Cat. No. | Product name | CAS No. |
DC44475 |
Azido-PEG10-CH2COOH
Azido-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44476 |
Azido-PEG2-C6-OH
Azido-PEG2-C6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44477 |
Propanol-PEG4-CH2OH
Propanol-PEG4-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
156868-17-6 |
DC44478 |
Propanol-PEG5-CH2OH
Propanol-PEG5-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44479 |
Benzyloxy-C5-PEG1
Benzyloxy-C5-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
159028-70-3 |
DC44480 |
Benzyl-PEG2-ethoxyethane-PEG2
Benzyl-PEG2-ethoxyethane-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2115897-18-0 |
DC44481 |
Hydroxy-PEG2-CH2CH2COO-PEG2-propionic acid
Hydroxy-PEG2-CH2CH2COO-PEG2-propionic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44482 |
Dimethylamino-PEG3
Dimethylamino-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2741-30-2 |
DC44483 |
Ph-PEG3
Ph-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
7204-16-2 |
DC44484 |
THP-C4-PEG4
THP-C4-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44485 |
I-PEG5-OH
I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1883516-31-1 |
DC44486 |
Bromo-PEG7-alcohol
Bromo-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
86220-35-1 |
DC44487 |
Benzyl-PEG9-alcohol
Benzyl-PEG9-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
868594-48-3 |
DC44488 |
Benzyl-PEG10-alcohol
Benzyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
908258-44-6 |
DC44489 |
Dimethylamino-PEG11
Dimethylamino-PEG11 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44490 |
Propargyl-PEG11-alcohol
Propargyl-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44491 |
Benzyl-PEG11-alcohol
Benzyl-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44492 |
Benzyl-PEG12-alcohol
Benzyl-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2218463-17-1 |
DC44493 |
Benzyl-PEG13-alcohol
Benzyl-PEG13-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44494 |
Benzyl-PEG14-alcohol
Benzyl-PEG14-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44495 |
Hydroxy-PEG14-t-butyl ester
Hydroxy-PEG14-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44496 |
Benzyl-PEG15-alcohol
Benzyl-PEG15-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44497 |
THP-PEG16-alcohol
THP-PEG16-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44498 |
Benzyl-PEG16-alcohol
Benzyl-PEG16-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44499 |
Benzyl-PEG18-alcohol
Benzyl-PEG18-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44500 |
Benzyl-PEG20-alcohol
Benzyl-PEG20-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44501 |
Benzyl-PEG24-alcohol
Benzyl-PEG24-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2218463-19-3 |
DC44502 |
Benzyl-PEG36-alcohol
Benzyl-PEG36-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44503 |
Hydroxy-PEG3-MS
Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
139115-89-2 |
DC44504 |
Thiol-PEG-COOH (MW 5000)
Thiol-PEG-COOH (MW 5000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|
DC44505 |
Amino-PEG4-C2-SH hydrochloride
Amino-PEG4-C2-SH hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44506 |
Amine-PEG6-thiol
Amine-PEG6-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44507 |
Amino-PEG7-C2-SH hydrochloride
Amino-PEG7-C2-SH hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44509 |
Desmethyl-QCA276
Desmethyl-QCA276 (PROTAC BRD4-binding moiety 4), the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM. |
2126819-55-2 |
DC44510 |
SLF TFA
SLF TFA is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC50 of 2.6 μM for FKBP12. SLF TFA can be used in the synthesis of PROTAC. |
2378802-47-0 |
DC44609 |
F-PEG2-S-Boc
F-PEG2-S-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44610 |
Boc-NH-PEG12-NH-Boc
Boc-NH-PEG12-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44611 |
m-PEG8-amide-C10-Thiol
m-PEG8-amide-C10-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44612 |
THP-PEG1-THP
THP-PEG1-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44613 |
Thiol-PEG4-amide-NH2
Thiol-PEG4-amide-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44614 |
Thiol-C9-PEG5-acid
Thiol-C9-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44615 |
Azido-PEG4-Thiol
Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44616 |
NHS-bis-PEG2-amide-Mal
NHS-bis-PEG2-amide-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44617 |
Bis-(Mal-PEG3)-PH-N-succinimidyl acetate
Bis-(Mal-PEG3)-PH-N-succinimidyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44618 |
