Home > PROTACs > PROTAC
Cat. No. Product name CAS No.
DC44475 Azido-PEG10-CH2COOH

Azido-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44476 Azido-PEG2-C6-OH

Azido-PEG2-C6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44477 Propanol-PEG4-CH2OH

Propanol-PEG4-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

156868-17-6
DC44478 Propanol-PEG5-CH2OH

Propanol-PEG5-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44479 Benzyloxy-C5-PEG1

Benzyloxy-C5-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

159028-70-3
DC44480 Benzyl-PEG2-ethoxyethane-PEG2

Benzyl-PEG2-ethoxyethane-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2115897-18-0
DC44481 Hydroxy-PEG2-CH2CH2COO-PEG2-propionic acid

Hydroxy-PEG2-CH2CH2COO-PEG2-propionic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44482 Dimethylamino-PEG3

Dimethylamino-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2741-30-2
DC44483 Ph-PEG3

Ph-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

7204-16-2
DC44484 THP-C4-PEG4

THP-C4-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44485 I-PEG5-OH

I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1883516-31-1
DC44486 Bromo-PEG7-alcohol

Bromo-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

86220-35-1
DC44487 Benzyl-PEG9-alcohol

Benzyl-PEG9-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

868594-48-3
DC44488 Benzyl-PEG10-alcohol

Benzyl-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

908258-44-6
DC44489 Dimethylamino-PEG11

Dimethylamino-PEG11 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44490 Propargyl-PEG11-alcohol

Propargyl-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44491 Benzyl-PEG11-alcohol

Benzyl-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44492 Benzyl-PEG12-alcohol

Benzyl-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2218463-17-1
DC44493 Benzyl-PEG13-alcohol

Benzyl-PEG13-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44494 Benzyl-PEG14-alcohol

Benzyl-PEG14-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44495 Hydroxy-PEG14-t-butyl ester

Hydroxy-PEG14-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44496 Benzyl-PEG15-alcohol

Benzyl-PEG15-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44497 THP-PEG16-alcohol

THP-PEG16-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44498 Benzyl-PEG16-alcohol

Benzyl-PEG16-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44499 Benzyl-PEG18-alcohol

Benzyl-PEG18-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44500 Benzyl-PEG20-alcohol

Benzyl-PEG20-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44501 Benzyl-PEG24-alcohol

Benzyl-PEG24-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2218463-19-3
DC44502 Benzyl-PEG36-alcohol

Benzyl-PEG36-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44503 Hydroxy-PEG3-MS

Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

139115-89-2
DC44504 Thiol-PEG-COOH (MW 5000)

Thiol-PEG-COOH (MW 5000) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

DC44505 Amino-PEG4-C2-SH hydrochloride

Amino-PEG4-C2-SH hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44506 Amine-PEG6-thiol

Amine-PEG6-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44507 Amino-PEG7-C2-SH hydrochloride

Amino-PEG7-C2-SH hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44509 Desmethyl-QCA276

Desmethyl-QCA276 (PROTAC BRD4-binding moiety 4), the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM.

2126819-55-2
DC44510 SLF TFA

SLF TFA is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC50 of 2.6 μM for FKBP12. SLF TFA can be used in the synthesis of PROTAC.

2378802-47-0
DC44609 F-PEG2-S-Boc

F-PEG2-S-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44610 Boc-NH-PEG12-NH-Boc

Boc-NH-PEG12-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44611 m-PEG8-amide-C10-Thiol

m-PEG8-amide-C10-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44612 THP-PEG1-THP

THP-PEG1-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44613 Thiol-PEG4-amide-NH2

Thiol-PEG4-amide-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44614 Thiol-C9-PEG5-acid

Thiol-C9-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44615 Azido-PEG4-Thiol

Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44616 NHS-bis-PEG2-amide-Mal

NHS-bis-PEG2-amide-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44617 Bis-(Mal-PEG3)-PH-N-succinimidyl acetate

Bis-(Mal-PEG3)-PH-N-succinimidyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44618 Benzyl-PEG4-acyl chloride

