Cat. No. | Product name | CAS No. |
DC73499 |
Ogremorphin-1
Ogremorphin-1 (OGM1) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.16 uM. |
352563-21-4 |
DC73500 |
DC591053
DC591053 (DC 591053) is a selective small molecule agonist of relaxin family peptide receptor 4 (RXFP4) with pEC50 of 7.24 and pKi of 6.95, shows no activity against RXFP3. |
|
DC73501 |
AZ-66
AZ-66 is a highly potent S1R/S2R antagonist with Ki of 0.31/1.76 nM, respectively. |
1259949-59-1 |
DC73502 |
CM-304
CM-304 is a potent, selective sigma-1 receptor (S1R) antagonist with Ki of 3.41 nM, 100-fold selective over S2R. |
1350296-21-7 |
DC73503 |
GM310
GM310 is a small molecule inhibitor of glycolysis, proteotoxicity, inflammation, and impairments in animal models of Alzheime's, Huntington's, and stroke by activation of the Sigma-1 receptor. |
2770374-87-1 |
DC73504 |
JR1-157
Featured
JR1-157 is a potent selective sigma 2 receptor (σ2R) ligand with Ki value of 47 nM, >10-fold selectivity over σ1R. |
2446964-31-2 |
DC73505 |
MAM03055A
MAM03055A is a novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity, exhibits high affinity and strong preference for sigma-2 receptor with Ki of 55.9 nM. |
|
DC73506 |
RC-752
RC-752 is a potent, seletive sigma-1 receptor (S1R) antagonist with Ki of 6.2 nM, 50-fold selective over S2R, shows antinociceptive activity. |
1808994-61-7 |
DC73507 |
WLB-89462
Featured
WLB-89462 (WLB89462) is a potent, highly selective sigma-2 receptor (σ2R) ligand with Ki of 13 nM, >100-fold selective over σ1R (Ki=1777 nM). |
2849471-75-4 |
DC73508 |
CRN02481
CRN02481 is a potent and selective SST5 receptor agonist with EC50 of 0.37 nM (human SST5), with excellent selectivity against SST1, SST2, SST3 and SST4 receptors. |
2374259-11-5 |
DC73509 |
S6821
Featured
S6821 (S 6821) is a potent and selective bitter taste receptor TAS2R8 with IC50 of 21 nM. |
1119831-25-2 |
DC73510 |
Org 274179-0
Featured
Org 274179-0 is a highly potent, allosteric antagonist of the thyroid-stimulating hormone receptor (TSH receptor), inhibits bTSH-, hTSH- and M22-mediated CRE-luciferase transactivation in the CHO cell line. |
1421683-12-6 |
DC73511 |
SYD5115
(SYD-5115, SYD 5115)
SYD5115 (SYD-5115) is a potent, selective and orally bioavailable thyrotropin receptor (TSH-R) antagonist with IC50 of 48 and 62 nM for rTSHR and hTSHR, respectively. |
|
DC73512 |
OPC-61815
OPC-61815 is a water-soluble phosphate ester pro-drug of Tolvaptan (Cat# PC-45125), which is an orally active vasopressin V2 receptor antagonist. |
942619-79-6 |
DC73513 |
RGH-122
RGH-122 is a potent, selective, and orally bioavailable V1a receptor antagonist with Ki/IC50 of 0.3/0.9 nM (hV1a) respectively, >100-fold selectiive over V2 receptor. |
2355304-05-9 |
DC73514 |
CMP-1611
CMP-1611 is a small molecule inhibitor of protease of the complement classical pathway, C1r, directly inhibits classical pathway-specific complement activation in a dose-dependent manner. |
1340929-37-4 |
DC73515 |
DF3016A
DF3016A (DF 3016A) is a potent and selective C5aR inhibitor with IC50 of 50 nM (C5a-induced human PMN migration and IC50 of 45 and 37 nM against rat and mouse C5aR, respectively. |
2351103-44-9 |
DC73516 |
T-ALZ01
T-ALZ01 (CMP-1696) is a small molecule inhibitor of complement component C1r. |
1623080-45-4 |
DC73517 |
WWGKKYRASKLGLAR
Peptide WWGKKYRASKLGLAR is a super agonist of complement factor C3aR, 12-15 times more active than natural C3a. |
130154-64-2 |
DC73518 |
MK-886
MK-886 (L-663,536) is a potent, selective and orally active inhibitor of 5-lipoxygenase-activating protein (FLAP) with IC50 of 30 nM. |
118414-82-7 |
DC73519 |
Rytvela
Rytvela (Peptide 101.10) is a potent, selective, allosteric negative modulator (antagonist) of IL-1 receptor I (IL-1RI), inhibits dose-dependently IL-1-induced PGE2 formation (IC50= 0.5 nM) and IL-1-induced human thymocyte (TF-1 cell) proliferation (IC50= |
868844-53-5 |
DC73520 |
KME-2780
KME-2780 (KME2780) is a potent and selective dual IRAK1 and IRAK4 (IRAK1/4) inhibitor with IC50 of 19 and 0.5 nM, respectively. |
2968466-26-2 |