Benzyl-PEG4-acyl chloride
Benzyl-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44619 |
NHS ester-PEG7-COOH
NHS ester-PEG7-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44620 |
NHS ester-PEG10-COOH
NHS ester-PEG10-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44621 |
NHS ester-PEG13-COOH
NHS ester-PEG13-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44622 |
Iodoacetamido-PEG6-acid
Iodoacetamido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44623 |
Mal-PEG12-NH-Boc
Mal-PEG12-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44624 |
F-PEG2-S-COOH
F-PEG2-S-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44625 |
F-PEG2-SO-COOH
F-PEG2-SO-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44626 |
F-PEG2-SO2-COOH
F-PEG2-SO2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44627 |
Bromo-PEG9-Boc
Bromo-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44628 |
Bromo-PEG12-acid
Bromo-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44629 |
Benzyl-PEG9-Boc
Benzyl-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44630 |
VES-POFP
VES-POFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44631 |
Amino-PEG2-CH2CH2-SH hydrochloride
Amino-PEG2-CH2CH2-SH (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44632 |
Bromo-PEG10-t-butyl ester
Bromo-PEG10-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44633 |
Bromo-PEG12-t-butyl ester
Bromo-PEG12-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44634 |
Biotin-PEG3-methyl ethanethioate
Biotin-PEG3-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44635 |
Biotin-PEG3-pyridinrthiol
Biotin-PEG3-pyridinrthiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44636 |
Biotin-PEG2-SH
Biotin-PEG2-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44637 |
Fmoc-N-amido-PEG5-azide
Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44638 |
THP-PEG12-alcohol
THP-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44639 |
NHS ester-PEG3-S-methyl ethanethioate
NHS ester-PEG3-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44640 |
Fmoc-N-amido-PEG2-azide
Fmoc-N-amido-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44641 |
Bromo-PEG4-PFP ester
Bromo-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44642 |
Azido-PEG4-acyl chloride
Azido-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44643 |
Azido-PEG8-Mal
Azido-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44644 |
Br-PEG7-NHBoc
Br-PEG7-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44645 |
CG-PEG5-azido
CG-PEG5-azido is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44646 |
CH2COOH-PEG12-CH2COOH
CH2COOH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44647 |
Desthiobiotin-PEG4-acid
Desthiobiotin-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44648 |
NH2-PEG3500-NH2
NH2-PEG3500-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC44649 |
Fmoc-NH-PEG3-amide-CH2OCH2COOH
Fmoc-NH-PEG3-amide-CH2OCH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
489427-26-1 |
DC44650 |
PEG2-Cl
PEG2-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
78925-46-9 |
DC44651 |
Trt-PEG4-C2-acid hydrate
Trt-PEG4-C2-acid (hydrate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1189873-11-7 |
DC44652 |
Benzyl-PEG8-alcohol
Benzyl-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
477775-73-8 |
DC44653 |
CH2COOH-PEG6-CH2COOH
CH2COOH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
83824-29-7 |
DC44654 |
Nonylbenzene-PEG5-OH
Nonylbenzene-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
20636-48-0 |
DC44655 |
Biotin-PEG3-CH2COOH
Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1189560-96-0 |
DC44656 |
Tetraethylene glycol monohexadecyl ether
Tetraethylene glycol monohexadecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
5274-63-5 |
DC44657 |
Fmoc-N-amido-PEG2-alcohol
Fmoc-N-amido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
299430-87-8 |
DC44658 |
Benzyl-PEG4-MS
Benzyl-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
477781-69-4 |
DC44659 |
Ethyl-PEG4-alcohol
Ethyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
5650-20-4 |
DC44660 |
t-Butyl acetate-PEG3-CH2COOH
t-Butyl acetate-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1442466-57-0 |
DC44661 |
Methyl-PEG3-bromide
Methyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
72593-77-2 |
DC44662 |
Tos-PEG2-OH
Tos-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
118591-58-5 |
DC44663 |
endo-BCN-PEG2-NH2
endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1263166-93-3 |