Benzyl-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44619 NHS ester-PEG7-COOH

NHS ester-PEG7-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44620 NHS ester-PEG10-COOH

NHS ester-PEG10-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44621 NHS ester-PEG13-COOH

NHS ester-PEG13-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44622 Iodoacetamido-PEG6-acid

Iodoacetamido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44623 Mal-PEG12-NH-Boc

Mal-PEG12-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44624 F-PEG2-S-COOH

F-PEG2-S-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44625 F-PEG2-SO-COOH

F-PEG2-SO-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44626 F-PEG2-SO2-COOH

F-PEG2-SO2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44627 Bromo-PEG9-Boc

Bromo-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44628 Bromo-PEG12-acid

Bromo-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44629 Benzyl-PEG9-Boc

Benzyl-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44630 VES-POFP

VES-POFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44631 Amino-PEG2-CH2CH2-SH hydrochloride

Amino-PEG2-CH2CH2-SH (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44632 Bromo-PEG10-t-butyl ester

Bromo-PEG10-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44633 Bromo-PEG12-t-butyl ester

Bromo-PEG12-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44634 Biotin-PEG3-methyl ethanethioate

Biotin-PEG3-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44635 Biotin-PEG3-pyridinrthiol

Biotin-PEG3-pyridinrthiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44636 Biotin-PEG2-SH

Biotin-PEG2-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44637 Fmoc-N-amido-PEG5-azide

Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44638 THP-PEG12-alcohol

THP-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44639 NHS ester-PEG3-S-methyl ethanethioate

NHS ester-PEG3-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44640 Fmoc-N-amido-PEG2-azide

Fmoc-N-amido-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44641 Bromo-PEG4-PFP ester

Bromo-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44642 Azido-PEG4-acyl chloride

Azido-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44643 Azido-PEG8-Mal

Azido-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44644 Br-PEG7-NHBoc

Br-PEG7-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44645 CG-PEG5-azido

CG-PEG5-azido is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44646 CH2COOH-PEG12-CH2COOH

CH2COOH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44647 Desthiobiotin-PEG4-acid

Desthiobiotin-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44648 NH2-PEG3500-NH2

NH2-PEG3500-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC44649 Fmoc-NH-PEG3-amide-CH2OCH2COOH

Fmoc-NH-PEG3-amide-CH2OCH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

489427-26-1
DC44650 PEG2-Cl

PEG2-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

78925-46-9
DC44651 Trt-PEG4-C2-acid hydrate

Trt-PEG4-C2-acid (hydrate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1189873-11-7
DC44652 Benzyl-PEG8-alcohol

Benzyl-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

477775-73-8
DC44653 CH2COOH-PEG6-CH2COOH

CH2COOH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

83824-29-7
DC44654 Nonylbenzene-PEG5-OH

Nonylbenzene-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

20636-48-0
DC44655 Biotin-PEG3-CH2COOH

Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1189560-96-0
DC44656 Tetraethylene glycol monohexadecyl ether

Tetraethylene glycol monohexadecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

5274-63-5
DC44657 Fmoc-N-amido-PEG2-alcohol

Fmoc-N-amido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

299430-87-8
DC44658 Benzyl-PEG4-MS

Benzyl-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

477781-69-4
DC44659 Ethyl-PEG4-alcohol

Ethyl-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

5650-20-4
DC44660 t-Butyl acetate-PEG3-CH2COOH

t-Butyl acetate-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1442466-57-0
DC44661 Methyl-PEG3-bromide

Methyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

72593-77-2
DC44662 Tos-PEG2-OH

Tos-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

118591-58-5
DC44663 endo-BCN-PEG2-NH2

endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1263166-93-3
DC44664 THP-PEG1-alcohol

THP-PEG1-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2162-31-4
DC44665 Methyl-PEG2-alcohol

