Novel inhibitor of glioma-associated oncogene homologue 1 (Gli1) mediated transcription

Novel Inhibitor of Nonsense-Mediated RNA Decay, Suppressing Nonsense p53 Mutations

Potent and state-dependent Nav1.7 antagonist

Novel Mdm2 inhibitor, acting as a negative regulator of p53, reducing viability in cell culture and suppressing tumor growth

Novel Microtubule Modulator, Blocking Mitosis and Inducing Apoptosis in HeLa Cells by Binding to Tubulin

Covalent and allosteric inhibitor of the ATPase VCP/p97, inducing cancer cell death

Novel selective and orally bioavailable MPS1 inhibitor

Novel JAK2 inhibitor, displaying significant tumor growth inhibition in SET-​2 xenograft tumor model, with a mechanism of action confirmed in vivo by typical modulation of known biomarkers, and with a favorable pharmacokinetic and safety profile

Novel Potent and Highly Selective, Long-Acting, Peptide-Based Cholecystokinin 1 Receptor (CCK-1R) Agonist

Novel inhibitor of autophagy, protecting cardiomyocytes against hypoxia/reoxygenation injury

Novel selective histamine H3 antagonist

Iminosugar, binding to the active site of lysosomal beta-glucosidase and stabilizing the proper folding for the catalytic form, acting as a chemical chaperone that facilitate transport and maturation of acid beta-Glu

Novel potent alkynyl bisubstrate inhibitor of nicotinamide N-methyltransferase (NNMT)

Novel non-nucleoside reverse transcriptase inhibitor (NNRTI)

Moderate antibiotic agent against a broad spectrum of gram-negative bacteria

The universal precursor of the nocardicins

Natural Inhibitor of an Oncogenic RNA, targeting RNA folds in the nuclease processing site in the oncogenic, noncoding microRNA-18a, selectively inhibiting nuclease processing in vitro and in prostate cancer cells and triggering apoptosis

Nocazine family member

Marine natural nocazine family member; Standard used in nocazine biosynthetic parthway studies

Neuropeptide, acting as a endogenous ligand for the nociceptin receptor (NOP, ORL-1)

PPARalpha agonist and EC 3.5.1.23 (ceramidase) inhibitor

Steroidal progestin