference and natural ligand 9-HODE and high selectivity among G protein-coupled receptors. T-10418 is a suitable candidate for in vivo studies on therapeutic potential of G2A agonism. |
|
DC60632 |
Lipid TG6A
Featured
TG6A is a biodegradable and ionizable glycerolipid for cmRNA delivery. TG6A-LNP exhibits above 9-fold and 41-fold higher EGFP protein expression in MSCs than DLin-MC3-DMA-LNP and ALC-0315-LNP, respectively. |
|
DC60633 |
AZ9567
Featured
AZ'9567 is a potent inhibitor of MAT2A with pIC50 of 8.2. in vitro with excellent preclinical pharmacokinetic properties. AZ'9567 shows robust antitumor response in the MTAP KO HCT116 model. |
|
DC60634 |
LL-K12-18
Featured
LL-K12-18 is a dual-site molecular glue for CDK12-DDB1 complex with EC50 of 0.37 nM. LL-K12-18 shows an 80-fold enhanced potency than SR-4835 in MDA-MB-231 cells and with a 307-fold boost potency (EC50 = 0.03 nM) in MDA-MB-468 cells, while the degradation efficiency (DC50 = 0.38 nM) increased 50-fold. |
|
DC60635 |
DS18
Featured
DS18 is a DDB1-CDK12 molecular glue with EC50 of 8.771 nM. |
|
DC82210 |
A1-D1-5
Featured
Lipid A1-D1-5 is an ionizable lipid-like substance used for RNA interference therapy in heat-stable ionizable lipid-like nanoparticles (iLAND) for the treatment of hyperlipidemia. |
2877013-53-9 |
DC66588 |
GlyRS-IN-1
Featured
GlyRS-IN-1 is a glycyl-tRNA synthase (GlyRS) inhibitor extracted from patent WO 2017066459 A1. GlyRS-IN-1 can also inhibit the growth of bacteria. |
112921-11-6 |
DC66589 | 1,4,7,10-Tetraoxa-13,16-diazacyclooctadecane Featured | 75173-44-3 |
DC66590 | 3-Pyrrolidinol, 5-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-, hydrochloride (1:1), (3S,5R)- Featured | 864074-65-7 |
DC66591 | 5-bromo-1H-pyrrolo[2,3-b]pyridine-2,3-dione Featured | 149142-67-6 |