Methyl-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

111-77-3
DC44666 Cl-PEG2-acid

Cl-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

170304-76-4
DC44667 THP-CH3-ethyl propionate

THP-CH3-ethyl propionate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

3539-40-0
DC44668 Thiol-C10-amide-PEG8

Thiol-C10-amide-PEG8 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1353948-95-4
DC44669 Thiol-C9-PEG5

Thiol-C9-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

130727-42-3
DC44670 Thiol-C9-PEG4

Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

130727-41-2
DC44671 5-[Boc(methyl)amino]pentanal

5-[Boc(methyl)amino]pentanal is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

1620280-47-8
DC44672 Azido-PEG3-aldehyde

Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1807530-10-4
DC44673 Thiol-C9-PEG7

Thiol-C9-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

130727-44-5
DC44674 CH2COOH-PEG9-CH2COOH

CH2COOH-PEG9-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2250056-46-1
DC44675 Bis-PEG2-Boc

Bis-PEG2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

1611468-28-0
DC44676 Biotin-PEG3-propargyl

Biotin-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1421701-68-9
DC44677 F-PEG2-COOH

F-PEG2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2383964-72-3
DC44678 Boc-NH-PPG2

Boc-NH-PPG2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

1312905-31-9
DC44679 HO-PEG5-CH2COOH

HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

52026-48-9
DC44680 Propargyl-PEG2-urea-C3-triethoxysilane

Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1637329-79-3
DC44681 Boc-NHCH2CH2-PEG1-azide

Boc-NHCH2CH2-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

176220-30-7
DC44682 Biotin-PEG3-SH

Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1244028-52-1
DC44683 Fmoc-N-amido-PEG3-azide

Fmoc-N-amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1172605-58-1
DC44684 Benzyl-PEG3-MS

Benzyl-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

702701-70-0
DC44685 MS-PEG3-THP

MS-PEG3-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

357204-84-3
DC44686 Benzyl-PEG7-THP

Benzyl-PEG7-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

230620-75-4
DC44687 Benzyl-PEG6-THP

Benzyl-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

230620-73-2
DC44688 Bis-CH2-PEG2-acid

Bis-CH2-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2250056-38-1
DC44689 Amino-PEG7-t-butyl ester

Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2428400-07-9
DC44690 Thiol-PEG2-t-butyl ester

Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1398044-50-2
DC44691 Methyl-PEG4-acyl chloride

Methyl-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

62124-69-0
DC44692 Azido-PEG9-S-methyl ethanethioate

Azido-PEG9-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2148986-33-6
DC44693 Azido-PEG5-S-methyl ethanethioate

Azido-PEG5-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1352221-64-7
DC44694 Methyl-PEG3-Ald

Methyl-PEG3-Ald is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

141981-62-6
DC44695 Propargyl-PEG9-acid

Propargyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1613752-50-3
DC44696 Thiol-C9-PEG4-acid

Thiol-C9-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

716339-41-2
DC44697 Nonylbenzene-PEG8-OH

Nonylbenzene-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

41506-14-3
DC44698 Bromo-PEG7-azide

Bromo-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1056969-61-9
DC44699 t-Butyl acetate-PEG2-CH2COOH

t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

883564-93-0
DC44700 Cyclohexane-PEG1-Br

Cyclohexane-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

131665-94-6
DC44701 BocNH-PEG5-CH2CH2Br

BocNH-PEG5-CH2CH2Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1392499-33-0
DC44702 Tos-PEG3-CH2COOtBu

Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1530778-24-5
DC53120 XD2-149 Featured

XD2-149 is a napabucasin PROTAC as an effective degrader of the E3 ligase ZFP91 with IC50 of 1 μM and 0.8 μM in pancreatic cancer cell lines, MIA PaCa-2 and BxPC-3, respectively. XD2-149 also reduces the expression of STAT3, pSTAT3, and NQO1 proteins.

DC44798 ARV-110 Featured

ARV-110 is an orally active, specific androgen receptor (AR) PROTAC degrader. ARV-110 promotes ubiquitination and degradation of AR. ARV-110 can be used for the research of prostate cancer.

2222112-77-6
DC44905 Vepdegestrant (ARV-471) Featured

ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer.