DC44664 |
THP-PEG1-alcohol
THP-PEG1-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2162-31-4 |
DC44665 |
Methyl-PEG2-alcohol
Methyl-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
111-77-3 |
DC44666 |
Cl-PEG2-acid
Cl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
170304-76-4 |
DC44667 |
THP-CH3-ethyl propionate
THP-CH3-ethyl propionate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
3539-40-0 |
DC44668 |
Thiol-C10-amide-PEG8
Thiol-C10-amide-PEG8 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1353948-95-4 |
DC44669 |
Thiol-C9-PEG5
Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
130727-42-3 |
DC44670 |
Thiol-C9-PEG4
Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
130727-41-2 |
DC44671 |
5-[Boc(methyl)amino]pentanal
5-[Boc(methyl)amino]pentanal is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
1620280-47-8 |
DC44672 |
Azido-PEG3-aldehyde
Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1807530-10-4 |
DC44673 |
Thiol-C9-PEG7
Thiol-C9-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
130727-44-5 |
DC44674 |
CH2COOH-PEG9-CH2COOH
CH2COOH-PEG9-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2250056-46-1 |
DC44675 |
Bis-PEG2-Boc
Bis-PEG2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
1611468-28-0 |
DC44676 |
Biotin-PEG3-propargyl
Biotin-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1421701-68-9 |
DC44677 |
F-PEG2-COOH
F-PEG2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2383964-72-3 |
DC44678 |
Boc-NH-PPG2
Boc-NH-PPG2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
1312905-31-9 |
DC44679 |
HO-PEG5-CH2COOH
HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
52026-48-9 |
DC44680 |
Propargyl-PEG2-urea-C3-triethoxysilane
Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1637329-79-3 |
DC44681 |
Boc-NHCH2CH2-PEG1-azide
Boc-NHCH2CH2-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
176220-30-7 |
DC44682 |
Biotin-PEG3-SH
Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1244028-52-1 |
DC44683 |
Fmoc-N-amido-PEG3-azide
Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1172605-58-1 |
DC44684 |
Benzyl-PEG3-MS
Benzyl-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
702701-70-0 |
DC44685 |
MS-PEG3-THP
MS-PEG3-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
357204-84-3 |
DC44686 |
Benzyl-PEG7-THP
Benzyl-PEG7-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
230620-75-4 |
DC44687 |
Benzyl-PEG6-THP
Benzyl-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
230620-73-2 |
DC44688 |
Bis-CH2-PEG2-acid
Bis-CH2-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2250056-38-1 |
DC44689 |
Amino-PEG7-t-butyl ester
Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2428400-07-9 |
DC44690 |
Thiol-PEG2-t-butyl ester
Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1398044-50-2 |
DC44691 |
Methyl-PEG4-acyl chloride
Methyl-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
62124-69-0 |
DC44692 |
Azido-PEG9-S-methyl ethanethioate
Azido-PEG9-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2148986-33-6 |
DC44693 |
Azido-PEG5-S-methyl ethanethioate
Azido-PEG5-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1352221-64-7 |
DC44694 |
Methyl-PEG3-Ald
Methyl-PEG3-Ald is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
141981-62-6 |
DC44695 |
Propargyl-PEG9-acid
Propargyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1613752-50-3 |
DC44696 |
Thiol-C9-PEG4-acid
Thiol-C9-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
716339-41-2 |
DC44697 |
Nonylbenzene-PEG8-OH
Nonylbenzene-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
41506-14-3 |
DC44698 |
Bromo-PEG7-azide
Bromo-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1056969-61-9 |
DC44699 |
t-Butyl acetate-PEG2-CH2COOH
t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
883564-93-0 |
DC44700 |
Cyclohexane-PEG1-Br
Cyclohexane-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
131665-94-6 |
DC44701 |
BocNH-PEG5-CH2CH2Br
BocNH-PEG5-CH2CH2Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1392499-33-0 |
DC44702 |
Tos-PEG3-CH2COOtBu
Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1530778-24-5 |
DC53120 |
XD2-149
Featured
XD2-149 is a napabucasin PROTAC as an effective degrader of the E3 ligase ZFP91 with IC50 of 1 μM and 0.8 μM in pancreatic cancer cell lines, MIA PaCa-2 and BxPC-3, respectively. XD2-149 also reduces the expression of STAT3, pSTAT3, and NQO1 proteins. |
|
DC44798 |
ARV-110
Featured
ARV-110 is an orally active, specific androgen receptor (AR) PROTAC degrader. ARV-110 promotes ubiquitination and degradation of AR. ARV-110 can be used for the research of prostate cancer. |
2222112-77-6 |
DC44905 |
Vepdegestrant (ARV-471)
Featured
ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer. |
2229711-68-4 |
DC45199 |
PROTAC BRD4 Degrader-10
PROTAC BRD4 Degrader-10 (compound 8b) is a potent BRD4 degrader. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively. |
2417370-49-9 |
DC45200 |
PROTAC BRD4 Degrader-12
PROTAC BRD4 Degrader-12 (compound 9c) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively. |
2417370-90-0 |
DC45201 |
PROTAC BRD4 Degrader-13
Featured
PROTAC BRD4 Degrader-13 (compound 9d) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-13 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.025 nM and 6.0 nM, respectively. |
2417370-71-7 |
DC45202 |
PROTAC BRD4 Degrader-11
PROTAC BRD4 Degrader-11 (compound 9a) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-11 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.23 nM and 0.38 nM, respectively. |
|
DC45203 |
PROTAC BRD4 Degrader-14
PROTAC BRD4 Degrader-14 is a potent BRD4 degrader, with IC50s of 1.8 nM and 1.7 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-14 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells. |
|
DC45204 |
PROTAC BRD4 Degrader-8
PROTAC BRD4 Degrader-8 is a potent BRD4 inhibitor, with IC50s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells. |
|
DC45205 |
PROTAC BRD4 Degrader-9
PROTAC BRD4 Degrader-9 (compound 8a) is a potent BRD4 degrader. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively. |
2417370-42-2 |
DC45206 |
Bis-sulfone-PEG4-DBCO
Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1854034-70-0 |
DC45207 |
Azido-PEG2-propargyl
Azido-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1245006-63-6 |
DC45208 |
Propargyl-PEG2-NHS ester
Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2512228-06-5 |
DC45209 |
m-PEG5-Propyne
m-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1101668-41-0 |
DC45210 |
S-acetyl-PEG4-amine
S-acetyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1404111-71-2 |
DC45211 |
S-acetyl-PEG5-alcohol
S-acetyl-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1000415-61-1 |
DC45212 |
Propargyl-PEG5-Br
Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1287660-83-6 |
DC45213 |
Mal-amido-PEG3-acid
Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2055353-75-6 |
DC45214 |
S-acetyl-PEG4-NHBoc
S-acetyl-PEG4-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1404111-70-1 |
DC45215 |
Pyrene azide 3
Pyrene azide 3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2252168-06-0 |
DC45216 |
Mal-amido-PEG3-NHS ester
Mal-amido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2055353-77-8 |
DC45217 |
(E)-TCO-PEG4-NHS ester
(E)-TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1621096-79-4 |
DC45218 |
Azido-PEG12-propargyl
Azido-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2264091-72-5 |
DC45219 |
Azido-PEG12-alcohol
Azido-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1111239-69-0 |
DC45220 |
Benzyl-PEG9-Ots
Benzyl-PEG9-Ots is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
393517-91-4 |
DC45221 |
Mal-amido-PEG9-NHS ester
Mal-amido-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2575631-92-2 |
DC45222 |
Biotin-PEG3-Bis-sulfone
Biotin-PEG3-Bis-sulfone is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2055048-58-1 |
DC45223 |
PC DBCO-PEG4-NHS ester
PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
2055025-02-8 |
DC45224 |
Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride
Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. |
174422-72-1 |
DC45225 |
Azido-PEG4-azide
Azido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
182760-73-2 |
DC45226 |
Benzyl-PEG4-Azido
Benzyl-PEG4-Azido is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
86770-71-0 |
DC45227 |
Benzyl-PEG4-Ots
Benzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
89346-82-7 |
DC45228 |
m-PEG9-azide
m-PEG9-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
1354521-95-1 |
DC45229 |
Azido-PEG8-azide
Azido-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
361543-07-9 |
DC45230 |
Benzyl-PEG5-Ots
Benzyl-PEG5-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
129086-10-8 |
DC45231 |
Benzyl-PEG6-Ots
Benzyl-PEG6-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
129086-11-9 |
DC45232 |
Azido-PEG8-NHBoc
Azido-PEG8-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
2231845-12-6 |
DC45233 |
Benzyl-PEG7-Ots