2229711-68-4
DC45199 PROTAC BRD4 Degrader-10

PROTAC BRD4 Degrader-10 (compound 8b) is a potent BRD4 degrader. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively.

2417370-49-9
DC45200 PROTAC BRD4 Degrader-12

PROTAC BRD4 Degrader-12 (compound 9c) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively.

2417370-90-0
DC45201 PROTAC BRD4 Degrader-13 Featured

PROTAC BRD4 Degrader-13 (compound 9d) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-13 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.025 nM and 6.0 nM, respectively.

2417370-71-7
DC45202 PROTAC BRD4 Degrader-11

PROTAC BRD4 Degrader-11 (compound 9a) is a potent chimeric BRD4 degrader. PROTAC BRD4 Degrader-11 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.23 nM and 0.38 nM, respectively.

DC45203 PROTAC BRD4 Degrader-14

PROTAC BRD4 Degrader-14 is a potent BRD4 degrader, with IC50s of 1.8 nM and 1.7 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-14 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells.

DC45204 PROTAC BRD4 Degrader-8

PROTAC BRD4 Degrader-8 is a potent BRD4 inhibitor, with IC50s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells.

DC45205 PROTAC BRD4 Degrader-9

PROTAC BRD4 Degrader-9 (compound 8a) is a potent BRD4 degrader. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively.

2417370-42-2
DC45206 Bis-sulfone-PEG4-DBCO

Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1854034-70-0
DC45207 Azido-PEG2-propargyl

Azido-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1245006-63-6
DC45208 Propargyl-PEG2-NHS ester

Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2512228-06-5
DC45209 m-PEG5-Propyne

m-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1101668-41-0
DC45210 S-acetyl-PEG4-amine

S-acetyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1404111-71-2
DC45211 S-acetyl-PEG5-alcohol

S-acetyl-PEG5-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1000415-61-1
DC45212 Propargyl-PEG5-Br

Propargyl-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1287660-83-6
DC45213 Mal-amido-PEG3-acid

Mal-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2055353-75-6
DC45214 S-acetyl-PEG4-NHBoc

S-acetyl-PEG4-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1404111-70-1
DC45215 Pyrene azide 3

Pyrene azide 3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2252168-06-0
DC45216 Mal-amido-PEG3-NHS ester

Mal-amido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2055353-77-8
DC45217 (E)-TCO-PEG4-NHS ester

(E)-TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1621096-79-4
DC45218 Azido-PEG12-propargyl

Azido-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2264091-72-5
DC45219 Azido-PEG12-alcohol

Azido-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

1111239-69-0
DC45220 Benzyl-PEG9-Ots

Benzyl-PEG9-Ots is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

393517-91-4
DC45221 Mal-amido-PEG9-NHS ester

Mal-amido-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2575631-92-2
DC45222 Biotin-PEG3-Bis-sulfone

Biotin-PEG3-Bis-sulfone is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2055048-58-1
DC45223 PC DBCO-PEG4-NHS ester

PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2055025-02-8
DC45224 Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride

Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

174422-72-1
DC45225 Azido-PEG4-azide

Azido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

182760-73-2
DC45226 Benzyl-PEG4-Azido

Benzyl-PEG4-Azido is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

86770-71-0
DC45227 Benzyl-PEG4-Ots

Benzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

89346-82-7
DC45228 m-PEG9-azide

m-PEG9-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

1354521-95-1
DC45229 Azido-PEG8-azide

Azido-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

361543-07-9
DC45230 Benzyl-PEG5-Ots

Benzyl-PEG5-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

129086-10-8
DC45231 Benzyl-PEG6-Ots

Benzyl-PEG6-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

129086-11-9
DC45232 Azido-PEG8-NHBoc

Azido-PEG8-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

2231845-12-6
DC45233 Benzyl-PEG7-Ots

Benzyl-PEG7-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

DC45234 Benzyl-PEG8-Ots

Benzyl-PEG8-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

1144113-17-6
DC45235 m-PEG13-azide

m-PEG13-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45236 DBCO-PEG13-NHS ester

DBCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45237 S-acetyl-PEG4-Thiol

S-acetyl-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45238 Propargyl-PEG7-amine

Propargyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45239 m-PEG5-amino-Mal

m-PEG5-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45240 Propargyl-PEG7-Br

Propargyl-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45241 Mal-amido-PEG5-acid

Mal-amido-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45242 Azido-PEG7-NHS ester

Azido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45243 Propargyl-PEG11-amine

Propargyl-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45244 Propargyl-PEG11-acid

Propargyl-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45245 Mal-PEG10-acid

Mal-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45246 Propargyl-PEG12-acid

Propargyl-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45247 Propargyl-PEG13-OH

Propargyl-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45248 Mal-amido-PEG7-NHS ester

Mal-amido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45249 Mal-PEG10-Boc

Mal-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45250 Mal-PEG10-NHS ester

Mal-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45251 Propargyl-PEG13-Boc

Propargyl-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45252 m-PEG14-NHS ester

m-PEG14-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45253 Fmoc-PEG9-NHS ester

Fmoc-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45254 Fmoc-PEG10-NHS ester

Fmoc-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45255 Bis-sulfone-PEG4-Tetrazine

Bis-sulfone-PEG4-Tetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45256 Azido-PEG10-propargyl

Azido-PEG10-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45257 Benzyl-PEG10-Ots

Benzyl-PEG10-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

DC45258 Benzyl-PEG12-Ots

Benzyl-PEG12-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

DC55003 XY028-140 (MS140) Featured

XY028-140 (MS-140) is a potent and selective PROTAC-based CDK4/CDK6 kinase degrader. XY028-140 specifically inhibits RB-E2F signaling and reduces CDK4 and CDK6 protein levels in a dose- and time-dependent manner in vitro. In addition, XY028-140 can degrade its targets by linking them with ubiquitin-proteasome mechanism. Further, the degradation of CDK4/6 protein by XY028-140 is specifically mediated by CRBN. Therefore, XY028-140 effectively and selectively inhibits and degrades CDK4/6 kinase by targeting CDK4/6 kinase in CDK4/6i-S (CDK4/6 inhibitor-sensitive) tumor cells to the CRL4-CRBN-E3 ubiquitin complex. Compared with CDK6 wild-type cells, XY028-140 treatment of cells expressing wild-type or mutation-activated CDK6 resulted in a more effective degradation of CDK6 (S178P).

2229974-83-6
DC45754 ACBI1 Featured

ACBI1 is a potent and cooperative PROTAC degrader of SMARCA2, SMARCA4 and PBRM1 with DC50 of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 induces anti-proliferative effects and apoptosis.

2375564-55-7
DC45755 Bis-PEG12-endo-BCN

Bis-PEG12-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DC45756 5-Boc-amino-pentanoic acid

5-Boc-amino-pentanoic acid (Boc-5-aminovaleric acid, Boc-NH-C4-acid, Boc-5-Ava-OH) is a PROTAC linker that belongs to a Alkyl/ether linker. Boc-NH-C4-acid is applicable to the synthesis of PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex.

27219-07-4
DC45853 PROTAC BRD4 Degrader-15

PROTAC BRD4 Degrader-15 is a potent BRD4 degrader, with IC50s of 7.2 nM and 8.1 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-15 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells.

2417370-67-1
DC45855 PROTAC IRAK4 degrader-4

PROTAC IRAK4 degrader-4 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-127.

2360528-45-4
DC45856 PROTAC IRAK4 degrader-6

PROTAC IRAK4 degrader-6 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-172.

2360530-72-7
DC46178 PROTAC KRAS G12C degrader-1

PROTAC KRAS G12C degrader-1 is a PROTAC-based KRASG12C degrader, with an IC50 of 414 nM for CRBN. PROTAC KRAS G12C degrader-1 induces CRBN/ KRASG12C dimerization and degrades GFP- KRASG12C in reporter cells.

<Prev1234Next >