Benzyl-PEG7-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|
DC45234 |
Benzyl-PEG8-Ots
Benzyl-PEG8-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
1144113-17-6 |
DC45235 |
m-PEG13-azide
m-PEG13-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45236 |
DBCO-PEG13-NHS ester
DBCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45237 |
S-acetyl-PEG4-Thiol
S-acetyl-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45238 |
Propargyl-PEG7-amine
Propargyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45239 |
m-PEG5-amino-Mal
m-PEG5-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45240 |
Propargyl-PEG7-Br
Propargyl-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45241 |
Mal-amido-PEG5-acid
Mal-amido-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45242 |
Azido-PEG7-NHS ester
Azido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45243 |
Propargyl-PEG11-amine
Propargyl-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45244 |
Propargyl-PEG11-acid
Propargyl-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45245 |
Mal-PEG10-acid
Mal-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45246 |
Propargyl-PEG12-acid
Propargyl-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45247 |
Propargyl-PEG13-OH
Propargyl-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45248 |
Mal-amido-PEG7-NHS ester
Mal-amido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45249 |
Mal-PEG10-Boc
Mal-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45250 |
Mal-PEG10-NHS ester
Mal-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45251 |
Propargyl-PEG13-Boc
Propargyl-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45252 |
m-PEG14-NHS ester
m-PEG14-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45253 |
Fmoc-PEG9-NHS ester
Fmoc-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45254 |
Fmoc-PEG10-NHS ester
Fmoc-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45255 |
Bis-sulfone-PEG4-Tetrazine
Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45256 |
Azido-PEG10-propargyl
Azido-PEG10-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45257 |
Benzyl-PEG10-Ots
Benzyl-PEG10-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|
DC45258 |
Benzyl-PEG12-Ots
Benzyl-PEG12-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|
DC55003 |
XY028-140 (MS140)
Featured
XY028-140 (MS-140) is a potent and selective PROTAC-based CDK4/CDK6 kinase degrader. XY028-140 specifically inhibits RB-E2F signaling and reduces CDK4 and CDK6 protein levels in a dose- and time-dependent manner in vitro. In addition, XY028-140 can degrade its targets by linking them with ubiquitin-proteasome mechanism. Further, the degradation of CDK4/6 protein by XY028-140 is specifically mediated by CRBN. Therefore, XY028-140 effectively and selectively inhibits and degrades CDK4/6 kinase by targeting CDK4/6 kinase in CDK4/6i-S (CDK4/6 inhibitor-sensitive) tumor cells to the CRL4-CRBN-E3 ubiquitin complex. Compared with CDK6 wild-type cells, XY028-140 treatment of cells expressing wild-type or mutation-activated CDK6 resulted in a more effective degradation of CDK6 (S178P). |
2229974-83-6 |
DC45754 |
ACBI1
Featured
ACBI1 is a potent and cooperative PROTAC degrader of SMARCA2, SMARCA4 and PBRM1 with DC50 of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 induces anti-proliferative effects and apoptosis. |
2375564-55-7 |
DC45755 |
Bis-PEG12-endo-BCN
Bis-PEG12-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
DC45756 |
5-Boc-amino-pentanoic acid
5-Boc-amino-pentanoic acid (Boc-5-aminovaleric acid, Boc-NH-C4-acid, Boc-5-Ava-OH) is a PROTAC linker that belongs to a Alkyl/ether linker. Boc-NH-C4-acid is applicable to the synthesis of PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex. |
27219-07-4 |
DC45853 |
PROTAC BRD4 Degrader-15
PROTAC BRD4 Degrader-15 is a potent BRD4 degrader, with IC50s of 7.2 nM and 8.1 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-15 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells. |
2417370-67-1 |
DC45855 |
PROTAC IRAK4 degrader-4
PROTAC IRAK4 degrader-4 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-127. |
2360528-45-4 |
DC45856 |
PROTAC IRAK4 degrader-6
PROTAC IRAK4 degrader-6 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-172. |
2360530-72-7 |
DC46178 |
PROTAC KRAS G12C degrader-1
PROTAC KRAS G12C degrader-1 is a PROTAC-based KRASG12C degrader, with an IC50 of 414 nM for CRBN. PROTAC KRAS G12C degrader-1 induces CRBN/ KRASG12C dimerization and degrades GFP- KRASG12C in reporter cells. |